Results 21 to 30 of about 278,673 (271)
Characterizations of Hamster Retina as a Model for Studies of Retinal Cholesterol Homeostasis
Biology, 2021 Cholesterol homeostasis in the retina, a sensory organ in the back of the eye, has been studied in mice but not hamsters, despite the latter being more similar to humans than mice with respect to their whole-body cholesterol maintenance. The goal of this
Nicole El-Darzi +6 more
doaj +1 more source
Clinical Infectious Diseases, 2020 Background A physiological small animal model that resembles COVID-19 with low mortality is lacking. Methods Molecular docking on the binding between angiotensin-converting enzyme 2 (ACE2) of common laboratory mammals and the receptor-binding domain of ...
J. Chan +23 more
semanticscholar +1 more source
Cross-linking peptide and repurposed drugs inhibit both entry pathways of SARS-CoV-2
Nature Communications, 2021 Until today effective antivirals for COVID-19 treatment are not widely available. Here, Zhao et al. characterize a dual-functional cross-linking peptide, 8P9R, that can inhibit SARS-CoV-2 virus entry in vitro and suppresses viral replication in vivo in ...
Hanjun Zhao +15 more
doaj +1 more source
mBio, 2021 There is growing evidence that coronavirus disease 2019 (COVID-19) affects males more severely than females, including compelling evidence indicating that biological sex is an important clinical factor influencing disease pathology and outcomes. In their
Rafael Tomoya Michita +1 more
doaj +1 more source
Efficient gene targeting in golden Syrian hamsters by the CRISPR/Cas9 system. [PDF]
PLoS ONE, 2014 The golden Syrian hamster is the model of choice or the only rodent model for studying many human diseases. However, the lack of gene targeting tools in hamsters severely limits their use in biomedical research.
Zhiqiang Fan +8 more
doaj +1 more source
Demodicosis in the golden hamster.
The Japanese Journal of Veterinary Science, 1986 A large number of both Demodex criceti and D aurati (Acarina: Demodicidae) were isolated from scrapings of the skin lesion of an aged golden hamster (Mesocricetus auratus) sent to a pet clinic, Takikawa, Hokkaido in December, 1976.
Kazuo Sato, Takao Sarashina
openaire +4 more sources
Sequencing, annotation and analysis of the Syrian hamster (Mesocricetus auratus) transcriptome. [PDF]
PLoS ONE, 2014 BACKGROUND:The Syrian hamster (golden hamster, Mesocricetus auratus) is gaining importance as a new experimental animal model for multiple pathogens, including emerging zoonotic diseases such as Ebola.
Nicolas Tchitchek +8 more
doaj +1 more source
Nature Communications, 2022 Since the emergence of SARS-CoV-2 several variants of concerns have been identified, with altered disease progression and transmission dynamics. Here, Armando et al.
Federico Armando +14 more
doaj +1 more source
Nutrition of the Golden Hamster.
Experimental Biology and Medicine, 1943 ConclusionsA synthetic ration containing the 6 crystalline members of the B group which will support growth and reproduction in the rat was found wholly inadequate for the hamster. The addition of para-aminobenzoic acid and inositol increased the survival time of the hamster.
Jack M. Cooperman +2 more
openaire +2 more sources
Animals, 2023 Effective vaccines are needed to fight the COVID-19 pandemic. Forty golden hamsters were inoculated with two promising vaccine candidates and eighteen animals were used in pilot trials with viral challenge.
Malan Štrbenc +7 more
doaj +1 more source