Results 121 to 130 of about 68,932 (288)

Gonadotropin and Gonadal Steroid Release in Response to a Gonadotropin-Releasing Hormone Agonist in G_q^ɑ and G_(11)^ɑ Knockout Mice [PDF]

, 1998
In this study, we used mice lacking the G_(11)^α[ G_(11) knockout (KO)] or G_q^α gene (G_q KO) to examine LH release in response to a metabolically stable GnRH agonist (Buserelin).
Conn, Michael P., Janovick, Jo Ann, Ji, Tae, Offermanns, Stefan, Stanislaus, Dinesh, Wilkie, Thomas M.   +5 more
core  

MicroRNAs in Methamphetamine: Addiction, Neurotoxicity, and Therapeutic Potential

MedComm – Future Medicine, Volume 5, Issue 1, March 2026.
The use of METH leads to the release of dopamine from the affected brain regions, including the nucleus accumbens (NAc), ventral tegmental area (VTA), prefrontal cortex (PFC), hippocampus (Hip), and striatum. This triggers signals that alter miRNA expression, which in turn leads to differential expression of target genes.
Yacoubou Abdoul Razak Mahaman, An‐Ping Ye, Ya‐Xian Zhang, Ming‐Yu Chen, Fang Huang, Rong Liu, Ying‐Yan Fang, Xiaochuan Wang   +7 more
wiley   +1 more source

Efficacy and safety of gonadotropin-releasing hormone agonists used in the treatment of prostate cancer

Drug, Healthcare and Patient Safety, 2011
Seungtaek Choi, Andrew K LeeDepartment of Radiation Oncology, MD Anderson Cancer Center, Houston, TX, USAAbstract: Androgen deprivation therapy (ADT) is the most effective systemic treatment for prostate cancer.
Choi S, Lee AK
doaj  

Comparison of Machine Learning Models for Long-Term Recurrence of Endometriosis Treated by Laparoscopy Combined With GnRHa

Clinical and Experimental Obstetrics & Gynecology
Background: To construct and compare the predictive efficacy of the random forest (RF) model and gradient boosting machine (GBM) model for long-term recurrence of endometriosis (EMs) treated by laparoscopy combined with gonadotropin ...
Ke Zhou, Rong Zhu, Yue Jin
doaj   +1 more source

Considerations for Menstrual Suppression in Patients With Hematologic Malignancies

Pharmacotherapy: The Journal of Human Pharmacology and Drug Therapy, Volume 46, Issue 3, March 2026.
ABSTRACT Patients who menstruate during treatment for hematologic malignancies have a higher risk of heavy vaginal bleeding due to thrombocytopenia caused by malignancy and myelosuppressive chemotherapy. Heavy menstrual bleeding is associated with significant morbidity in this patient population, and menstrual suppression is a standard of supportive ...
Sahaana Veeravalli, Allison Schepers, Lydia L. Benitez, Martina S. Fraga   +3 more
wiley   +1 more source

Live Birth Outcomes for PCOS Patients Under the Follicular-Phase Long-Acting GnRH Agonist Protocol or Antagonist Protocol – A Retrospective Chinese Cohort

Journal of Multidisciplinary Healthcare, 2023
Jiajia Zhai,1 Junyan Zhang,2,3 Jingfang He,3 Minzhi Lv,4,5 Bozheng Zhang,6 Guanqun Li,7 Yuanjie Du,1 Guimin Hao1 1Department of Reproductive Medicine, The Second Hospital of Hebei Medical University, Shijiazhuang, People’s Republic of China; 2Shanxi ...
Zhai J, Zhang J, He J, Lv M, Zhang B, Li G, Du Y, Hao G   +7 more
doaj  

Treatment options for immune‐related adverse events associated with immune checkpoint inhibitors

British Journal of Pharmacology, Volume 183, Issue 6, Page 1271-1287, March 2026.
Abstract The immunotherapy revolution with the use of immune checkpoint inhibitors (ICIs) started with the clinical use of the first ICI, ipilimumab, in 2011. Since then, the field of ICI therapy has rapidly expanded — with the FDA approval of 10 different ICI drugs so far and their incorporation into the therapeutic regimens of a range of malignancies.
Yu Hua Chen, Tamás Kovács, Péter Ferdinandy, Zoltán V. Varga   +3 more
wiley   +1 more source

The case of ineffective conservative treatment of endometriosis of anterior abdominal wall from the point of view of the possible role of stem cells [PDF]

Гинекология, 2017
The article highlights the pathogenetic mechanisms of endometriosis outside the peritoneal cavity from the point of view of the role of bone marrow stem cells, given a possible explanation for the low efficiency of drug therapy of endometriosis outside ...
S O Dubrovina, Yu D Berlim, V S Gimbut, L V Krasilnikova, K A Areshyan, A I Lukash   +5 more
doaj  

Asthma and Infertility: A Prospective Case–Control Study on Pregnancy and Live Birth Rates in Women With Asthma Undergoing Assisted Reproduction

The Clinical Respiratory Journal, Volume 20, Issue 3, March 2026.
This large prospective cohort study shows no impact of asthma on pregnancy and live birth rate among infertile women undergoing assisted reproduction. ABSTRACT Background Previous studies have suggested a negative impact of asthma on fertility, and it has been hypothesized that the underlying inflammation is playing an important role.
Frida E. Lundberg, Amalie H. Sneckenborg, Hanna Nilsson, Kenny A. Rodriguez‐Wallberg   +3 more
wiley   +1 more source

Sex Matters: Hormonal and Chromosomal Determinants of Autoimmunity and Anti‐Cancer Immunity Across the Lifespan

Immunological Reviews, Volume 338, Issue 1, March 2026.
ABSTRACT Sex plays a key role in shaping both anti‐cancer immunity and autoimmunity. Biological factors underlying sexual dimorphism have now been identified in multiple aspects of anti‐cancer immunity and autoimmunity. These factors include sex differences in hormone levels, chromosome complement, and expression of the long non‐coding RNA XIST.
Christian G. Bustillos, Esther M. Peluso, Sophia L. Cha, Melissa G. Lechner, Maureen A. Su   +4 more
wiley   +1 more source