Results 301 to 310 of about 155,820 (386)

Decreased PTGES2 Farnesylation in Granulosa Cells Compromises PGE2‐Dependent Cumulus Expansion and Oocyte Maturation During Ovarian Aging

Aging Cell, Volume 25, Issue 2, February 2026.
A schematic showing decreased PTGES2 farnesylation in granulosa cells compromises PGE2‐dependent cumulus expansion and oocyte maturation during ovarian aging. In young ovaries, PTGES2 farnesylation of GCs regulates the process of cumulus expansion and oocyte maturation by facilitating PGE2 production.
Sainan Zhang, Jiahui Qi, Chuanming Liu, Huidan Zhang, Bichun Guo, Die Wu, Yicen Liu, Xin Zhen, Yang Zhang, Nannan Kang, Jidong Zhou, Guijun Yan, Chaojun Li, Lijun Ding, Haixiang Sun   +14 more
wiley   +1 more source

Evaluation of the effects of the Stop GnRH agonist with the letrozole protocol in poor ovarian responders: ABOTH randomized controlled trial. [PDF]

JBRA Assist Reprod
Saharkhiz N, Hosseini S, Kazemi M, Majdi L, Esmaeili S, Nemati M, Hosseinzadeh M, Zarisfi Z.   +7 more
europepmc   +1 more source

Pharmaceutical Evaluation of Hollow-Type Suppotitories. Part XXIII. Pharmacokinetics and Pharmacodynamics of Human Chorionic Gonadotropin (hCG) after Rectal Administration of Hollow-Type Suppositories Containing hCG.

, 2002
Kouji Kowari, Iori Hirosawa, Hirono Kurai, Naoki Utoguchi, Makiko Fujii, Yoshiteru Watanabe   +5 more
openalex   +2 more sources

Puberty‐Promoting Treatment and Psychosocial Well‐Being in Boys With Constitutional Delay of Puberty: A Randomized Controlled Trial

Clinical Endocrinology, Volume 104, Issue 2, Page 139-146, February 2026.
ABSTRACT Objective In boys, constitutional delay of growth and puberty (CDGP) has been associated with diverse negative psychosocial effects. Albeit alleviating distress is one of the main reasons for inducing pubertal development, the impact of puberty‐promoting treatment on psychosocial wellbeing is under‐researched.
Laura Kariola, Tero Varimo, Mitja Lääperi, Hanna Huopio, Sirpa Tenhola, Raimo Voutilainen, Jorma Toppari, Silja Kosola, Päivi J. Miettinen, Olli Raitakari, Marko Elovainio, Taneli Raivio, Matti Hero   +12 more
wiley   +1 more source

Extended Thymectomy via Thoracoscopy and Cervical Incision in a Child with Anterior Mediastinal Mixed Germ Cell Tumor and Paraneoplastic Precocious Puberty. [PDF]

Surg Case Rep
Yamoto M, Sugai Y, Gohda Y, Miyake H, Nomura A, Fukumoto K, Sano S, Iwafuchi H, Watanabe K.   +8 more
europepmc   +1 more source

Mixed Gonadal Dysgenesis: A Comprehensive Review of Clinical Spectrum, Diagnostic Strategies, and Management Approaches

Clinical Endocrinology, Volume 104, Issue 2, Page 92-102, February 2026.
ABSTRACT Background Mixed gonadal dysgenesis (MGD) is a rare form of differences in sex development (DSD) typically associated with 45,X/46,XY mosaicism. The phenotypic presentation of MGD varies from atypical genitalia to typical male or female appearances often associated with Turner stigmata.
Dinesh Giri, Sushil Yewale, Hannah Hickingbotham, Cara Williams, Mohamed Shalaby, Julie Alderson, Julie Park   +6 more
wiley   +1 more source

Letrozole at the Crossroads of Efficacy and Fetal Safety in Ovulation Induction: A Narrative Review. [PDF]

Biomedicines
Kaltsas A, Efthimiou A, Roidos C, Tzikoulis V, Georgiou I, Sotiriadis A, Zachariou A, Chrisofos M, Sofikitis N, Dimitriadis F.   +9 more
europepmc   +1 more source

Impact of Growth Hormone Treatment in Children From an Extended Family With ACAN ‐Related Short Stature

Clinical Genetics, Volume 109, Issue 2, Page 374-379, February 2026.
This study evaluated growth hormone (GH) therapy in children from an extended family with genetically confirmed ACAN‐related short stature. While GH treatment improved growth velocity, the response varied among individuals, and its long‐term impact on final adult height remains to be determined.
Einat Shalev‐Goldman, Ayman Asaly, Hadas Ityel, Ben Pode‐Shakked, Dalit Modan‐Moses, Yael Levy‐Shraga   +5 more
wiley   +1 more source

Male Infertility: A Comprehensive Review of Urological Causes and Contemporary Management. [PDF]

J Clin Med
Barone B, Amicuzi U, Tammaro S, Olivetta M, Stizzo M, Musone M, Napolitano L, De Luca L, Reccia P, Capone F, Lecce A, Pagano G, Imperatore S, Chianese S, Papi S, Della Rosa G, Dinacci F, Coppola M, Madonna A, Grillo M, Di Domenico D, Del Giudice F, Caputo VF, Del Biondo D, Falabella R, Crocetto F.   +25 more
europepmc   +1 more source

Molecular profile of atypical Leydig cell tumours

Histopathology, Volume 88, Issue 3, Page 628-635, February 2026.
Copy number variations by themselves are not sufficient to discriminate between benign and potential malignant Leydig cell tumours (LCTs). Genomic instability was only detected in malignant and atypical cases, and not in any benign tumours. Currently, the presence of metastasis remains the only malignant criterion for LCTs.
Muhammad F.K. Choudhry, Diogo Caires, Yaser Gamallat, Asli Yilmaz, Fadi Brimo, Bob Argiropoulos, Tarek A. Bismar   +6 more
wiley   +1 more source