Results 81 to 90 of about 224,439 (383)

Gonadotropin-releasing hormone agonist contributes to the successful implementation of in vitro fertilization in a patient with cervical endometriosis: a case report

AJOG Global Reports, 2023
This is a case report of a nulliparous young woman who suffered from prolonged menstruation and infertility for 1 year. Magnetic resonance imaging and a transvaginal ultrasound examination revealed cervical endometriosis.
Turui Yang, MD, Jieling Feng, MD, Lu Luo, PhD, Dan Zhang, PhD, Minghui Chen, PhD   +4 more
doaj  

Modeling of mouse experiments suggests that optimal anti-hormonal treatment for breast cancer is diet-dependent [PDF]

arXiv, 2023
Estrogen receptor positive breast cancer is frequently treated with anti-hormonal treatment such as aromatase inhibitors (AI). Interestingly, a high body mass index has been shown to have a negative impact on AI efficacy, most likely due to disturbances in steroid metabolism and adipokine production.
arxiv  

Gonadotropin-releasing hormone analogs: Understanding advantages and limitations

Journal of Human Reproductive Sciences, 2014
Pituitary stimulation with pulsatile gonadotropin-releasing hormone (GnRH) analogs induces both follicle-stimulating hormone (FSH) and luteinizing hormone (LH).
Pratap Kumar, A. Sharma
semanticscholar   +1 more source

Deciphering the skeletal interoceptive circuitry to control bone homeostasis

BMEMat, EarlyView.
This review introduces the skeletal interoceptive circuitry, covering the ascending signals from bone tissues to the brain (sensors), the central neural circuits that integrate this information and dispatch commands (CPU), and the descending pathways that regulate bone homeostasis (effectors).
Yefeng Wu, Jiusi Guo, Zhen Chen, Fengwei Zhang, Billy Kwok Chong Chow, Zhuofan Chen, Kelvin Wai‐Kwok Yeung, Wei Qiao   +7 more
wiley   +1 more source

Annual Banned‐Substance Review 17th Edition—Analytical Approaches in Human Sports Drug Testing 2023/2024

Drug Testing and Analysis, EarlyView.
Scenarios of drug exposure and administration as well as detection assays for drugs and methods of sports doping published between 2023 and 2024 are critically reviewed and evaluated in context with the Prohibited List 2024 as established by the World Anti‐Doping Agency.
Mario  Thevis, Tiia  Kuuranne, Hans  Geyer   +2 more
wiley   +1 more source

Addition of a carboxy-terminal tail to the normally tailless gonadotropin-releasing hormone receptor impairs fertility in female mice

eLife, 2021
Gonadotropin-releasing hormone (GnRH) is the primary neuropeptide controlling reproduction in vertebrates. GnRH stimulates follicle-stimulating hormone (FSH) and luteinizing hormone (LH) synthesis via a G-protein-coupled receptor, GnRHR, in the pituitary
Chirine Toufaily, Jérôme Fortin, Carlos AI Alonso, Evelyne Lapointe, Xiang Zhou, Yorgui Santiago-Andres, Yeu-Farn Lin, Yiming Cui, Ying Wang, Dominic Devost, Ferdinand Roelfsema, Frederik Steyn, Aylin C Hanyaloglu, Terence E Hébert, Tatiana Fiordelisio, Derek Boerboom, Daniel J Bernard   +16 more
doaj   +1 more source

Long-term, low-dose lead exposure alters the gonadotropin-releasing hormone system in the male rat. [PDF]

, 2002
Lead is a male reproductive toxicant. Data suggest that rats dosed with relatively high levels of lead acetate for short periods of time induced changes in the hypothalamic gonadotropin-releasing hormone (GnRH) at the molecular level, but these changes ...
Chapin, Robert E, Gentzschein, Elisabet, Sokol, Rebecca Z, Stanczyk, Frank Z, Wan, Yu-Jui Y, Wang, Saixi   +5 more
core   +2 more sources

The Impact of Triptorelin on Hormone Levels in Human and Its Metabolite Confirmation Using Liquid Chromatography–Ion Trap/Time‐of‐Flight Mass Spectrometry (LC/MS‐IT‐TOF) and Liquid Chromatography–Orbitrap (LC‐Orbitrap) for Doping Control Analysis

Drug Testing and Analysis, EarlyView.
Triptorelin (5–10) confirmation using LC/MS‐IT‐TOF and LC‐Orbitrap can be used as evidence of triptorelin abuse in doping control. ABSTRACT Triptorelin, a synthetic gonadotrophin‐releasing hormone (GnRH), is mainly used in the clinical treatment of prostate cancer.
Navaporn Saardpun, Cholsittapan Asawesna, Seksun Kaewklam, Premsant Sangkhum, Wisoot Kongchareonsombat, Thanit Kusamran, Darawan Pinthong   +6 more
wiley   +1 more source

Regulation of Gonadotropin-Releasing Hormone-(1–5) Signaling Genes by Estradiol Is Age Dependent

Frontiers in Endocrinology, 2017
Gonadotropin-releasing hormone (GnRH) is a key regulatory molecule of the hypothalamus–pituitary (PIT)–gonadal (HPG) axis that ultimately leads to the downstream release of estradiol (E2) and progesterone (P).
Bradly M. Bauman, Weiling Yin, Andrea C. Gore, T. John Wu   +3 more
doaj   +1 more source

Successful outcome of a pregnancy derived from premature ovulation in a gonadotropin‐releasing hormone antagonist protocol: A case report

Clinical Case Reports, 2021
In the gonadotropin‐releasing hormone (GnRH) antagonist protocol, it is necessary to reinforce contraceptive guidance assuming that luteinizing hormone surge is not detected by measurement of serum level and ovulation is not suppressed by GnRH antagonist.
Daichi Inoue, Yoshimasa Asada, Tomoko Ando   +2 more
doaj   +1 more source