Results 241 to 250 of about 39,066 (297)

Synergistic HMGN1 and VP64 Fusions Potentiate High‐Precision and PAM‐Flexible Base Editing

Advanced Science, EarlyView.
A novel CDA1Δ‐SpRY architecture fused with HMGN1 and VP64 yields a nearly PAM‐less base editing platform. By focusing cytosine conversion predominantly at position −18, this synergistic complex ensures highly precise targeting. Demonstrating enhanced efficiency across diverse models, including yeast and rice, the platform offers a robust solution for ...
Xi Luo, Yuyao Qu, Zhengyan Ye, Zheng Li, Yuanyan Zhang, Longjiong Luo, Shaokang Li, Wei Zhao, Ming Wang, Ralph Bock, Jianmin Wan, Junjie Tan   +11 more
wiley   +1 more source

On the Overlooked Effect of Counter-Cations From Borohydrides for the Gold- and Metal- Mediated Catalytic Reduction of 4-Nitrophenol. [PDF]

Small Methods
Smolska A, Lock N, Quinson J.
europepmc   +1 more source

Inside‐Outside ROS Therapeutic Strategy Based on Piezoelectric Nano‐Urchin for Drug‐Resistant Bacteria Biofilm Infections

Advanced Science, EarlyView.
The contribution of this study lies not only in enabling effective treatment of drug‐resistant biofilm infections, but also in establishing a transferable therapeutic paradigm: Ultrasound‐triggered mechanical forces synergistically enhance piezoelectric polarization and nanozyme activity, driving functional ROS generation inside and outside biofilms ...
Xinjian Guo, Jin Yang, Mengjie An, Bingjie Lin, Tao Liu, Limin Zhang   +5 more
wiley   +1 more source

Polymer‐Based Multiparameter Sensing Integrated Photonic Chip for Health Monitoring

Advanced Science, EarlyView.
A monolithic integrated photonic chip simultaneously measures blood glucose, pressure, temperature, ECG, and sweat glucose. Combining multiple Bragg grating sensors, Mach–Zehnder modulators, and an on–‐chip demodulation unit, this compact chip (1 cm × 0.5 cm) offers robust multiparameter detection.
Xiaolin Li, Hongqiang Li, Ming Han, Xin Liu, Mingjun Ding, Ziying Niu, Dongyang Liu, Liyuan Yang, Lizhen Zhang, Francisco Hernández‐Ramírez, Lu Cao, Enbang Li   +11 more
wiley   +1 more source

Expedient Synthesis of <i>N</i>-Protected/<i>C</i>-Activated Unnatural Amino Acids for Direct Peptide Synthesis. [PDF]

J Am Chem Soc
Kohnke P, Zhang L.
europepmc   +1 more source

Gold-Catalyzed Cyclizations of 4-Alkyl-2-yn-1-yl (Oxy)cyclohexa-2,5-dien-1-ones (1) to Develop Two Cyclizations via π-Alkyne versus π-Allene Activations. [PDF]

Org Lett
Kshirsagar AS, Liao PQ, Yang T, Liu RS.
europepmc   +1 more source

NIR-II-triggered plasmonic catalysis with tip-localized enhancement: a strategy for hypoxic biofilm eradication on orthopedic implants. [PDF]

Light Sci Appl
Sun Y, Sheng F, Liang Y, Meng J, Huang K, Liu S, Qin Y, He M, Liu JW.   +8 more
europepmc   +1 more source

Biodegradable Aurum: Gold Nanosheets Undergo Biodegradation by Neutrophil Myeloperoxidase. [PDF]

Small Sci
Kurungottu P, Anilkumar AK, Poddar S, Swetha K, Anil P, Bonam SR, Kurapati R.   +6 more
europepmc   +1 more source

Recent Advances in Intramolecular C─N Bond Formation for Pyrrolidine Synthesis. [PDF]

ChemistryOpen
Kroņkalne R, Turks M.
europepmc   +1 more source

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Light in Gold Catalysis

Chemical Reviews, 2021
Within the wide family of gold-catalyzed reactions, gold photocatalysis intrinsically features unique elementary steps. When gold catalysis meets photocatalysis, a valence change of the gold center can easily be achieved via electron transfer and radical addition, avoiding the use of stoichiometric sacrificial external oxidants.
Sina Witzel, A Stephen K Hashmi, Jin Xie   +2 more
exaly   +3 more sources