Results 41 to 50 of about 1,642,320 (310)

Epigenetic blind spots – the role of DNA methylation dynamics in stem cell‐based models of embryogenesis

open access: yesFEBS Letters, EarlyView.
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil   +4 more
wiley   +1 more source

HAMSTRING MORPHOLOGY AND STRENGTH REMAIN ALTERED 2 YEARS FOLLOWING A HAMSTRING GRAFT IN ACL RECONSTRUCTION

open access: yesOrthopaedic Journal of Sports Medicine, 2017
Background: The hamstring graft used in anterior cruciate ligament (ACL) reconstruction has been shown to lead to changes to the semitendinosus and gracilis musculature.
Christopher J. Vertullo   +5 more
doaj   +1 more source

An unusual case of invasive pleuritis and miliary Mycoplasma pneumonia during check‐point inhibitor therapy

open access: yesRespirology Case Reports, 2021
A growing body of evidence suggests that check‐point inhibitors not only increase the overall risk of infections, but, due to an altered immune response, may also result in atypical manifestations.
Daniel Bird, Maninder Singh
doaj   +1 more source

The Kumtor gold deposit in the Middle Tien Shan, Kyrgyzstan, and the application of 3-D modeling in Seequent’s Leapfrog Geo software for the geological exploration

open access: yesРуды и металлы, 2023
The Kumtor deposit is one of the largest gold deposits in the Tien Shan. The ore zones are localized in rocks of the black shale formation, in an amagmatic gently dipping structure.
Shevkunov A. G.   +3 more
doaj   +1 more source

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

The Mineralogy Characteristics of Overflow Product from Hydrocyclone in the Jiaojia Gold Mine

open access: yesYankuang ceshi, 2014
The capacity of ore treatment reached 12,000 t/d and gold recovery achieved 92% in the Jiaojia Gold Mine. Broken product has been washed with double spiral classifier, and the ore slime yield was 7%.
HU Hai-xiang   +5 more
doaj   +2 more sources

The impact of improved surgical safety checklist participation on OR efficiencies: A pretest-post test analysis

open access: yesJournal of Perioperative Nursing, 2019
Objective: To describe changes in day of surgery (DOS) cancellations and procedural delays following introduction of a practice improvement intervention to improve team members’ participation in the surgical safety checklist (SSC).
Brigid Gillespie   +5 more
doaj   +1 more source

Gold nanoprobes for theranostics

open access: yes, 2011
Gold nanoprobes have become attractive diagnostic and therapeutic agents in medicine and life sciences research owing to their reproducible synthesis with atomic level precision, unique physical and chemical properties, versatility of their morphologies,
Book-Newell, Brittany   +9 more
core   +1 more source

Pre‐analytical optimization of cell‐free DNA and extracellular vesicle‐derived DNA for mutation detection in liquid biopsies

open access: yesMolecular Oncology, EarlyView.
Pre‐analytical handling critically determines liquid biopsy performance. This study defines practical best‐practice conditions for cell‐free DNA (cfDNA) and extracellular vesicle–derived DNA (evDNA), showing how processing time, storage conditions, tube type, and plasma input volume affect DNA integrity and mutation detection.
Jonas Dohmen   +11 more
wiley   +1 more source

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