Results 201 to 210 of about 1,090 (261)

pH/ROS‐Responsive Injectable Hydrogel Co‐Loaded with B7‐H3 Blocker and NETs Suppressor Boosts OSCC Synergistic Immunotherapy

Advanced Science, EarlyView.
A pH/ROS‐dual‐responsive injectable hydrogel, formed by dynamic boronic ester and Schiff base crosslinking, co‐delivers enoblituzumab (B7‐H3 blocker) and Cl‐amidine (NETs suppressor). Via localized intratumoral delivery, it synergistically reprograms the immunosuppressive tumor microenvironment, overcomes T cell infiltration barriers, restores ...
Huan Li, Yun Li, Yating Hu, Yanbing Yao, Yaodong He, Jing Li, Jiaqi Tang, Zhenyan Zhao, Yan Wang, Yulun He, Xiaolong Zhang, Xinjie Yang, Jianhua Wei   +12 more
wiley   +1 more source

Optimization of the Froth Flotation Process for the Enrichment of Cu and Co Concentrate from Low-Grade Copper Sulfide Ore. [PDF]

Materials (Basel)
Marcin M, Sisol M, Laubertová M, Kurty J, Gánovská E.   +4 more
europepmc   +1 more source

De Novo Multi‐Mechanism Antimicrobial Peptide Design via Multimodal Deep Learning

Advanced Science, EarlyView.
Current AI‐driven peptide discovery often overlooks complex structural data. This study presents M3‐CAD, a generative pipeline that leverages 3D voxel coloring and a massive database of over 12 000 peptides to capture nuanced physicochemical contexts.
Xiaojuan Li, Haifan Gong, Yue Wang, Yinuo Zhao, Lixiang Li, Peijing Bao, Qingzhou Kong, Jialu Fu, Boyao Wan, Yumeng Zhang, Jinghui Zhang, Jiekun Ni, Zhongxue Han, Xueping Nan, Kunping Ju, Longfei Sun, Yuerui Ma, Huijun Chang, Mengqi Zheng, Yanbo Yu, Xiaoyun Yang, Xiuli Zuo, Haina Wang, Yanqing Li   +23 more
wiley   +1 more source

Heavy metal pollution simplifies microbial networks and enhances modularity during tailings primary succession: divergent assembly dynamics for bacterial and fungal communities. [PDF]

Front Microbiol
Li M, Liu J, Cao D, Chen X, Shi J, Hu W, Xiao C, Fang Y.   +7 more
europepmc   +1 more source

Natural Negative Feedback Loops Confer Indica‐Japonica Differentiation for Grain Size Homeostasis in Rice

Advanced Science, EarlyView.
This study reveals the genetic and molecular mechanisms controlling grain size homeostasis through fine‐tuning OsGRX8 self‐expression by two natural negative feedback loops functioning in redox‐dependent or ‐independent manners and identifies two self‐regulatory haplotypes (SRHs) for the subspecies differentiation in rice.
Xingxing Li, Meng‐en Wu, Ziqi Qiao, Junkui Huang, Juncheng Zhang, Yang Ding, Junqing Zhu, Jingyue Xu, Yuxin Huang, Wei Li, Xiaomin Su, Yue Ding, Jianwei Zhang, Yibo Li   +13 more
wiley   +1 more source

The Legacy of Mercury Contamination from Colonial Nonferrous Mining in the Southern Hemisphere. [PDF]

Environ Sci Technol
Schneider L, Guerrero S, Mudd G, Lopez MAA, Beck KK, Sun R, Haberle SG, Fletcher MS, Zawadzki A, Hintelmann H, Griffiths A, Cooke C, de Caritat P.   +12 more
europepmc   +1 more source

Radical‐Mediated, Substrate‐Independent Fabrication of Hybrid Solid–Hydrogel Materials With Tunable Crosslinking: An Initiator‐ and Crosslinker‐Free Approach

Advanced Science, EarlyView.
This work introduces a substrate‐independent, reagent‐free plasma strategy that forms radical‐rich interlayers for covalent hydrogel attachment without initiators or crosslinkers. The long‐lived radicals drive in situ gelation, creating robust, cytocompatible hybrid solid–hydrogel constructs across diverse substrates.
Ghazal Shineh, Azin Khodaei, Pardis Keikhosravani, Masoud Zhianmanesh, Yiyun Xia, Aaron Gilmour, Sina Naficy, Andrea Guzina, Daniella Bianchi, Khoon S. Lim, Fariba Dehghani, Saber Amin Yavari, Marcela Bilek, Giselle C. Yeo, Behnam Akhavan   +14 more
wiley   +1 more source

Green Low-Temperature Activation and Curing for High-Toughness Geopolymer Binders from Diabase Tailings. [PDF]

Materials (Basel)
Hu Y, Yao Y, Zhang L, Hu X, Yang X.
europepmc   +1 more source

Effect of land use, geology, and seasonality on hydrogeochemical baseline variations in a watershed impacted by human activities in the eastern Amazon. [PDF]

Environ Monit Assess
Salomão GN, Dall'Agnol R, de Almeida GS, Amarante RT, Mello GM, da Silva Júnior RO, Guimarães JTF, da Silva MS, Ferreira DM, Pontes PRM, Sahoo PK, Marques ED, da Silva Filho EV.   +12 more
europepmc   +1 more source

Rapid Oil Sands Extraction Processing Stream Composition Determination by a ¹⁹Fluorine Nuclear Magnetic Resonance Spectrometer with Fluorinated Tracers. [PDF]

ACS Omega
Yang N, Krishnamurthy K, Shen J, Trang I, Semagina N, Tan X.   +5 more
europepmc   +1 more source