Results 121 to 130 of about 6,758,042 (253)

Adaptive Dosing Trial Simulation Framework to Inform Dose Optimization: Case Study Using Longitudinal PKPD Models With PF‐06804103 Phase 1 Data in Participants With Human Epidermal Growth Factor Receptor 2 (HER2) Positive and Low Solid Tumors

CPT: Pharmacometrics &Systems Pharmacology, Volume 15, Issue 5, May 2026.
ABSTRACT Population models to identify optimal dosages typically include the evaluation of a drug's pharmacokinetics and the relationships with efficacy and safety. Dose modifications due to intolerable toxicities are frequently required for oncology therapeutics taken chronically and may impact antitumor activity and subsequent occurrences of adverse ...
Jerry Li, Li Zhou, Abraham C. F. Leung, Donghua Yin, Xiaoying Chen   +4 more
wiley   +1 more source

Skew-Reflected-Gompertz Information Quantifiers with Application to Sea Surface Temperature Records

Mathematics, 2019
The Skew-Reflected-Gompertz (SRG) distribution, introduced by Hosseinzadeh et al. (J. Comput. Appl. Math. (2019) 349, 132–141), produces two-piece asymmetric behavior of the Gompertz (GZ) distribution, which extends the positive to a whole dominion by an
Javier E. Contreras-Reyes, Mohsen Maleki, Daniel Devia Cortés   +2 more
doaj   +1 more source

Soil precompression stress assessed from strain‐stress data in linear scale: The need for a physically based approach

Soil Science Society of America Journal, Volume 90, Issue 3, May/June 2026.
Abstract State‐of‐the‐art models for soil compaction express soil strength by the so‐called precompression stress. The idea is to avoid stresses higher than those previously exposed to the soil. However, the quantification of soil precompression stress generally implies a problematic logarithmic transformation of the applied stress.
Per Schjønning, Michael Koppelgaard, Mathieu Lamandé   +2 more
wiley   +1 more source

Objective Posterior Analysis of kth Record Statistics in Gompertz Model

Axioms
The Gompertz distribution has proven highly valuable in modeling human mortality rates and assessing the impacts of catastrophic events, such as plagues, financial crashes, and famines.
Zoran Vidović, Liang Wang
doaj   +1 more source

On order statistics from the Gompertz–Makeham distribution and the Lambert W function

Mathematical Modelling and Analysis, 2013
The aim of this paper is twofold. First, we show that the expected value of the minimum order statistic from the Gompertz-Makeham distribution can be expressed in closed form in terms of the incomplete gamma function.
Pedro Jodra
doaj   +1 more source

Simultaneous detection of gradual and abrupt structural changes in Bayesian longitudinal modelling using entropy and model fit measures

British Journal of Mathematical and Statistical Psychology, Volume 79, Issue 2, Page 294-324, May 2026.
Abstract Although individuals may exhibit both gradual and abrupt changes in their dynamic properties as shaped by both slowly accumulating influences and acute events, existing statistical frameworks offer limited capacity for the simultaneous detection and representation of these distinct change patterns.
Yanling Li, Xiaoyue Xiong, Zita Oravecz, Sy‐Miin Chow   +3 more
wiley   +1 more source

Indirect Interactions Driven by Soil Effects Enable Coexistence Among Competing Plant Species

Ecology Letters, Volume 29, Issue 5, May 2026.
We show that soil‐mediated indirect interactions can stabilize coexistence between competing plant species. Soil conditioned by a mediating species alters the microbial communities, metabolites and nutrients, boosting the growth of the weak competitor while reducing the germination of the dominant competing species.
Ezequiel Antorán, Jaime Madrigal‐González, Rubén Bernardo‐Madrid, Miguel Á. Fernández‐Martínez, Marcelino de la Cruz, Joaquín Calatayud   +5 more
wiley   +1 more source

Endocrine‐Nutritional Synergy Between Sex Inversion and Microencapsulated Bioactives Enhances Growth, Intestinal Development, and Oxidative Stability in Nile Tilapia Larvae

Journal of Animal Physiology and Animal Nutrition, Volume 110, Issue 3, Page 339-350, May 2026.
ABSTRACT This study evaluated the combined effects of sex inversion and microencapsulated supplementation with organic acids and essential oils on growth performance, tissue morphology, gene expression, and oxidative status in Nile tilapia (Oreochromis niloticus) larvae.
Jaísa Casetta, Eliane Gasparino, Caroline Isabela da Silva, Simone Siemer, Gabriela Hernandes Cangianelli, Ricardo Souza Vasconcellos, Ricardo Pereira Ribeiro, Graciele Caroline Mari, Jaqueline Roesler, Juliana Sofientini, Diogo de Oliveira Marques, Stefania Claudino‐Silva   +11 more
wiley   +1 more source

Bayesian hierarchical modelling of bacteria growth [PDF]

Bacterial growth models are commonly used in food safety. Such models permit the prediction of microbial safety and the shelf life of perishable foods.
Ana P. Palacios, Juan Miguel Marín, Michael P. Wiper   +2 more
core  

Decomposing Shadow Prices Under Climate‐Driven Growth Scenarios: Insights From an Elk Herd Case Study

Natural Resource Modeling, Volume 39, Issue 2, May 2026.
ABSTRACT Natural capital accounting provides a framework for integrating ecological processes with economic valuation, but the mechanics of shadow price formation often remain opaque to resource managers and policymakers. Using the Clarks Fork elk herd in northwestern Wyoming as a case study, we decompose the shadow price of natural capital into its ...
Ranjit Bawa, Drew Bennett, Wai Yan Siu, Bailey Kirkland, David Finnoff, Jacob Hochard   +5 more
wiley   +1 more source