Results 1 to 10 of about 278,673 (271)

A potent SARS-CoV-2 neutralising nanobody shows therapeutic efficacy in the Syrian golden hamster model of COVID-19 [PDF]

Nat Commun, 2021
SARS-CoV-2 remains a global threat to human health particularly as escape mutants emerge. There is an unmet need for effective treatments against COVID-19 for which neutralizing single domain antibodies (nanobodies) have significant potential.
Huo J, Mikolajek H, Bas AL, Clark J, Sharma P, Kipar A, Dormon J, Norman C, Weckener M, Clare D, Harrison P, Tree J, Buttigieg K, Salguero F, Watson R, Knott D, Carnell O, Ngabo D, Elmore M, Fotheringham S, Harding A, Ward P, Moynie L, Dumoux M, Hall Y, Hiscox J, Owen A, James W, Carroll M, Stewart J, Naismith J, Owens R.   +31 more
europepmc   +3 more sources

Comparison of the pathogenesis of SARS-CoV-2 infection in K18-hACE2 mouse and Syrian golden hamster models.

Dis Model Mech, 2022
Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2), the etiological agent of COVID-19, causes life-threatening disease. This novel coronavirus enters host cells via the respiratory tract, promoting the formation of severe pulmonary lesions and ...
Jeong H, Woo Lee Y, Park IH, Noh H, Kim SH, Kim J, Jeon D, Jang HJ, Oh J, On D, Uhm C, Cho K, Oh H, Yoon S, Seo JS, Kim JJ, Seok SH, Lee YJ, Hong SM, An SH, Yeon Kim S, Kim YB, Hwang JY, Lee HJ, Kim HB, Jeong DG, Song D, Song M, Park MS, Choi KS, Park JW, Seo JY, Yun JW, Shin JS, Lee HY, Nam KT, Seong JK.   +36 more
europepmc   +2 more sources

Ultrasonographic and macroscopic study of pregnancy in golden hamster [PDF]

Laboratory Animal Research, 2022
Background Hamster is widely used as an experimental model in the study of reproductive system. However, pregnancy diagnosis and aging always have been a challenge. ultrasonography have been used in diagnosis of pregnancy in some small laboratory animals,
Mohammad Amin Keshavarz, Asghar Mogheiseh, Mohammad Saeed Ahrari-Khafi, Reza Mahboobi   +3 more
doaj   +2 more sources

Tissue Distribution of ACE2 Protein in Syrian Golden Hamster (Mesocricetus auratus) and Its Possible Implications in SARS-CoV-2 Related Studies. [PDF]

Front Pharmacol, 2020
Recently, the Syrian golden hamster (Mesocricetus auratus) has been demonstrated as a clinically relevant animal model for SARS-CoV-2 infection. However, lack of knowledge about the tissue-specific expression pattern of various proteins in these animals ...
Suresh V, Parida D, Minz AP, Sethi M, Sahoo BS, Senapati S.   +5 more
europepmc   +3 more sources

History and prospects of intracytoplasmic sperm injection (ICSI) and the development of golden hamster ICSI embryos [PDF]

Reproductive Medicine and Biology, 2021
Background Golden (Syrian) hamsters have many advantages for the study of reproductive biology and developmental biology, including a consistent estrous cycle, a stable superovulation response, and a short gestation period.
Nami Morishita, Masanori Ochi, Toshitaka Horiuchi   +2 more
doaj   +2 more sources

Morphological, histological, and histochemical study of the adult golden hamster (Mesocricetus auratus) spleen [PDF]

Open Veterinary Journal, 2023
Background: The golden hamster is a model of choice for the investigation of many visceral and splenic infections, neoplastic and retrospective lesions. Aim: To study the morphological, histological and histochemical structure of hamsters' spleen.
Ali Ahmed Hasan, Omar Younis Altaey, Ghada Abdulrahman Sultan   +2 more
doaj   +2 more sources

Anti-COVID-19 efficacy of ivermectin in the golden hamster

bioRxiv, 2020
The devastating coronavirus disease 2019 (COVID-19) pandemic, due to SARS-CoV-2, has caused more than 47 million confirmed cases and more than 1.2 million human deaths around the globe1, and most of the severe cases of COVID-19 in humans are associated ...
de Melo GD, Lazarini F, Larrous F, Feige L, Kergoat L, Marchio A, Pineau P, Lecuit M, Lledo P, Changeux J, Bourhy H.   +10 more
europepmc   +2 more sources

Development of Taenia pisiformis in golden hamster (Mesocricetus auratus)

Parasites & Vectors, 2011
The life cycle of Taenia pisiformis includes canines as definitive hosts and rabbits as intermediate hosts. Golden hamster (Mesocricetus auratus) is a rodent that has been successfully used as experimental model of Taenia solium taeniosis. In the present
Maravilla Pablo, Avila-Ramirez Guillermina, Garcia-Cortes Ramon, Jimenez-Gonzalez Diego E, Garza-Rodriguez Adriana, Toral-Bastida Elizabeth, Flisser Ana   +6 more
doaj   +2 more sources

Dietary-Induced Elevations of Triglyceride-Rich Lipoproteins Promote Atherosclerosis in the Low-Density Lipoprotein Receptor Knockout Syrian Golden Hamster [PDF]

Frontiers in Cardiovascular Medicine, 2021
Elevated triglycerides are associated with an increased risk of cardiovascular disease (CVD). Therefore, it is very important to understand the metabolism of triglyceride-rich lipoproteins (TRLs) and their atherogenic role in animal models.
Xiao Lin, Ping Ma, Chun Yang, Jinjie Wang, Kunxiang He, Gonglie Chen, Wei Huang, Jianglin Fan, Xunde Xian, Yuhui Wang, George Liu   +10 more
doaj   +2 more sources

The golden (Syrian) hamster as a model for the study of reproductive biology: Past, present, and future

Reproductive Medicine and Biology, 2019
Background The golden (Syrian) hamster (Mesocricetus auratus) is a small rodent that belongs to the Cricetidae family. It has several unique features that are advantageous for the study of reproductive and developmental biology, including a consistent ...
Michiko Hirose, Atsuo Ogura
doaj   +2 more sources