Results 31 to 40 of about 1,141,202 (266)
FEBS Letters, EarlyView.Fluorescent probes allow dynamic visualization of phosphoinositides in living cells (left), whereas mass spectrometry provides high‐sensitivity, isomer‐resolved quantitation (right). Their synergistic use captures complementary aspects of lipid signaling. This review illustrates how these approaches reveal the spatiotemporal regulation and quantitative
Hiroaki Kajiho +3 more
wiley +1 more source
Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation
FEBS Letters, EarlyView.Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe +3 more
wiley +1 more source
Ligamentous Injuries in Stable Ankle Fractures: An MRI-Based Study
Foot & Ankle OrthopaedicsBackground: Ankle fractures are common orthopaedic injuries, and their management is primarily determined by fracture stability. The Lauge-Hansen classification system categorizes fractures according to mechanism of injury and ligaments involved ...
Alex N. Karanja MBChB +3 more
doaj +1 more source
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
Altered JS‐2 expression in colorectal cancers and its clinical pathological relevance
Molecular Oncology, 2011 JS‐2 is a novel gene located at 5p15.2 and originally detected in primary oesophageal cancer. There is no study on the role of JS‐2 in colorectal cancer.
Alfred King-Yin Lam +6 more
doaj +1 more source
Excited States of Gold(I) Compounds, Luminescence and Gold‐Gold Bonding [PDF]
Metal-Based Drugs, 1994 It has long been established by Khan that the superoxide anion, , generates singlet oxygen, , during dismutation. Auranofin, gold‐phosphine thiols, β‐Carotene, and metal‐sulfur compounds can rapidly quench singlet O2. The quenching of the , which exists at 7752 cm-1 above the ground state triplet, may be due to the direct interaction of the singlet O2 ...
Fackler, John P. +3 more
openaire +2 more sources
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Geofluids, 2023 As the heat hazard problem in the deep mine becomes more prominent, it is difficult to alleviate the high-temperature problem by increasing the air supply and adjusting the ventilation mode alone.
Chunlong Wang +7 more
doaj +1 more source
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source