Results 201 to 210 of about 29,818 (258)

Hypogonadotropic Hypogonadism Before and After Transsphenoidal Surgery for Non‐Functioning Pituitary Adenoma

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective The effect of transsphenoidal surgery (TSS) on the hypothalamic‐pituitary‐gonadal (HPG) axis in patients with non‐functioning pituitary adenomas (NFPA) is underexplored, especially in women. Our aim was to investigate the HPG axis function before and after TSS, its association with quality of life (QoL), and to identify factors that ...
Victor Hantelius   +6 more
wiley   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu   +5 more
wiley   +1 more source

Exploring the Impact of RNU4‐2 Defects on Neurodevelopmental Disorders in a Korean Population

open access: yesClinical Genetics, EarlyView.
Among 15 450 Korean individuals, noncoding RNU4‐2 variants, primarily the recurrent de novo n.64_65insT, make up 0.72% of neurodevelopmental disorders. Modeling and RNA‐seq suggest U4/U6 disruption and abnormal 5′ splice‐site selection, supporting routine use of WGS analysis for reanalyzing unresolved cases. ABSTRACT Neurodevelopmental disorders (NDDs)
Juhyeon Hong   +20 more
wiley   +1 more source

Human IDO2 exhibits unique binding affinities distinct to those of human IDO1

open access: yesThe FEBS Journal, EarlyView.
Although indoleamine 2,3‐dioxygenase 2 (IDO2) is highly homologous to IDO1, it displays markedly lower catalytic activity. We found that IDO2 binds L‐tryptophan (L‐Trp) in a flipped orientation stabilized by the IDO2‐specific residue His143. Replacement of His143 with the IDO1‐equivalent tyrosine restored an IDO1‐like binding mode and increased ...
Shunsuke Nogi   +8 more
wiley   +1 more source

Post‐Release Survival of the Pelagic Stingray (Pteroplatytrygon violacea, Bonaparte, 1832) in French Longline Fisheries in the Northwestern Mediterranean Sea

open access: yesFisheries Management and Ecology, EarlyView.
ABSTRACT Bycatch remains a critical challenge in global fisheries, even when using selective gears such as longlines. In the French longline fishery targeting Atlantic bluefin tuna (Thunnus thynnus) in the Gulf of Lion, the common pelagic stingray (Pteroplatytrygon violacea) is the primary bycatch species.
Antoine Landreau   +5 more
wiley   +1 more source

Manual to determine gonadal maturity of Baltic herring

open access: yes, 2008
Bucholtz, Rikke Hagstrøm   +2 more
openaire   +1 more source

Vertical Habitat Use by Japanese Jack Mackerel Trachurus japonicus Inferred From a Biologging Study in Tokyo Bay

open access: yesFisheries Oceanography, EarlyView.
ABSTRACT The movement ecology of Trachurus japonicus in the adult stage remains poorly understood because observing their underwater behavior over long periods is challenging. This study aimed to examine vertical habitat use by T. japonicus using electronic tags. Ninety fish were tagged and released in November 2022 in Tokyo Bay, Japan.
Junji Kinoshita   +3 more
wiley   +1 more source

The Staircase Chart: Visualising Vertical and Cross‐Shelf Movements and Dispersal of Early‐Life Fish, Applied to Japanese Jack Mackerel

open access: yesFisheries Oceanography, EarlyView.
ABSTRACT Dispersal during early life stages is a critical process shaping marine fish connectivity and population dynamics, yet direct field observations at the individual level remain elusive. This has limited our understanding of the factors controlling dispersal, including the impact of active swimming by larvae and juveniles. Here, we present a new
Tatsuya Sakamoto   +4 more
wiley   +1 more source

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