Results 61 to 70 of about 20,073 (204)

Gonadal Development–Related Genes and a Male‐Specific Genetic Marker Identified in the Endangered Sichuan Taimen (Hucho bleekeri)

Integrative Zoology, EarlyView.
Integrated transcriptomic and proteomic analyses were used to validate gonadal development–related genes and to identify a sex‐specific molecular marker in Hucho bleekeri. ABSTRACT Sex determination and differentiation represent fundamental topics in reproductive biology. Sichuan taimen (Hucho bleekeri), a first‐class national protected fish species in
Qinyao Wei, Hua Li, Yeyu Chen, Huanchao Yang, Jun Du, Zhaobin Song   +5 more
wiley   +1 more source

Unveiling FOXO3's metabolic contribution to menopause and Alzheimer's disease

Experimental Gerontology
The increasing prevalence of Alzheimer's disease (AD) calls for a comprehensive exploration of its complex etiology, with a focus on sex-specific vulnerability, particularly the heightened susceptibility observed in postmenopausal women.
Christopher O'Mahony, Oscar Hidalgo-Lanussa, George E. Barreto   +2 more
doaj   +1 more source

Identification of MEF2A, MEF2C, and MEF2D interactomes in basal and Fsk‐stimulated mouse MA‐10 Leydig cells

Andrology, EarlyView.
Abstract Background Myocyte enhancer factor 2 transcription factors regulate essential transcriptional programs in various cell types. The activity of myocyte enhancer factor 2 factors is modulated through interactions with cofactors, chromatin remodelers, and other regulatory proteins, which are dependent on cell context and physiological state.
Karine de Mattos, Marie‐Pier Scott‐Boyer, Arnaud Droit, Robert S. Viger, Jacques J. Tremblay   +4 more
wiley   +1 more source

Sleep Disorders in Klinefelter Syndrome and Other Sex Chromosome Aneuploidies: A Narrative Review

Andrology, EarlyView.
ABSTRACT Background Sex chromosome aneuploidies (SCAs) are among the most frequent types of chromosomal aneuploidies and include Klinefelter syndrome (47,XXY and higher‐grade variants), 47,XYY syndrome, Turner syndrome (45,X), and trisomy X (47,XXX).
Roberto Paparella, Fabiola Panvino, Ida Pucarelli, Luigi Tarani   +3 more
wiley   +1 more source

Gold‐standard evidence and best practice guidance for menstrual cycle‐informed clinical care: An overview for clinicians

British Journal of Clinical Psychology, EarlyView.
Abstract Objectives To synthesize current evidence and provide clinically actionable recommendations for integrating menstrual cycle‐related processes—particularly hormone sensitivity, Premenstrual Dysphoric Disorder (PMDD) and Premenstrual Exacerbation (PME)—into psychological assessment, formulation and treatment.
Ellen R. Lambert, Louise N. Nolan, Katja M. Schmalenberger   +2 more
wiley   +1 more source

Physiological Basis of Sex Differences in Human Performance and Exercise‐Associated Pathology

Clinical Endocrinology, EarlyView.
ABSTRACT The presence of sex differences in human physical performance is well‐established and shaped by distinct endocrine, anatomical and physiological mechanisms. Despite sustained advances, our understanding of how inherent biological factors drive variations in exercise capacity and related pathologies is still developing.
David A. Holdsworth, Thomas J. O'Leary, Craig L. Doig, Natalie Taylor, Jasminder Dosanjh, David R. Woods, Michael J. Stacey, Robert M. Gifford   +7 more
wiley   +1 more source

Noninvasive methods for estradiol recovery from infant fecal samples

Frontiers in Physiology, 2010
While the activation of the infant hypothalamic-pituitary-gonadal (HPG) axis and the existence of a postnatal gonadotrophin surge were first documented in the early 1970s, study of the longitudinal development of gonadal hormones in infancy, and the ...
Amanda L Thompson, Amanda L Thompson, Patricia L Whitten, Michael L Johnson, Michelle L Lampl   +4 more
doaj   +1 more source

Obesity in Classic Congenital Adrenal Hyperplasia: Mechanisms, Complications and Management

Clinical Endocrinology, EarlyView.
ABSTRACT Classic congenital adrenal hyperplasia (CCAH) is an autosomal recessive genetic disorder primarily caused by 21‐hydroxylase deficiency. Although the survival rate of patients has significantly improved with glucocorticoid replacement therapy, long‐term use of supraphysiological doses and multiple factors inherent to the disease itself have led
Jialin Mu, Yue Li, Meng Sun, Yulin Li, Panpan Li, Hui Zou   +5 more
wiley   +1 more source

Histological characterisation of gonadal sex differentiation in Malabar red snapper (Lutjanus malabaricus) for aquaculture advancement

Journal of Fish Biology, EarlyView.
Abstract The Malabar red snapper (Lutjanus malabaricus) is a high‐value tropical marine species receiving growing attention for aquaculture development in Singapore and Southeast Asia. At present, seed production relies primarily on uncontrolled mass spawning in sea cages, a practice that lacks consistency, biosecurity and control of genetic ...
Bing Liang, Dean R. Jerry, Joyce Koh, Purushothaman Kathiresan, Celestine Terence, Xueyan Shen, Grace Loo, Shubha Vij, Jose A. Domingos   +8 more
wiley   +1 more source

Lipid spectrum and sex hormones content in patients with chronic hepatitis С

Zaporožskij Medicinskij Žurnal, 2018
Aim. To study the lipid metabolism indexes and sex hormones level in the blood serum of patients with chronic hepatitis C. Materials and methods. The content of hormones and lipid metabolism were determined in 33 patients with chronic hepatitis C ...
V. M. Kozko, K. V. Yurko, N. Ye. Khrystenko   +2 more
doaj   +1 more source