Results 151 to 160 of about 8,572,674 (314)

Microbiome‐blood–brain barrier interactions in aging — mechanisms and therapeutic potential

FEBS Letters, EarlyView.
Aging reshapes the gut microbiome (↓SCFA‐producing commensals; ↑pro‐inflammatory outputs), shifting circulating metabolites (↓SCFAs; ↑LPS, ↑TMAO, ↑PAA) that act at the BBB to increase nonspecific transcytosis, alter transport, and promote astrocyte reactivity, heightening brain vulnerability.
Daniel Cuervo‐Zanatta, Hari Baskar Balasubramanian, Amir Pasokh, Marietta Zille   +3 more
wiley   +1 more source

Report of the Council of the University of the Cape of Good Hope eighteen ninety three

, 2015
Report of the proceedings of the University of the Cape of Good Hope during 1893.Official 1893 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.

core  

Integrating Leg-Press Strength and Nutritional Status Improves 16-Year Mortality Risk Stratification in General Older Adults. [PDF]

J Cachexia Sarcopenia Muscle
Du Y, Okazaki T, Li X, Obata K, Suzuki N, Miura T, Miyagi M, Nagatomi R, Kogure M, Nakaya N, Hozawa A, Ebihara S.   +11 more
europepmc   +1 more source

An epithelial GPR35 isoform supports tumor‐associated transcriptional and metabolic phenotypes

FEBS Letters, EarlyView.
GPR35 generates two functionally distinct isoforms with previously unresolved roles. GPR35‐short mediates immune‐cell chemotaxis, while GPR35‐long is enriched in colorectal cancer epithelium, where it supports increased metabolism, proliferation, and tumor‐associated transcriptional programs.
Jørgen D. Rønneberg, Martine Hjeltnes, Josephine Krieger, Joshua E. Elias, Maria Stensland, Kristian Holm, Xiaojun Jiang, Chuki Khangsar, Tuula A. Nyman, Arthur Kaser, Johannes R. Hov, Tom H. Karlsen, Nicole C. Kaneider, Frode L. Jahnsen, Georg Schneditz   +14 more
wiley   +1 more source

Report of the Council of the University of the Cape of Good Hope eighteen ninety

, 2015
Report of the proceedings of the University of the Cape of Good Hope during the year 1890. Including a statement of the receipts and expenditure of the University.Official 1890 Report of the Council of the University of the Cape of Good Hope to the Cape ...

core  

Recentering Resource-Based Livelihoods: Prosperity Beyond Extractivism and Pastoralism. [PDF]

Can Rev Sociol
Curley E.
europepmc   +1 more source

Structure‐forward targeting of claudins with synthetic binders

FEBS Letters, EarlyView.
Claudins form the paracellular barriers between epithelial and endothelial tissues at tight junctions and are targets for molecular binders with the goal of modulating barrier permeability. Claudin‐binding molecules are relevant in drug delivery or in altering claudin interactions with disease‐causing proteins.
Alex J. Vecchio
wiley   +1 more source

Report of the Council of the University of the Cape of Good Hope eighteen ninety four

, 2015
Report of the proceedings of the University of the Cape of Good Hope during 1894.Official 1894 Report of the Council of the University of the Cape of Good Hope to the Cape Colonial Parliament.

core  

Comparison of two self-reported tools for assessment of sleep quality. [PDF]

Patient Relat Outcome Meas
Benton MJ, Hutchins AM.
europepmc   +1 more source

Discerning protein pools by selective staining with self‐labeling tags

FEBS Letters, EarlyView.
Cell surface proteins have an intra‐ and extracellular pool. Combining genetic fusion to self‐labeling tags that can be addressed with small molecule fluorophores allows separating these pools. We highlight recent developments and techniques for state‐of‐the‐art interrogation of cell surface proteins in the complex tissue setting.
Kati Fischermanns, Johannes Broichhagen
wiley   +1 more source