Results 111 to 120 of about 642,036 (246)

Targeting neutrophil extracellular traps in metabolic and immune niche: Nanomaterials for diabetes tissue regeneration

BMEMat, Volume 4, Issue 3, September 2026.
The effects of NETs on regeneration of various diabetic tissues, and strategies targeting NETs for diabetes tissue regeneration. In the diabetic environment, NETs undergo complex metabolic and immune reprogramming, leading to dynamic changes in antibacterial and proinflammatory functions, and affecting regeneration of multiple systemic tissues.
Xinyi Jiang, Muxin Yue, Kai Mao, Boon Chin Heng, Noor Azlin Yahya, Yunsong Liu, Zheng Li   +6 more
wiley   +1 more source

Multi‐Mechanistic Effects of Xylopia aethiopica Fruits on Uterine Fibroids: Insights From In Vivo and In Silico Evidence

Chemistry &Biodiversity, Volume 23, Issue 9, September 2026.
Xylopia aethiopica fruit extract modulates progesterone and estradiol levels in monosodium glutamate‐induced uterine fibroid models. In silico analyses reveal strong binding of its phytochemicals to progesterone, estrogen, VEGFR2, and TGF‐β receptors, indicating multi‐target anti‐fibroid actions involving hormonal regulation, anti‐angiogenesis, and ...
Adedokun Oluwasegun, Ume Ogochukwu, Akinsola Olubiyi, Agada Emmanuel, Adebiyi Omowumi, Idogho Eseoghena, Adedokun Folake, Adekunle Temilade   +7 more
wiley   +1 more source

Fewer Injections and Lower Drug Costs With Long‐Acting GnRH Depot Formulations: A Nationwide Analysis of 2.3 Million Patient‐Years in Japan

Cancer Reports, Volume 9, Issue 9, September 2026.
ABSTRACT Background Androgen deprivation therapy (ADT) is the base of treatment for prostate cancer, and gonadotropin‐releasing hormone (GnRH) drugs are given as depot injections. Long‐acting formulations may reduce the number of injections and the drug cost, but this impact has not been quantified in real practice.
Takashi Kawahara, Akihito Hashizume, Masanobu Yamazaki, Daiji Takamoto, Teppei Takeshima, Hiroji Uemura, Kazuhide Makiyama, Jun‐ichi Teranishi   +7 more
wiley   +1 more source

The Role and Mechanism of Incretins in Gynaecologic Diseases

Endocrinology, Diabetes &Metabolism, Volume 9, Issue 5, September 2026.
This review outlines the mechanisms of incretins in polycystic ovary syndrome, endometriosis and gynaecological cancers, highlighting the translational potential of incretin‐based therapies for metabolic‐associated gynaecological disorders. ABSTRACT Background Obesity is a major global public health concern closely linked to the development and ...
Jiayu Yan, Minyue Cao, Yan Ding, Yiqin Zhang, Yihan Sun, Genyi Jiang, Yanli Zhang, Luyao Kang, Xue Zhou, Jing Luo, Bilan Li   +10 more
wiley   +1 more source

Menopausal hormone therapy and comprehensive postmenopausal care in gynecologic cancer survivors: A position paper from the FIGO Committee on Women at Menopausal Age

International Journal of Gynecology &Obstetrics, Volume 174, Issue 3, Page 1151-1171, September 2026.
Abstract Recent advances in cancer screening, diagnosis, and treatment have greatly improved survival rates among women with gynecologic cancers. More survivors now live long enough to experience treatment‐related menopause. Vasomotor symptoms, genitourinary syndrome of menopause, sexual dysfunction, sleep issues, and long‐term risks from estrogen ...
Agnaldo Lopes da Silva‐Filho, Suvarna Khadilkar, Hema Divakar, Chiara Benedetto, Andrea R. Genazzani, Diana Ramos, Elizabete Argale, Enrique Herrera, Martha Hickey   +8 more
wiley   +1 more source

Validity of the recorded codes of gonadotropin-releasing hormone agonist treatment and orchiectomies in the Danish National Patient Registry

, 2012
Christina Gade Jespersen,1,2 Michael Borre,1 Mette Nørgaard21Department of Urology, Aarhus University Hospital, Aarhus, Denmark; 2Department of Clinical Epidemiology, Institute of Clinical Medicine, Aarhus University Hospital, Aarhus ...
Jespersen CG, Borre M, Nørgaard M   +2 more
core  

Fisetin Attenuates Uterine Leiomyoma in Rats: Potential Crosstalk Between HMGB1, SphK1/S1P, and TGF‐β Signaling

Journal of Biochemical and Molecular Toxicology, Volume 40, Issue 9, September 2026.
Fisetin attenuates monosodium glutamate‐induced uterine leiomyoma by reducing sex hormones and suppressing S1P/SphK1 signaling, HMGB1‐mediated inflammation, and fibrotic markers. These coordinated effects alleviate fibrosis and restore uterine tissue architecture, highlighting fisetin as a promising natural therapeutic candidate.
Nashwa Maghraby, Esraa Khalaf, Marwa T. Hussien, Ahmed M. A. Sobh, Nagla T. Elmelegy   +4 more
wiley   +1 more source

Gonadotropin-releasing hormone agonist against severe aggression in autism

, 2016
Aggression in patients with autism spectrum disorder (ASD) presents an important therapeutic challenge. Conventional treatment appears to be inadequate in a number of cases.
Helmerhorst, Frans M., Van Der Weiden, Robin M F,, Helmerhorst, Frans M.,, Van Der Weiden, Robin M F, Eriksson, Tomas   +4 more
core   +1 more source

Prostate Cancer Development, Progression, and Therapy

MedComm – Oncology, Volume 5, Issue 3, September 2026.
This review provides an integrated overview of prostate cancer development, progression, and therapy, spanning historical milestones, molecular mechanisms, advanced research models, and emerging therapeutic strategies. It highlights recent advances in precision diagnosis, lineage plasticity, therapy resistance, and next‐generation treatments for ...
Xin Jin, Zicheng Xiao, Zexian Ding, Wei Li, Ruijiang Zeng, Yujun Shuai, Weimin Ci, Dan Xia, Xu Zhang, Haojie Huang   +9 more
wiley   +1 more source

Successful pregnancy via assisted reproductive technology following combined high-intensity focused ultrasound, ethanol injection, and GnRH agonist therapy for refractory uterine fibroids: a case report

International Journal of Hyperthermia
Background Refractory and recurrent uterine fibroids present complex therapeutic challenges, particularly in patients who desire fertility preservation.
Qi Wan, Qingling Wang, Xue Jiao Wang, Xiaoli Wang   +3 more
doaj   +1 more source