Results 131 to 140 of about 21,983 (289)

Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To describe the bioactivity of circulating androgens during pubertal transition as determined by an in vitro bioassay assessing androgen receptor (AR) activation, and to compare these findings with circulating concentrations of total testosterone (total T) measured by LC‐MS/MS.
Andrés Felipe Ø. Fritzbøger   +10 more
wiley   +1 more source

Steroidogenic differentiation of human amniotic membrane-derived mesenchymal stem cells into a progesterone-/androgen-producing cell lineage by SF-1 and an estrogen-producing cell lineage by WT1−KTS

open access: yesFrontiers in Endocrinology
BackgroundSex steroid hormones, primarily synthesized by gonadal somatic cells, are pivotal for sexual development and reproduction. Mice studies have shown that two transcription factors, steroidogenic factor 1 (SF-1) and Wilms’ tumor 1 (WT1), are ...
Yumiko Miyazaki   +5 more
doaj   +1 more source

Symmetric Tensor Decomposition by an Iterative Eigendecomposition Algorithm [PDF]

open access: yesarXiv, 2014
We present an iterative algorithm, called the symmetric tensor eigen-rank-one iterative decomposition (STEROID), for decomposing a symmetric tensor into a real linear combination of symmetric rank-1 unit-norm outer factors using only eigendecompositions and least-squares fitting. Originally designed for a symmetric tensor with an order being a power of
arxiv  

Salivary Testosterone, Androstenedione and 11‐Oxygenated 19‐Carbon Concentrations Differ by Age and Sex in Children

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Background The diagnosis and management of childhood adrenal disorders is challenging. Clinical markers of hormone excess or deficiency may take months to manifest, and traditional biomarkers correlate only partially with clinical outcomes.
Julie Park   +9 more
wiley   +1 more source

Sex differences in addiction: gonadal hormones and substance use effects in women

open access: yesEuropean Psychiatry
Substance use disorders (SUD) affect differentially women and men. Although the prevalence has been reported higher in men, those women with addictive disorders present a more vulnerable profile and are less likely to enter treatment than men. The aim of
F. Fonseca
doaj   +1 more source

Transgender people’s knowledge about the adverse effects of cross-hormonization: challenges for nursing [PDF]

open access: yesRevista Brasileira de Enfermagem
Objectives: to identify trans women’s and men’s knowledge about the adverse effects of cross-hormonization and understand the repercussions of hormonization practices on trans women’s and men’s health.
Andréa Felizardo Ahmad   +7 more
doaj   +1 more source

Delayed Bone Maturation and Extended Growth Phase as Distinctive Features of 17α‐Hydroxylase/17,20‐Lyase Deficiency: A Retro‐Prospective Study of a Large Patient Cohort

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction Worldwide, combined 17‐hydroxylase/17,20‐lyase deficiency (CYP17D) is a rare form of congenital adrenal hyperplasia, but it is the second most prevalent type in Brazil. An absence of sexual differentiation and hypergonadotropic hypogonadism arise from a reduction in the usual pattern of sex steroid formation in the adrenals and ...
Rafaela Fontenele   +9 more
wiley   +1 more source

Noninvasive methods for estradiol recovery from infant fecal samples

open access: yesFrontiers in Physiology, 2010
While the activation of the infant hypothalamic-pituitary-gonadal (HPG) axis and the existence of a postnatal gonadotrophin surge were first documented in the early 1970s, study of the longitudinal development of gonadal hormones in infancy, and the ...
Amanda L Thompson   +4 more
doaj   +1 more source

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