Results 51 to 60 of about 2,399,802 (303)
FEBS Letters, EarlyView.In this study, we found that human cervical‐derived adipocytes maintain intracellular iron level by regulating the expression of iron transport‐related proteins during adrenergic stimulation. Melanotransferrin is predicted to interact with transferrin receptor 1 based on in silico analysis.
Rahaf Alrifai +9 more
wiley +1 more source
PathogensThe diagnosis of canine leishmaniasis (CanL) still represents a challenge due to the variable clinical manifestations and the large number of asymptomatic dogs.
Henrique C. Teixeira +11 more
doaj +1 more source
A Private Bank as Lender of Last Resort Under the Classical Gold Standard.
Jahrbuch für Wirtschaftsgeschichte, 2022 The author argues that the idea, that the Bank of England accepted Walter Bagehot's recommendations from around the 1870s onwards and adopted the role of lender of last resort for the British financial markets, is a misconception.
Ziegler Dieter
doaj +1 more source
Tau acetylation at K331 has limited impact on tau pathology in vivo
FEBS Letters, EarlyView.We mapped tau post‐translational modifications in humanized MAPT knock‐in mice and in amyloid‐bearing double knock‐in mice. Acetylation within the repeat domain, particularly around K331, showed modest increases under amyloid pathology. To test functional relevance, we generated MAPTK331Q knock‐in mice.
Shoko Hashimoto +3 more
wiley +1 more source
Calpain small subunit homodimerization is robust and calcium‐independent
FEBS Letters, EarlyView.Calpains dimerize via penta‐EF‐hand (PEF) domains. Using single‐molecule force spectroscopy, we measured the strength and kinetics of PEF–PEF homodimer binding. The interaction is robust, shows a transient conformational step before dissociation, and remains largely insensitive to Ca2+.
Nesha May O. Andoy +4 more
wiley +1 more source
An economic evaluation by a "money doctor": what Led Edwin Walter Kemmerer to Türkiye?
Trakya Üniversitesi İktisadi ve İdari Bilimler Fakültesi E-DergiThe early 1930s saw Türkiye reaching out to numerous influential economists. Türkiye received recommendations from those economists to embrace the classical economics that was effective in the pre-1914 era. The proposed strategies urged Türkiye to uphold
Emrah Yıldız
doaj +1 more source
Should the gold standard be restored?
Vestnik MGIMO-Universiteta, 2009 Статья д.э.н., профессора Кузнецова В.С. представляет собой полемическую рецензию на статью профессора, доктора экономических наук, заведующего кафедрой «Международные валютно-кредитные отношения» МГИМО Катасонова В.Ю.
V. S. Kuznetsov
doaj +1 more source
Ultrasensitive detection of lipoarabinomannan with plasmonic grating biosensors in clinical samples of HIV negative patients with tuberculosis. [PDF]
, 2019 BACKGROUND:Timely diagnosis of tuberculosis disease is critical for positive patient outcomes, yet potentially millions go undiagnosed or unreported each year.
Andama, Alfred +14 more
core +2 more sources
FEBS Letters, EarlyView.Embryo‐like structures (stembryos) are an innovative tool, but they are hindered by experimental variability and limited developmental potential. DNA methylation is crucial for mammalian development, but its status in stembryo models is poorly characterized.
Sara Canil +4 more
wiley +1 more source
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source