Results 31 to 40 of about 642,036 (246)

Gonadotropin-releasing hormone agonist ovulation trigger—beyond OHSS prevention

Upsala Journal of Medical Sciences, 2020
In this review the advantages of the gonadotropin-releasing hormone agonist (GnRHa) trigger are discussed beyond those immediately associated with ovarian hyperstimulation syndrome (OHSS) prevention.
Juan Carlos Castillo, Thor Haahr, María Martínez-Moya, Peter Humaidan   +3 more
doaj   +1 more source

Comparison between the modified long gonadotropin-releasing hormone agonist protocol and the non-downregulation protocol in POSEIDON groups: a propensity score matching retrospective cohort study

Frontiers in Endocrinology, 2023
BackgroundIn vitro fertilization (IVF) is the main technique to address the infertility issue in the patient-oriented strategy encompassing individualized oocyte number (POSEIDON) population.
Chunyan Chen, Xinliu Zeng, Hanke Zhang, Qiongqiong Wei, Ying Gao, Lin Liu   +5 more
doaj   +1 more source

Congenital hypogonadotropic hypogonadism due to GnRH receptor mutations in three brothers reveal sites affecting conformation and coupling [PDF]

, 2012
Congenital hypogonadotropic hypogonadism (CHH) is characterized by low gonadotropins and failure to progress normally through puberty. Mutations in the gene encoding the GnRH receptor (GNRHR1) result in CHH when present as compound heterozygous or ...
Newton, Claire, Young, Jacques, Claire L Newton, Millar, Robert, Newton, Claire L., Guiochon-Mantel Anne, Young Jacques, Guiochon-Mantel, Anne, Millar, Robert P., Bouligand, Jerome, Newton Claire L., Millar, Robert P, Tello Javier A., Tello, Javier, Anne Guiochon-Mantel, Newton, Claire L, Tello, Javier A., Millar Robert P., Robert P Millar, Jerome Bouligand, Jacques Young, Bouligand Jerome, Tello, Javier A, Javier A Tello   +23 more
core   +2 more sources

Structure and function of sea urchin neuropeptides [PDF]

, 2010
PhDThe subject of this thesis is the identification and functional characterization of sea urchin neuropeptides. Neuropeptides are important mediators of neural signalling in all known animals with a nervous system, including bilaterians, ctenophorans ...
Rowe, Matthew Lyndon
core   +4 more sources

Gonadotropin-Releasing Hormone Agonist Therapy and Obesity in Girls [PDF]

International Journal of Endocrinology and Metabolism, 2015
Depot preparations of gonadotropin-releasing hormone agonists (GnRHa) are the gold standard drugs for the treatment of central precocious puberty. A concern about these drugs is obesity.This study aimed to investigate the effect of gonadotropin-releasing hormone agonists (GnRHa) therapy on body mass index (BMI) in girls with central precocious puberty (
Shiasi Arani, Kobra, Heidari, Fatemeh
openaire   +2 more sources

2‐Deoxyglucose Dendrimer‐Enabled Niclosamide Delivery to FRβ‐Expressing Macrophages Alleviates Endometriosis Progression and Associated Hyperalgesia

Advanced Healthcare Materials, EarlyView.
A folic acid (FA)‐conjugated 2‐deoxyglucose dendrimer selectively targets FRβ+ macrophages in endometriotic lesions, enabling precise intracellular delivery of niclosamide. This nonhormonal nanomedicine enhances drug solubility, provides controlled intracellular release, suppresses lesion growth, reduces inflammation and pain, and establishes FRβ ...
Anubhav Dhull, Mingxin Shi, Madeleine E. Harvey, Taylor M. Page, Rishi Sharma, Kenneth John Goody, Aqib Iqbal Dar, Nash S. Moawad, Vijay Kumar Sirohi, Paul S. Cooke, Kanako Hayashi, Anjali Sharma   +11 more
wiley   +1 more source

Direct evidence on the efficacy of GnRH agonist in recurrent steroid cell tumor-not otherwise specified

Gynecologic Oncology Reports, 2019
Background: Steroid cell tumor (SCT) not otherwise specified (NOS) is rare and recurrence and metastasis rarely occurs; therefore, reports regarding its treatment are limited.
Tadaharu Nakasone, Tomoko Nakamoto, Akiko Matsuzaki, Hiroshige Nakagami, Yoichi Aoki   +4 more
doaj   +1 more source

Histamine and the mechanisms of nausea and vomiting: Translating the uncertain pharmacology of cyclizine

British Journal of Clinical Pharmacology, EarlyView.
Abstract Cyclizine is a long‐established, short‐acting drug, registered for preventing motion sickness, post‐operative nausea and vomiting (PONV) and ‘vomiting of known cause’. The latter is not defined but may include pregnancy and patients receiving palliative care, historically accepted without large, controlled trials.
Gareth J. Sanger, Paul L. R. Andrews
wiley   +1 more source

Effect of Endometrium Thickness on Clinical Outcomes in Luteal Phase Short-Acting GnRH-a Long Protocol and GnRH-Ant Protocol

Frontiers in Endocrinology, 2021
ObjectiveTo investigate the factors that influence luteal phase short-acting gonadotropin-releasing hormone agonist (GnRH-a) long protocol and GnRH-antagonist (GnRH-ant) protocol on pregnancy outcome and quantify the influence.
Jie Zhang, Yi-Fei Sun, Yue-Ming Xu, Bao-jun Shi, Yan Han, Zhuo-Ye Luo, Zhi-Ming Zhao, Gui-Min Hao, Bu-Lang Gao   +8 more
doaj   +1 more source

Efficacy and related factors of levonorgestrel‐releasing intrauterine system combined with metformin in fertility‐preserving treatment for atypical endometrial hyperplasia and early endometrial cancer: A retrospective cohort study

International Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective To compare the efficacy of the levonorgestrel‐releasing intrauterine system combined with metformin versus oral progestin combined with metformin in fertility‐preserving treatment for patients with atypical endometrial hyperplasia and early endometrial cancer, and to analyze related factors affecting efficacy.
Pengpeng Gu, Jialu Gao, Yuxin Li, Mei Huang, Xiaoshuang Wang, Xin Zhao   +5 more
wiley   +1 more source