Results 31 to 40 of about 98,362 (270)

Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene [PDF]

, 2007
G protein-coupled receptor regulation of gene transcription primarily occurs through the phosphorylation of transcription factors by MAPKs. This requires transduction of an activating signal via scaffold proteins that can ultimately determine the outcome
Naor, Zvi, Pawson, Adam J, Maudsley, Stuart, Pope, Caroline, Bonfil, David, Davidson, Lindsay, Brown, Pamela; id_orcid, Larder, Rachel, Millar, Robert P, Karali, Dimitra, Nelson, Nancy   +10 more
core   +1 more source

Effect of luteal phase support gonadotropin-releasing hormone agonist on the endometrial receptivity and outcomes of in vitro fertilization programs [PDF]

Гинекология, 2016
Patients with tubal infertility in implantation window period show impaired endometrial receptivity with low implantation potention that is characterized by decrease in mature pinopodes level on endometrium, decreased expression of leukemia inhibitory ...
E M Savelyeva, S G Perminova, T A Demura, D A Strelchenko   +3 more
doaj  

Afferent Neuronal Control of Type-I Gonadotropin Releasing Hormone Neurons in the Human.

, 2013
Understanding the regulation of the human menstrual cycle represents an important ultimate challenge of reproductive neuroendocrine research. However, direct translation of information from laboratory animal experiments to the human is often complicated ...
Zsolt Liposits, Hrabovszky, Erik, Liposits, Zsolt, Erik Hrabovszky   +3 more
core   +1 more source

Growth Hormone (GH)-Releasing Peptide Stimulation of GH Release from Human Somatotroph Adenoma Cells: Interaction with GH-Releasing Hormone, Thyrotropin- Releasing Hormone, and Octreotide. [PDF]

, 1994
The synthetic hexapeptide GH-releasing peptide (GHRP; His-D-Trp-Ala-Trp-D-Phe-Lys-NH2) specifically stimulates GH secretion in humans in vivo and in animals in vitro and in vivo via a still unknown receptor and mechanism.
Strasburger, Christian J., Renner, U., Müller, O., Stalla, G., Brockmeier, S., Schopohl, Jochen, Strasburger, C., Müller, Otto-Albrecht, Schopohl, J., Strasburger, C. J., Werder, K., Lange, M., Werder, K. von, Stalla, G. K., Müller, O. A.   +14 more
core   +1 more source

Polymorphism of the Gonadotropin-Releasing Hormone Receptor Gene and Its Association With Production Traits in Isfahani Native Hens. [PDF]

Vet Med Sci
This research was conducted to identify genetic polymorphisms of the GNRHR gene on Isfahan native hen traits and their relationship with production traits. For this purpose, blood was taken, DNA was extracted, the target fragment was amplified and directly sequenced, and finally it was blasted with the reference gene in NCBI.
Kheiri F, Faghani M, Berenjegani MM, Gouran ST, Domakani MR.   +4 more
europepmc   +2 more sources

pS6K1 as an efficacy marker of GnRH agonist with premenopausal breast cancer

Endocrine Connections, 2019
Estradiol is a key factor for tumorigenesis and prognosis of hormone receptor-positive breast cancer. Adipocytes are one source of estradiol in patients with breast cancer. Recent studies have shown that phosphorylated ribosomal protein S6 kinase-1 plays
Chan Sub Park, Jihye Choi, Min-Ki Seong, Sung-Eun Hong, Jae-Sung Kim, In-Chul Park, Hyesil Seol, Woo Chul Noh, Hyun-Ah Kim   +8 more
doaj   +1 more source

Protein and mRNA expression of gonadotropin-releasing hormone receptor in yaks during estrus

Revista Brasileira de Zootecnia, 2018
To demonstrate the role of gonadotropin-releasing hormone (GnRH) in yaks (Bos grunniens), we characterized the expression of gonadotropin-releasing hormone receptor (GnRHR) mRNA and protein.
Sheng-dong Huo, Tao-jie Zhang, Ayimuguli Abudureyimu, Jun-lin Liu, Guo-hua Zhang, Zhong-ren Ma   +5 more
doaj   +1 more source

Ghrelin Decreases Firing Activity of Gonadotropin-Releasing Hormone (GnRH) Neurons in an Estrous Cycle and Endocannabinoid Signaling Dependent Manner.

, 2013
The orexigenic peptide, ghrelin is known to influence function of GnRH neurons, however, the direct effects of the hormone upon these neurons have not been explored, yet.
Farkas, Imre, Zsolt Liposits, Liposits, Zsolt, Vastagh, Csaba, Sárvári, Miklós, Imre Farkas, Miklós Sárvári, Csaba Vastagh   +7 more
core   +1 more source

Shape Memory Microneedle to Prevent Risks of Reproductive Hormone Therapy by Switching Sustained to Burst Release Under a Single Transdermal Insertion

Advanced Functional Materials, EarlyView.
A shape‐memory microneedle system enables reproductive hormone therapy through a single transdermal insertion. The X‐shaped device sustains follicle‐stimulating hormone release for three days, and mild heating restores the O shape to trigger burst human chorionic gonadotropin release.
Sungwoo Cho, Hyunjae Kim, Seung Eun Yu, Sangmin Lee, Ji Youn Lee, Mi‐Lan Kang, Kang Suk Lee, Young Sik Choi, Hak‐Joon Sung   +8 more
wiley   +1 more source

Profile of Relugolix in the Management of Advanced Hormone-Sensitive Prostate Cancer: Design, Development, and Place in Therapy

Drug Design, Development and Therapy, 2023
Tomoyuki Tatenuma,1,2 Hiroshi Miyamoto1,3 1Department of Pathology & Laboratory Medicine, University of Rochester Medical Center, Rochester, NY, USA; 2Department of Urology, Yokohama City University Graduate School of Medicine, Yokohama, Japan ...
Tatenuma T, Miyamoto H
doaj