Results 51 to 60 of about 642,036 (246)

Gonadotropin-releasing-hormone signalling pathway including genes that are in the Partial Correlation Information Theory (PCIT), their effects and pathways.

open access: yes, 2020
Gonadotropin-releasing-hormone signalling pathway including genes that are in the Partial Correlation Information Theory (PCIT), their effects and pathways.
Ahmed Saleh (7222196)
core   +1 more source

At the transition from invertebrates to vertebrates a novel GnRH-like peptide emerges in amphioxus [PDF]

open access: yes, 2014
This work was supported by a grant from the Canadian Natural Sciences and Engineering Council (NSERC).Gonadotropin-releasing hormone (GnRH) is a critical reproductive regulator in vertebrates.
Roch, Graeme   +2 more
core   +1 more source

Safety, Pharmacokinetic and Pharmacodynamic Evaluation of Teverelix for the Treatment of Hormone-Sensitive Advanced Prostate Cancer: Phase 2 Loading-Dose-Finding Studies

open access: yesMedicina, 2023
Background and objectives: Teverelix drug product (DP) is a gonadotropin-releasing hormone antagonist in development for the treatment of patients with prostate cancer in whom androgen deprivation therapy is indicated. The aim of this paper is to present
Carol M. MacLean   +5 more
doaj   +1 more source

Patient reported outcomes and results of endometrial balloon ablation for the treatment of heavy menstrual bleeding: A single center observational cohort study

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Abstract Objective Heavy menstrual bleeding is one of the most common gynecologic disorders among women of reproductive age and has a significant impact on their physical, psychological, and social well‐being. Although international guidelines recommend medical therapy as the first‐line treatment, it may prove ineffective, poorly tolerated, or ...
Jonas Rudaitis   +3 more
wiley   +1 more source

Anosmin-1 modulates fibroblast growth factor receptor 1 signaling in human gonadotropin-releasing hormone olfactory neuroblasts through a heparan sulfate-dependent mechanism [PDF]

open access: yes, 2004
Defects of either anosmin-1 or fibroblast growth factor receptor 1 (FGFR1) are known to underlie hereditary Kallmann's syndrome (KS), a human disorder of olfactory and gonadotropin-releasing hormone (GnRH) neuronal ontogeny.
Guimond, S   +17 more
core   +1 more source

Menopause hormone therapy in women with cardiovascular risk factors or established ischemic heart disease: A joint FIGO and WHF position paper

open access: yesInternational Journal of Gynecology &Obstetrics, EarlyView.
Integrated approach to menopausal hormone therapy in women with cardiovascular risk factors or established ischemic heart disease, from early treatment initiation and risk stratification to individualized therapy, multidisciplinary follow‐up, and health‐system recommendations.
Chiara Benedetto   +9 more
wiley   +1 more source

Proline-rich tyrosine kinase 2 mediates gonadotropin-releasing hormone signaling to a specific extracellularly regulated kinase-sensitive transcriptional locus in the luteinizing hormone beta-subunit gene [PDF]

open access: yes, 2007
G protein-coupled receptor regulation of gene transcription primarily occurs through the phosphorylation of transcription factors by MAPKs. This requires transduction of an activating signal via scaffold proteins that can ultimately determine the outcome
Naor, Zvi   +10 more
core   +1 more source

Receptor activation in GNRH receptors [PDF]

open access: yes, 2000
Includes bibliographical ...
Ott, Thomas Ruthard
core   +1 more source

Human biomarker navigator

open access: yesiMeta, EarlyView.
The Human Biomarker Navigator integrates the disease continuum, biomarker dynamics, cross‐organ biomarker networks, biomarker classification, and technology‐driven paradigms. It maps how biomarkers link multi‐system physiology and pathology across the nervous, respiratory, endocrine, circulatory, immune, digestive, urinary, reproductive, and ...
Meng‐Yao Li   +29 more
wiley   +1 more source

Effect of gonadotropin-releasing hormone agonist on ES-2 ovarian cancer cells

open access: yesTaiwanese Journal of Obstetrics & Gynecology, 2014
Objective: Gonadotropin-releasing hormone (GnRH) receptor is found in the ovarian tissue, including epithelial ovarian cancer (EOC), suggesting that GnRH agonists may have direct action on EOC.
Kuan-Hao Tsui   +9 more
doaj   +1 more source

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