Results 181 to 190 of about 12,644 (309)

Causal Prediction of TP53 Variant Pathogenicity Using a Perturbation‐Informed Protein Language Model

Advanced Science, EarlyView.
A TP53‐specific predictor, CaVepP53, is developed by fine‐tuning ESMC on experimentally validated variants, quantifying pathogenicity via Euclidean distances. It outperforms general‐purpose models and extends to five cancer genes, enabling interpretable variant classification for precision medicine.
Huiying Chen, Yang Zhao, Boqiang Hu, Wuke Wang, Minfang Song, Annabeth Xinyu Zhao, Xiangyang Li, Gefei Wang, Yanfen Wang, Weiyan Zheng, Xinpeng Zhang, Xia Lin, Yanbin Yin, Xingxu Huang, Jinfang Zheng, Tingbo Liang   +15 more
wiley   +1 more source

Gold sorption on modified saponite

Записки Горного института
A potential method for modifying saponite (intercalation) ensuring its high sorption capacity for gold was theoretically and experimentally substantiated.
Valentin A. Chanturiya, Vladimir G. Minenko, Andrei L. Samusev   +2 more
doaj  

From Marshes to Mines: Germination and Establishment of <i>Crinum bulbispermum</i> on Gold Mine Tailings. [PDF]

Plants (Basel)
Clarke VC, Claassens S, Cilliers DP, Siebert SJ.   +3 more
europepmc   +1 more source

A Testis‐Specific Aralkylamine N‐Acetyltransferase Regulates Dimorphic Sperm Function and Male Fertility in Moths

Advanced Science, EarlyView.
We identify a Lepidoptera‐conserved testis‐specific arylalkylamine N‐acetyltransferase (LTNAT) that governs male moth fertility via a novel mechanism. LTNAT loss disrupts eupyrene sperm mitochondrial derivatives and impairs apyrene sperm motility, offering a safe molecular target for innovative pesticides and genetic pest control.
Hao Sun, Peng‐Yi Huang, Zhi‐Ruo Zhang, Cong‐Fen Gao, Subba Reddy Palli, Shun‐Fan Wu   +5 more
wiley   +1 more source

Mine Tailings as a Sustainable Filler for Asphalt Binder-Mastics: A Review. [PDF]

Materials (Basel)
Oguntayo DO, Mashaan NS, Shukla SK.
europepmc   +1 more source

Sphingomonas paucimobilis‐Driven Epithelial–Endothelial Transition in Adenomyosis Pathogenesis

Advanced Science, EarlyView.
This study identifies epithelial–endothelial transition (EET) as a novel adenomyosis pathogenic mechanism driven by Sphingomonas paucimobilis colonization. Systematic inhibitor experiments validate a TNFα→NF‐κB→MMP signaling cascade essential for EET. Critically, bacterial culture supernatant fails to induce pathological changes, demonstrating viable ...
Peigen Chen, Hao Shi, Junxian He, Ziyu Liu, Yuanyuan Zhu, Xiaoyan Liang, Guihua Liu, Xing Yang   +7 more
wiley   +1 more source

Phosphorus and potentially toxic elements in stream waters, sediments, mine tailings, and pines across Lake Anna watershed, VA, USA, and biochar-lime remediation. [PDF]

Environ Sci Pollut Res Int
Kohlhaas RT, Schroeder SE, Richardson JB.   +2 more
europepmc   +1 more source

PET Imaging of Cardiac Inflammation in Viral Myocarditis Using a DPP4‐Targeted Probe

Advanced Science, EarlyView.
This study describes a DPP4‐targeted PET probe for imaging myocardial inflammation by selectively targeting activated immune cells. Derived from the clinically approved small‐molecule inhibitor linagliptin, the probe demonstrates favorable biodistribution with specific cardiac uptake in myocarditis.
Wanhao Gao, Wenzhu Hu, Du Tang, Xinxin Liu, Kun Yu, Lixia Feng, Minyu Liao, Wang Lin, Wenqiang Zhu, Sanjay Rajagopalan, Xiaoli Lan, Jixin Zhong, Dao Wen Wang, Dawei Jiang, Xiaoquan Rao   +14 more
wiley   +1 more source

Study on the Mechanism of Iron Removal by Magnetic Separation from Carbide Slag Based on Isa Mill Pretreatment. [PDF]

ACS Omega
Huang J, Long F, Liu H, Liu J, Wang S, Liu J.   +5 more
europepmc   +1 more source

Pebble Mine: Fish, Minerals, and Testing the Limits of Alaska’s “Large Mine Permitting Process” [PDF]

, 2008
Parker, Geoffrey Y., Raskin, Frances M., Trasky, Lance, Woody, Carol Ann   +3 more
core   +1 more source