Results 131 to 140 of about 45,796 (273)
Advanced Science, EarlyView.This study presents a human Bone (and Bone Marrow)‐on‐a‐Chip model based on native human bone scaffolds and autologous cells. Dynamic perfusion and sequential cell seeding replicate the physiological bone remodeling process in vitro, enabling the long‐term culture of functional, mature bone marrow immune subpopulations.
Nina Stelzer +17 more
wiley +1 more source
3D Chromatin Architecture Provides Insights Into Leaf Trait Variation Among Pear Species
Advanced Science, EarlyView.ABSTRACT Three‐dimensional (3D) chromatin architecture plays a fundamental role in eukaryotic gene regulations, its functional significance in perennial fruit trees remains poorly characterized despite extensive applications in crop genomics. Here, we developed high‐resolution (∼5 kb) Hi‐C maps of Pyrus and compared 3D genomic architecture of three ...
Yueyuan Liu +11 more
wiley +1 more source
Ветеринарная патология, 2010 It's achieved that dog conformation improvement for majority of dog breeds could be quicken over the breeding process due to application of the reduced biomechanical model of the dogs .
doaj
PSMA8‐Containing 20S Proteasome Regulates Spermiogenesis and Male Fertility
Advanced Science, EarlyView.PSMA8 assembles s20S proteasome that degrades specific substrates in elongating spermatids. Degradation of s20S‐substrates activates translation of FXR1‐target mRNAs, which are essential for mitochondrial sheath formation and sperm morphogenesis.
Huiwen Cao +7 more
wiley +1 more source
Golden Proportion in Visual Dental Smile in Pakistani Population: A Pilot Study
, 2010 Uvod: Oduvijek se raspravljalo o tome što čini dobru dentalnu estetiku, s obzirom na to da ona može varirati od osobe do osobe, ovisno o njezinu iskustvu i društvenom okružju.
Amna Khan +5 more
core +1 more source
Proportional Preferences in Mesopotamian Architecture
مجلة النهرين للعلوم الهندسية, 2016 Proportion and proportionality have been one of the active concerns in studying the aesthetics of art and architecture. Researchers have always sought for the origin of proportion into the art and Architecture of ancient Egypt and Classical Greece ...
Saba Sami Al Ali, Samar Khadim Handhal
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Enzymatic DNA Reaction Networks for Orchestrating Stimuli‐Dependent Temporal Molecular Pulse
Advanced Science, EarlyView.We present an enzymatic DNA reaction network (EDRN) that encodes nucleic‐acid targets in time, converting inputs into a universal strand and then into programmable transient fluorescence pulses. With time‐color multiplexing, EDRN enables single‐tube high‐plex nucleic acid detection and shows strong agreement with clinical sequencing across 32 specimens.
Jiayu Yang +7 more
wiley +1 more source
Advanced Science, EarlyView.A biotin‐modified artificial insertion peptide functionalized three‐dimensional high‐curvature‐TiO2 nano‐interface was engineered in a microfluidic chip to improve the isolation efficiency of small extracellular vesicles (sEVs). This chip balanced affinity, releasability, and extendibility, enabling high‐throughput recovery of sEVs for downstream ...
Le Wang +7 more
wiley +1 more source
, 2014 The legacy of woodcarving inheritance is passed through many generations until today, therefore, it is only logic to preserve and uphold such traditions.
Abdul Kadir, Sn Sharasayyidah
core
Advanced Science, EarlyView.This study identifies ARID3A as a key immunosuppressive transcription factor in TNBC. Its inhibition activates the type I IFN pathway, boosting CD8+ T cell infiltration and sensitizing tumors to anti‐PD‐1. The FDA‐approved migraine drug Rimegepant targets ARID3A, enhances immunotherapy efficacy in preclinical models, and establishes a druggable axis to
Teng Zhou +12 more
wiley +1 more source