Results 11 to 20 of about 50,145 (238)

Substrate for Thyroid Hormone Synthesis: Biochemistry, Evolution, and Physiology. [PDF]

FASEB J
Two proposed sequence of events for thyroxine formation in patients expressing mutant thyroglobulin. (A) (1) TSH stimulation drives expression of misfolded TG. (2) Unremitting ER stress. (3) Stress‐induced cell death. (4) Dead thyrocytes release their contents. (5) The contents become iodinated. (6) Forming thyroxine.
Young C, Arvan P.
europepmc   +2 more sources

Goiter frequency is more strongly associated with gastric adenocarcinoma than urine iodine level [PDF]

, 2013
Purpose: We designed our study to evaluate the hypothesis that gastric cancer is correlated with iodine deficiency or thyroid dysfunction. Materials and Methods: We investigated the total body iodine reserve, thyroid function status and autoimmune ...
Adabi, K., Haghpanah, V., Hatami, E., Heshmat, R., Jahangirrad, A., Keshtkar, A., Kia, A., Larijani, B., Nabizadeh, R., Rohani, D., Roshandel, G., Semnani, S., Tabaeizadeh, M.   +12 more
core   +1 more source

Total or near-total thyroidectomy versus subtotal thyroidectomy for multinodular non-toxic goitre in adults [PDF]

, 2015
Background Total thyroidectomy (TT) and subtotal thyroidectomy (ST) are worldwide treatment options for multinodular non-toxic goitre in adults.
Arezzo, Alberto, Avenia, Nicola, Barczyñski, Marcin, Cirocchi, Roberto, D'Andrea, Vito, DI ROCCO, Giorgio, Guarino, Salvatore, Randolph, Justus, Santoro, Alberto, Trastulli, Stefano   +9 more
core   +2 more sources

Iodine status in schoolchildren and pregnant women of Lazio, a central Region of Italy [PDF]

, 2019
The inhabitants of Lazio, similarly to those of other Italian regions, have been historically exposed to the detrimental effects of an inadequate intake of iodine.
Baldini, Enke, Centanni, Marco, D'Armiento, Eleonora, Ulisse, Salvatore, Virili, Camilla   +4 more
core   +1 more source

Upregulation of TSHR, TTF-1, and PAX8 in Nodular Goiter Is Associated with Iodine Deficiency in the Follicular Lumen

International Journal of Endocrinology, 2016
Objective. It has been testified that iodine regulates thyroid function by controlling thyroid-restricted genes expression and is closely related to diffuse goiter and thyroid dysfunction. However, the effects of follicular lumen iodine, the main form of
Huibin Huang, Lijun Chen, Bo Liang, Huiyao Cai, Qingyan Cai, Yaxiong Shi   +5 more
doaj   +1 more source

Substernal goiter and laryngopharyngeal reflux

Archives of Endocrinology and Metabolism, 2017
Objective This study aims to compare the prevalence of laryngopharyngeal reflux signs between two groups of patients undergoing thyroidectomy for voluminous goiter: substernal goiters and voluminous cervical goiter without thoracic extension.
Mariana Gonçalves Rodrigues, Vergilius José Furtado de Araujo Filho, Leandro Luongo de Matos, Flávio Carneiro Hojaij, Cesar Augusto Simões, Vergilius José Furtado de Araujo Neto, Daniel Marin Ramos, Renata Lorencetti Mahmoud, Letícia de Moraes Mosca, Gustavo Borges Manta, Erivelto Martinho Volpi, Lenine Garcia Brandão, Claudio Roberto Cernea   +12 more
doaj   +1 more source

Follicular nodules (Thy3) of the thyroid: is total thyroidectomy the best option? [PDF]

, 2014
BACKGROUND: Identification of the best management strategy for nodules with Thy3 cytology presents particular problems for clinicians. This study investigates the ability of clinical, cytological and sonographic data to predict malignancy in ...
CALO', PIETRO GIORGIO, ERDAS, ENRICO, Medas F, NICOLOSI, ANGELO, Pisano G, Podda F, Santa Cruz R   +6 more
core   +1 more source

Goiter Survey among School Children (6–12 Years) in Northern Himalayan Region

Archives of Medicine and Health Sciences, 2017
Background: Deficiency of iodine results in impairment of thyroid hormone synthesis and abnormalities grouped under the heading of “iodine deficiency disorders (IDDs).” Goiter surveys are conducted to estimate the region's iodine status. In view of this,
S Muhammad Salim Khan, Inaamul Haq, Sheikh Mohd Saleem, Mehak Nelofar, Rachel Bashir   +4 more
doaj   +1 more source

Goiter and Its Associated Factors among Adolescent High School Girls at Tach Armachiho District, Northwest Ethiopia: An Institution-Based Cross-Sectional Study

Journal of Nutrition and Metabolism, 2020
Introduction. In Ethiopia, iodine deficiency disorder (IDD) is a major public health problem. The most visible effect of IDD is the appearance of goiters, and 28 million people are affected by goiter.
Belaynew Mesfin, Bisrat Misganaw, Melkamu Tamir Hunegnaw, Esmael Ali Muhammad   +3 more
doaj   +1 more source

Amyloid goiter

International Journal of Surgery, 2008
Amyloidosis refers to a variety of conditions in which amyloid proteins are abnormally deposited in organs and/or tissues. Amyloidosis is a rare occurrence in thyroid gland.A systematic review of the published data on amyloid goiter was carried out by searching Medline and other online databases (such as Scopus and Endnote) for the period from 1951 to ...
VILLA F, DIONIGI, GIANLORENZO, TANDA, MARIA LAURA PIERA, ROVERA, FRANCESCA ANGELA, BONI, LUIGI   +4 more
openaire   +4 more sources