Role of Gonadal Steroid Hormones in the Eye: Therapeutic Implications [PDF]
Gonadal steroid hormones are critical regulatory substances involved in various developmental and physiological processes from fetal development through adulthood. These hormones, derived from cholesterol, are synthesized primarily by the gonads, adrenal
Javier Valero-Ochando+4 more
doaj +6 more sources
Impact of sex in the prevalence and progression of glioblastomas: the role of gonadal steroid hormones [PDF]
Background As in other types of cancers, sex is an essential factor in the origin and progression of glioblastomas. Research in the field of endocrinology and cancer suggests that gonadal steroid hormones play an important role in the progression and ...
Claudia Bello-Alvarez+1 more
doaj +5 more sources
Neurosteroid Metabolites of Gonadal Steroid Hormones in Neuroprotection: Implications for Sex Differences in Neurodegenerative Disease [PDF]
Gonadal steroid hormones are neurotrophic and neuroprotective. These effects are modulated by local metabolism of the hormones within the brain. Such control is necessary to maintain normal function, as several signaling pathways that are activated by ...
Ari Loren Mendell, Neil James MacLusky
doaj +3 more sources
Gonadal steroid hormones and the hypothalamo-pituitary-adrenal axis. [PDF]
The hypothalamo-pituitary-adrenal (HPA) axis represents a complex neuroendocrine feedback loop controlling the secretion of adrenal glucocorticoid hormones. Central to its function is the paraventricular nucleus of the hypothalamus (PVN) where neurons expressing corticotropin releasing factor reside.
Handa RJ, Weiser MJ.
europepmc +6 more sources
The organizing actions of adolescent gonadal steroid hormones on brain and behavioral development. [PDF]
Adolescence is a developmental period characterized by dramatic changes in cognition, risk-taking and social behavior. Although gonadal steroid hormones are well-known mediators of these behaviors in adulthood, the role gonadal steroid hormones play in shaping the adolescent brain and behavioral development has only come to light in recent years.
Schulz KM, Sisk CL.
europepmc +6 more sources
Mechanisms of Immune Tolerance and Inflammation via Gonadal Steroid Hormones in Preterm Birth [PDF]
. In 2019, preterm births (PTB) accounted for approximately 0.66 million deaths globally. PTB is also associated with a significantly higher risk of mortality and long-term complications for newborns.
Yang Pan+8 more
doaj +2 more sources
Modulation of appetite by gonadal steroid hormones [PDF]
Several sex differences in eating, their control by gonadal steroid hormones and their peripheral and central mediating mechanisms are reviewed. Adult female rats and mice as well as women eat less during the peri-ovulatory phase of the ovarian cycle (estrus in rats and mice) than other phases, an effect under the control of cyclic changes in estradiol
Nori Geary, Lori Asarian
openaire +4 more sources
Role of gonadally synthesized steroid hormones in the colorectal cancer microenvironment [PDF]
ObjectiveTo understand the relationship between steroid hormones synthesized by the gonads and colorectal cancer as well as its tumor microenvironment, in the expectation of providing new ideas in order to detect and treat colorectal cancer.MethodsThrough reviewing the relevant literature at home and abroad, we summarized that androgens promote the ...
Wenxuan Liu+5 more
openalex +4 more sources
Background Gonadal steroid hormones have been suggested as the underlying mechanism responsible for the sexual dimorphism observed in metabolic diseases. Animal studies have also evidenced a causal role of the gut microbiome and metabolic health. However,
Jordi Mayneris-Perxachs+8 more
doaj +2 more sources
Psychomotor reminiscence as a function of gonadal steroid hormone variation [PDF]
Psychomotor reminiscence was studied in relation to endogenous variations in estrogenic hormone levels. Forty-three young adult females monitored their menstrual cycles for two replications, then reported for testing on Day 2, 8, or 14 of their cycles.
Karen C. Wells, R. B. Payne
openalex +3 more sources