Results 71 to 80 of about 520,334 (324)
Tau acetylation at K331 has limited impact on tau pathology in vivo
We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Open data, [open] access: linking data sharing and article sharing in the Earth Sciences
INTRODUCTION The norms of a research community influence practice, and norms of openness and sharing can be shaped to encourage researchers who share in one aspect of their research cycle to share in another.
Samantha Teplitzky
doaj +2 more sources
Gold or green: the debate on open access policies.
The movement for open access to science seeks to achieve unrestricted and free access to academic publications on the Internet. To this end, two mechanisms have been established: the gold road, in which scientific journals are openly accessible, and the green road, in which publications are self-archived in repositories.
openaire +3 more sources
Open Access and Institutional Repositories: The Turkish Landscape [PDF]
The development of the “Open Access” (OA) movement since early 1990s has been radically changing the scientific communication landscape. Within the last decade more universities and research institutions are recommending their scholars to make their ...
Tonta, Yaşar
core +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
Open Access Week 2011 in the Czech Republic (Report)
The awareness of open access is slowly rising in the Czech academic environment. Both green open access and gold open access have broken through thanks to Open Access Week, which has for the second time been organized by twelve Czech university libraries,
Pavla Rygelová
doaj +1 more source
Fast-Forward on the Green Road to Open Access: The Case Against Mixing Up Green and Gold
This article is a critique of: The "Green" and "Gold" Roads to Open Access: The Case for Mixing and Matching Jean-Claude Guédon Serials Review 30(4) 2004 http://dx.doi.org/10.1016/j.serrev.2004.09 ...
Harnad, Stevan
core +1 more source
Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai +4 more
wiley +1 more source
Is it worth to establishing institutional repositories? The strategies for Open Access to Spanish peer-reviewed articles. [PDF]
We examine open access to the Spanish scientific literature through investigation of a sample of peer reviewed articles in seven subject categories.
Rodríguez, Nerea, Amat, Carlos B.
core

