Results 201 to 210 of about 224,439 (383)

Determination of Androgen Bioactivity by an In Vitro Assay During Pubertal Transition in Healthy Boys

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Objective To describe the bioactivity of circulating androgens during pubertal transition as determined by an in vitro bioassay assessing androgen receptor (AR) activation, and to compare these findings with circulating concentrations of total testosterone (total T) measured by LC‐MS/MS.
Andrés Felipe Ø. Fritzbøger   +10 more
wiley   +1 more source

Gonadotropin-Releasing Hormone Action in the Pituitary: A Three Step Mechanism* [PDF]

open access: bronze, 1981
P. Michael Conn   +7 more
openalex   +1 more source

Society for Endocrinology Clinical Practice Guideline for the Evaluation of Androgen Excess in Women

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Context Androgen excess is common in women and refers to clinical or biochemical evidence of elevated androgenic steroids such as testosterone. It is associated with underlying polycystic ovary syndrome in the majority of cases. However severe androgen excess is less common and may indicate the presence of underlying adrenal or ovarian ...
Yasir S. Elhassan   +14 more
wiley   +1 more source

The Molecular Basis of Gonadotropin-Releasing Hormone (GnRH) Action in the Pituitary Gonadotrope1 [PDF]

open access: bronze, 1987
P. Michael Conn   +3 more
openalex   +1 more source

Ramadan Fasting Improves Health‐Related Quality of Life in Patients With Secondary Adrenal Insufficiency: A Prospective Interventional Case‐Control Study

open access: yesClinical Endocrinology, EarlyView.
ABSTRACT Introduction Intermittent fasting (IF) exposes patients with adrenal insufficiency (AI) to complications related to undertreatment. We aimed to determine the effect of IF during Ramadan on the quality of life of patients with secondary adrenal insufficiency (SAI) compared to healthy controls.
Mariam Mabrouk   +6 more
wiley   +1 more source

Multi‐Omics Reveal the Metabolic Changes in Cumulus Cells During Aging

open access: yesCell Proliferation, EarlyView.
Fatty acid β‐oxidation was elevated in cumulus cells from older mice. Tryptophan metabolism in aged cumulus cells was active. Supplementing with 5‐HT could mitigate aging damage in oocytes. ABSTRACT Maternal age has been reported to impair oocyte quality.
Liangyue Shi   +6 more
wiley   +1 more source

Identification of the FSH-RH as the other gonadotropin-releasing hormone

open access: yesNature Communications
In vertebrates, folliculogenesis and ovulation are regulated by two distinct pituitary gonadotropins: follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Shun Kenny Uehara   +6 more
doaj   +1 more source

Decoding the Molecular Landscape of Prepubertal Oocyte Maturation: GTPBP4 as a Key Driver of In Vitro Developmental Competence

open access: yesCell Proliferation, EarlyView.
Transcriptional and translational characteristics during goat oocyte maturation and identification of key factors, including GTPBP4, for prepubertal goat oocyte maturation. ABSTRACT The intricate mechanisms driving oocyte maturation remain only partially understood, especially within the domains of domestic animal reproduction and translational ...
Jianpeng Qin   +21 more
wiley   +1 more source

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