Results 161 to 170 of about 4,483,397 (290)

Porcine intestinal goblet cells: Guardians of mucosal immunity and barrier function. [PDF]

Anim Nutr
Cui C, Tang J, Hou J, Zhang J, Tian M, Gao K, Wang L, Jiang Z, Yang X.   +8 more
europepmc   +1 more source

Schisandrin C Targets PPARγ to Induce Ferroptosis in Colorectal Cancer Cells and Promote M1 Macrophage Polarization

Phytotherapy Research, EarlyView.
Schisandrin C: A Dual Anti‐Colorectal Cancer Strategy Targeting PPARγ. ABSTRACT Colorectal cancer (CRC) remains a leading cause of cancer mortality, necessitating novel therapeutic strategies. Schisandrin C (SinC), a bioactive lignan from Schisandra chinensis, exhibits diverse pharmacological activities, but its anti‐CRC mechanisms are poorly ...
Xiao Wei, Hong‐Ping Wen, Jian‐Bo Song, Jin‐Fang Xu, Hong‐Rui Guo   +4 more
wiley   +1 more source

Human amniotic epithelial cell-derived exosomes promote conjunctival goblet cells proliferation and mucin secretion. [PDF]

Medicine (Baltimore)
Meng T, Yang S, Wu W, Gong M, Zhang Y.
europepmc   +1 more source

Asthma: From Phenotypes to Endotypes—Beyond Type 2 Inflammation

Respirology, EarlyView.
ABSTRACT Asthma is a heterogeneous syndrome featuring variable pathophysiology, clinical presentation and treatment response. This review examines a comprehensive endotype‐phenotype framework for asthma assessment with an emphasis on characteristics beyond T2 inflammatory status alone.
Mario Fernando, Gregory G. King
wiley   +1 more source

Geometrically Constrained Growth Factor Concentration Favors Enrichment of Goblet Cells and Mucus Formation. [PDF]

ACS Biomater Sci Eng
Villegas-Novoa C, Wang Y, Wang H, Jan I, Sims CE, Allbritton NL.   +5 more
europepmc   +1 more source

Diagnostic value of plasma TFF3‐centered combined biomarker panel in early gastrointestinal cancer

VIEW, EarlyView.
In this study, a retrospective cohort was established, including gastrointestinal cancer, non‐GI cancer, and healthy controls. TFF3, CEA, and gastric function indicators were detected. TFF3 showed significantly better diagnostic performance compared with conventional gastrointestinal indicators in gastric cancer, and compared with CEA in ...
Yizhou Huang, Wenjia Guo, Xiaosi Hu, Zhangming Chen, Chen Chen, Aman Xu, Hongchen Gu, Hong Xu   +7 more
wiley   +1 more source

Spatial transcriptomics reveals compartment-specific cytotoxic T cell crosstalk with AT2 and goblet cells in advanced COPD. [PDF]

Biomark Res
Syarif AH, Reiter BFE, Avian A, Milger K, Ellmeier E, Hoefler G, Aigner C, Benazzo A, Auner S, Crnkovic S, Angiari S, Polverino F, Kwapiszewska G, Marsh LM.   +13 more
europepmc   +1 more source

Noninvasive Imaging of Conjunctival Goblet Cells as a Method for Diagnosing Dry Eye Disease in an Experimental Mouse Model. [PDF]

Transl Vis Sci Technol, 2023
Kim J, Lee J, Kim S, Yoon SH, Jo YC, Kim KH, Kim HK.   +6 more
europepmc   +1 more source

Integrative Analysis of Plasma Proteome and Genome Reveals Novel Drug Targets for Chronic Rhinosinusitis and Nasal Polyps

World Journal of Otorhinolaryngology - Head and Neck Surgery, EarlyView.
ABSTRACT Background Chronic rhinosinusitis (CRS) and nasal polyps (NP) are chronic inflammatory conditions with unsatisfactory treatment outcomes due to frequent recurrence of refractory disease. Identifying new therapeutic targets is essential. Methods We conducted a proteome‐wide Mendelian randomization (MR) analysis by integrating genome‐wide ...
En Zhou, Shi Luo, Yu Xiao, Bin Liu, Xu‐Ping Xiao   +4 more
wiley   +1 more source

Stiffness Restricts the Stemness of the Intestinal Stem Cells and Skews Their Differentiation Toward Goblet Cells. [PDF]

Gastroenterology, 2023
He S, Lei P, Kang W, Cheung P, Xu T, Mana M, Park CY, Wang H, Imada S, Russell JO, Wang J, Wang R, Zhou Z, Chetal K, Stas E, Mohad V, Bruun-Rasmussen P, Sadreyev RI, Hodin RA, Zhang Y, Breault DT, Camargo FD, Yilmaz ÖH, Fredberg JJ, Saeidi N.   +24 more
europepmc   +1 more source