Results 61 to 70 of about 866,447 (264)
Potential therapeutic targeting of BKCa channels in glioblastoma treatment
Molecular Oncology, EarlyView.This review summarizes current insights into the role of BKCa and mitoBKCa channels in glioblastoma biology, their potential classification as oncochannels, and the emerging pharmacological strategies targeting these channels, emphasizing the translational challenges in developing BKCa‐directed therapies for glioblastoma treatment.
Kamila Maliszewska‐Olejniczak +4 more
wiley +1 more source
Jornal de Pediatria, 2009 OBJETIVO: O monitoramento do pH esofágico é considerado o método mais confiável para diagnosticar o refluxo gastroesofágico. No entanto, a interpretação do mesmo estudo de pH pode diferir entre observadores.
E. van Os +3 more
doaj +1 more source
BiodivNERE: Gold standard corpora for named entity recognition and relation extraction in the biodiversity domain [PDF]
, 2022 Nora Abdelmageed +7 more
openalex +1 more source
Plecstatin inhibits hepatocellular carcinoma tumorigenesis and invasion through cytolinker plectin
Molecular Oncology, EarlyView.The ruthenium‐based metallodrug plecstatin exerts its anticancer effect in hepatocellular carcinoma (HCC) primarily through selective targeting of plectin. By disrupting plectin‐mediated cytoskeletal organization, plecstatin inhibits anchorage‐dependent growth, cell polarization, and tumor cell dissemination.
Zuzana Outla +10 more
wiley +1 more source
ISLAMIC GOLD DINAR: THE HISTORICAL STANDARD
International Journal of Islamic Economics and Finance, 2018 Lately, there have been questions on what the standards for gold dinar and silver dirham should be. Since the dinar and dirham indeed formed the Shari’ah monetary standards from the time of the Prophet pbuh, our work can, therefore, only involve in the ...
Ahamed Kameel Mydin Meera
doaj
Journal of Cytology, 2018 Objective: To assess the performance of fine needle aspiration cytology (FNAC) in the diagnosis of tuberculosis mastitis. Materials and Methods: Diagnostic test performance evaluation using two methods—as compared to an alloyed gold standard as well as ...
Meherbano M Kamal +3 more
doaj +1 more source
Gold Standard Versus Treatment as Usual: Assessment Practices in the Juvenile Justice System [PDF]
, 2022 Julia Kovalenko +2 more
openalex +1 more source
Peroxidasin enables melanoma immune escape by inhibiting natural killer cell cytotoxicity
Molecular Oncology, EarlyView.Peroxidasin (PXDN) is secreted by melanoma cells and binds the NK cell receptor NKG2D, thereby suppressing NK cell activation and cytotoxicity. PXDN depletion restores NKG2D signaling and enables effective NK cell–mediated melanoma killing. These findings identify PXDN as a previously unrecognized immune evasion factor and a potential target to improve
Hsu‐Min Sung +17 more
wiley +1 more source
“Gold Standards,” Plurality and Monocultures: The Need for Diversity in Psychotherapy
Frontiers in Psychiatry, 2018 For psychotherapy of mental disorders, presently several approaches are available, such as interpersonal, humanistic, systemic, psychodynamic or cognitive behavior therapy (CBT). Pointing to the available evidence, proponents of CBT claim that CBT is the
Falk Leichsenring +8 more
doaj +1 more source
Targeted modulation of IGFL2‐AS1 reveals its translational potential in cervical adenocarcinoma
Molecular Oncology, EarlyView.Cervical adenocarcinoma patients face worse outcomes than squamous cell carcinoma counterparts despite similar treatment. The identification of IGFL2‐AS1's differential expression provides a molecular basis for distinguishing these histotypes, paving the way for personalized therapies and improved survival in vulnerable populations globally.
Ricardo Cesar Cintra +6 more
wiley +1 more source