Results 141 to 150 of about 4,473,643 (292)

Cellular Toxicity of Short‐ and Long‐Term Exposures to Polystyrene Nanoplastics and Microplastics in Fish Skin Cell Derived From Fathead Minnow (Pimephales promelas)

Journal of Applied Toxicology, EarlyView.
ABSTRACT The ubiquitous presence of microplastics and nanoplastics (MNPs) is raising concerns about their impact on the health of humans and other living organisms. Due to its tiny size, this particle can accumulate and circulate in the body after uptake, resulting in a variety of harmful outcomes on the organism, such as increased oxidative stress and
Trang Thi Nguyen, Kiyun Park, Ihn‐Sil Kwak   +2 more
wiley   +1 more source

Exclusive enteral nutrition containing transforming growth factor‐β improves intestinal barrier function in a colitis mouse model

Journal of Pediatric Gastroenterology and Nutrition, EarlyView.
Abstract Objectives Exclusive enteral nutrition (EEN) is the first‐line treatment for pediatric Crohn's disease, but its mechanisms of action remain poorly understood. Our aim was to identify the mechanisms that could explain the anti‐inflammatory effects of EEN, studying the nutritional composition and transforming growth factor‐β (TGF‐β) effects, in ...
Kawthar Boumessid, Vickie Lacroix, Ekaterina Ovtchinnikova, Sophie Thenet, Marie Carriere, Frédérick Barreau, Emmanuel Mas   +6 more
wiley   +1 more source

Table_1_Mucosal affairs: glycosylation and expression changes of gill goblet cells and mucins in a fish–polyopisthocotylidan interaction.XLSX [Dataset]

[Introduction]: Secreted mucins are highly O-glycosylated glycoproteins produced by goblet cells in mucosal epithelia. They constitute the protective viscous gel layer overlying the epithelia and are involved in pathogen recognition, adhesion and ...
Oswaldo Palenzuela (4721736), Enrique Riera-Ferrer (13449708), Muñoz-Berruezo, Uxue, Raquel Del Pozo (13770765), Estensoro, Itziar, M. Carla Piazzon (5576864), Riera-Ferrer, E., Palenzuela, Oswaldo, Sitjà-Bobadilla, Ariadna, Piazzon de Haro, María Carla, Ariadna Sitjà-Bobadilla (421074), Pozo, R. del, Itziar Estensoro (421070), Uxue Muñoz-Berruezo (18330699)   +13 more
core   +1 more source

Congenital short bowel syndrome: Clinical aspects by systematic review

JPGN Reports, EarlyView.
Abstract Objectives Congenital short bowel syndrome (CSBS) is a rare intestinal disorder characterized by inborn shortening of the bowel with mainly mutations in Coxsackie and Adenovirus receptor‐like membrane protein (CLMP) and Filamin A (FLNA) genes.
Barblin Remund, Susanne Schibli, Christiane Sokollik   +2 more
wiley   +1 more source

Table_2_Mucosal affairs: glycosylation and expression changes of gill goblet cells and mucins in a fish–polyopisthocotylidan interaction.XLSX [Dataset]

[Introduction]: Secreted mucins are highly O-glycosylated glycoproteins produced by goblet cells in mucosal epithelia. They constitute the protective viscous gel layer overlying the epithelia and are involved in pathogen recognition, adhesion and ...
Oswaldo Palenzuela (4721736), Enrique Riera-Ferrer (13449708), Muñoz-Berruezo, Uxue, Raquel Del Pozo (13770765), Estensoro, Itziar, M. Carla Piazzon (5576864), Riera-Ferrer, E., Palenzuela, Oswaldo, Sitjà-Bobadilla, Ariadna, Piazzon de Haro, María Carla, Ariadna Sitjà-Bobadilla (421074), Pozo, R. del, Itziar Estensoro (421070), Uxue Muñoz-Berruezo (18330699)   +13 more
core   +1 more source

Effect of Notch1 on Vocal Fold Re‐Epithelization After Acute Injury

The Laryngoscope, EarlyView.
Conditional deletion of Notch1 in Lrig1‐expressing vocal fold epithelial cells impaired re‐epithelialization following naphthalene injury, resulting in sustained basal cell proliferation, abnormal epithelial differentiation, and prolonged inflammatory cell infiltration.
Jie Cai, Susan L Thibeault, Vlasta Lungova   +2 more
wiley   +1 more source

Toxicity Differences Between Microplastics and Nanoplastics in Organs: From Molecular Mechanisms to Potential Therapeutic Strategies

Med Research, EarlyView.
This review systematically compares the size‐dependent toxicity of microplastics and nanoplastics in the intestine, liver, kidney, lung, and brain. Particle size determines bioavailability, barrier penetration, and injury mechanisms. Because of their small size and high surface reactivity, NPs readily cross the intestinal epithelium and blood–brain ...
Yixian Cheng, Junjie Chen, Rui Fu, Jiawei Zhang, Jianguang Jia, Wei Wang, Zheng Zhang, Peng Zhang, Haosong Chen, Huake Cao, Gang Li, Weiwei Sheng, Ting Li, Bo Chen, Guodong Cao   +14 more
wiley   +1 more source

Regulation of goblet cells by diet and microbiota derived metabolites [PDF]

Trillions of commensal microbes, collectively called microbiota, reside in the mammalian intestine. Microbiota break down dietary components to produce metabolites that regulate the symbiotic relationship between the host and microbiota.
Cole, Sekani
core   +1 more source

Data_Sheet_1_Mucosal affairs: glycosylation and expression changes of gill goblet cells and mucins in a fish–polyopisthocotylidan interaction.PDF [Dataset]

[Introduction]: Secreted mucins are highly O-glycosylated glycoproteins produced by goblet cells in mucosal epithelia. They constitute the protective viscous gel layer overlying the epithelia and are involved in pathogen recognition, adhesion and ...
Oswaldo Palenzuela (4721736), Enrique Riera-Ferrer (13449708), Muñoz-Berruezo, Uxue, Raquel Del Pozo (13770765), Estensoro, Itziar, M. Carla Piazzon (5576864), Riera-Ferrer, E., Palenzuela, Oswaldo, Sitjà-Bobadilla, Ariadna, Piazzon de Haro, María Carla, Ariadna Sitjà-Bobadilla (421074), Pozo, R. del, Itziar Estensoro (421070), Uxue Muñoz-Berruezo (18330699)   +13 more
core   +1 more source

Navigating the Complexity: A Comprehensive Review of GSK‐3 Inhibition in Regenerative Medicine

Medicinal Research Reviews, EarlyView.
ABSTRACT Glycogen synthase kinase‐3 (GSK‐3) is a central regulator of numerous cellular signaling pathways, with critical roles in metabolism, proliferation, differentiation, and tissue regeneration. This review explores the multifaceted effects of pharmacological GSK‐3 inhibition across multiple body districts, focusing on its highly context‐dependent
Davide Schiroli, Alessia Merra, Chiara Marraccini, Lucia Merolle, Graziella Pellegrini, Eleonora Maurizi   +5 more
wiley   +1 more source