Results 31 to 40 of about 242,279 (275)

Canal flare index evaluation for different dog breeds [PDF]

Ciência Rural
: This study determined the canal flare index (CFI) of four dog breeds using two distinct femoral regions as a reference. Thirty-five radiographs of the hip joints of Golden Retrievers (GRG), German Shepherds (GSG), Labrador Retrievers (LRG), and ...
Paula Regina Silva Gomide, Luís Renato Veríssimo de Souza, Caroline Ribeiro de Andrade, Rafael Manzini Dreibi, Bianca Paola Santarosa, Bruno Watanabe Minto   +5 more
doaj   +2 more sources

Translophagy—A potential link between autophagy impairment and translational errors

FEBS Letters, EarlyView.
Neurodegenerative diseases are characterised by the accumulation of abnormal proteins and protein aggregates, but their origin often remains unknown. We propose that selective autophagy removes damaged protein‐making machinery, preventing errors during protein synthesis.
Mykola V. Korolchuk, Gailing Ma, Robin Antrobus, Diego Manni, Marco Trevisan‐Herraz, Mustafa Khwaja, Max Brown, Gavin D. Richardson, Masaaki Komatsu, Daniel Erskine, Viktor I. Korolchuk, Tetsushi Kataura   +11 more
wiley   +1 more source

Utrophin, MHC and M1/M2 macrophages in GRMD dogs

Ciência Animal Brasileira, 2020
Muscular dystrophies are hereditary diseases that lead to progressive degeneration of the skeletal musculature. Golden Retriever dogs are used as animal models because they show a hereditary muscle disease similar to muscular dystrophy in humans.
Gabriela Noronha de Toledo, Julieta Rodini Engracia de Moraes   +1 more
doaj  

Pharmacological chromatin remodeling enhances response to estrogen therapy in ER+ breast cancer

Molecular Oncology, EarlyView.
Estrogen therapy elicits clinical benefit in ~ 30% of patients with endocrine‐resistant estrogen receptor (ER)‐positive breast cancer. Based on findings that ER transcriptional activation underlies response to estrogen therapy, we tested the effects of epigenetic dysregulation via pharmacological inhibition of histone deacetylases (HDACi).
Anneka L. Johnson Thomas, Barbara Karakyriakou, Patricia C. Muskus, Alyssa M. Roberts, Justin Rendleman, Alexa Warren, Hanxu Lu, Kimberly A. Birmingham, Malone K. Friedman, Abigail E. Goen, Huijuan Yang, Owen M. Wilkins, Fred W. Kolling, Eugene Demidenko, Julie M. Jorns, Brock C. Christensen, Todd W. Miller   +16 more
wiley   +1 more source

Sertolioma em cão Golden Retriever

Pubvet
O sertolioma, ou tumor de células de Sertoli, corresponde a uma neoplasia testicular funcional que pode cursar com síndrome de feminização e alopecia simétrica não pruriginosa.
Ana Paula Barbusa Hoberg, Fernanda Dickel de Andrade, Juliana Bonfim da Silveira   +2 more
doaj   +1 more source

STUDIES ON HAEMATOLOGICAL TRAITS IN DIFFERENT BREEDS OF DOG [PDF]

Exploratory Animal and Medical Research, 2011
The present study was conducted on dog during the period of June-September, 2009 at the Department of Animal Genetics and Breeding of West Bengal University of Animal and Fishery Sciences , Belgachia, Kolkata , West Bengal, India.
S. Goswami, S.Taraphder, S.Misra, A.K.Sahoo   +3 more
doaj  

495 Radon and Fracking Exposures and Lymphoma Risk in a Canine Model of non-Hodgkin Lymphoma

Journal of Clinical and Translational Science, 2023
OBJECTIVES/GOALS: The objective of this study was to determine whether residential radon and proximity to horizontal oil and drilling (fracking) are risk factors for the development of multicentric lymphoma in pet dogs, a spontaneous, immunocompetent ...
Ashleigh Tindle, Lauren Trepanier
doaj   +1 more source

Profiling neoadjuvant therapy response in rectal cancer using meta‐analysis of publicly available transcriptomic RNA‐seq datasets

Molecular Oncology, EarlyView.
This study integrates publicly available transcriptomic datasets to identify molecular signatures associated with response to neoadjuvant chemoradiotherapy in locally advanced rectal cancer. By analyzing a combination of multiple cohorts with bioinformatics approaches, we reveal biological pathways and immune‐related features that may improve ...
Aleksandra Stanojevic, Rafael Stroggilos, Mladen Marinkovic, Ana Djuric, Suzana Stojanovic‐Rundic, Radmila Jankovic, Sergi Castellvi‐Bel, Remond J.A. Fijneman, Antonia Vlahou, Jerome Zoidakis, Milena Cavic   +10 more
wiley   +1 more source

A Control of a Golden Retriever with Renal Dysplasia.

Journal of Veterinary Medical Science, 1997
A six-month-old male Golden Retriever with a three-month history of polyuria and polydipsia was examined. Hematological examinations revealed nonregenerative anemia, azotemia, high serum creatinine level, hypercalcemia, hyperphosphatemia, hypercholesterolemia, hyperamylasemia, and low level of total serum protein. Urinalysis indicated mild proteinuria,
MIYAMOTO, Tadashi, WAKIZAKA, Sonia, MATSUYAMA, Satoshi, BABA, Eiichiroh, OHASHI, Fumihito, KUWAMURA, Mitsuru, YAMATE, Jyoji, KOTANI, Takao   +7 more
openaire   +3 more sources

SPHINX31 acts as a SRPK1 inhibitor targeting the ATR/DNA‐PKcs/CHK1 replicative checkpoint to inhibit cell growth in non‐small cell lung cancer

Molecular Oncology, EarlyView.
The kinase SRPK1 directly interacts with the protein TOPBP1 and regulates the pre‐mRNA splicing of WIZ thereby contributing to the activation of the ATR/CHK1 replicative checkpoint in response to replicative stress. This allows cancer cells' genomic stability and survival.
Amani Shreim, Aurelie Genoux, Nadiia Zubchuk, Haoyang Zheng, Perla Salameh, Theo Ziegelmeyer, Fabien Dalonneau, Margot Rouchette, Christiane Oddou, Simona Miron, Helene Polveche, Adiilah Mamode Cassim, Carmen Garrido, Eleni Nikolakaki, Didier Auboeuf, Tao Jia, Sophie Zinn‐Justin, Beatrice Eymin   +17 more
wiley   +1 more source