A distrofia muscular de Duchenne (DMD) em humanos é uma alteração neuromuscular hereditária, de caráter recessivo, ligada ao cromossomo X e causada pela ausência ou disfunção da distrofina.
Arine Pellegrino +4 more
doaj +1 more source
A distrofia muscular de Duchenne (DMD) é uma doença de origem genética, cuja principal manifestação clínica é enfraquecimento e atrofia progressiva dos músculos.
Flávio R. Alves +8 more
doaj +1 more source
International Veterinary Epilepsy Task Force consensus proposal: Medical treatment of canine epilepsy in Europe [PDF]
In Europe, the number of antiepileptic drugs (AEDs) licensed for dogs has grown considerably over the last years. Nevertheless, the same questions remain, which include, 1) when to start treatment, 2) which drug is best used initially, 3) which ...
A Fischer +148 more
core +7 more sources
Hereditary Spectrin Deficiency in Golden Retriever Dogs [PDF]
Spectrin deficiency with increased erythrocyte osmotic fragility (OF) is a hallmark of hereditary spherocytosis, which is the most common congenital hemolytic anemia in humans of northern European ancestry. A radioimmunoassay revealed that erythrocyte spectrin concentration was 50-65% of normal in 5 adult Golden Retriever dogs, which had recovered from
Slappendel, R.J. +3 more
openaire +3 more sources
Sebaceous Adenoma Case in a Golden Retriever Dog
Background: Sebaceous adenoma is a benign tumour originating from the skin's sebaceous glands. These tumours can arise in older and middle-aged dogs, typically on various body parts, head, and extremities.
Palagan Senopati Sewoyo +1 more
doaj +1 more source
Differences in clinicopathologic variables between Borrelia C6 antigen seroreactive and Borrelia C6 seronegative glomerulopathy in dogs. [PDF]
BackgroundRapidly progressive glomerulonephritis has been described in dogs that seroreact to Borrelia burgdorferi, but no studies have compared clinicopathologic differences in Lyme-seroreactive dogs with protein-losing nephropathy (PLN) versus dogs ...
Goldstein RE +6 more
core +1 more source
Tadalafil Treatment Delays the Onset of Cardiomyopathy in Dystrophin‐Deficient Hearts
BackgroundCardiomyopathy is a leading cause of mortality among Duchenne muscular dystrophy patients and lacks effective therapies. Phosphodiesterase type 5 is implicated in dystrophic pathology, and the phosphodiesterase type 5 inhibitor tadalafil has ...
David W. Hammers +5 more
doaj +1 more source
LIMEtree: Interactively Customisable Explanations Based on Local Surrogate Multi-output Regression Trees [PDF]
Systems based on artificial intelligence and machine learning models should be transparent, in the sense of being capable of explaining their decisions to gain humans' approval and trust.
Flach, Peter, Sokol, Kacper
core +1 more source
Canine dystocia in 50 UK first-opinion emergency-care veterinary practices: prevalence and risk factors [PDF]
Dystocia can represent a major welfare issue for dogs of certain breeds and morphologies. First-opinion emergency-care veterinary caseloads represent a useful data resource for epidemiological research because dystocia can often result in emergency ...
Boag, A K +6 more
core +1 more source
Prevalence and risk factors for mast cell tumours in dogs in England [PDF]
BACKGROUND: Mast cell tumour (MCT) appears to be a frequent tumour type in dogs, though there is little published in relation to its frequency in dogs in the UK.
Brodbelt, D C +10 more
core +3 more sources

