Results 191 to 200 of about 17,288,194 (314)

Seven core qualities of good vs. bad play? A principal component analysis of 504 children's play memories and development of a Play Qualities Inventory. [PDF]

Front Psychol
Lieberoth A, Strand P, Lehrmann A, Skovbjerg HM, Jørgensen HH, Jensen JO, Hansen JH, Sand AL, Roepstorff A.   +8 more
europepmc   +1 more source

The PI3Kδ inhibitor roginolisib (IOA‐244) preserves T‐cell function and activity

Molecular Oncology, EarlyView.
Identification of novel PI3K inhibitors with limited immune‐related adverse effects is highly sought after. We found that roginolisib and idelalisib inhibit chronic lymphocytic leukemia (CLL) cells and Treg suppressive functions to similar extents, but roginolisib affects cytotoxic T‐cell function and promotion of pro‐inflammatory T helper subsets to a
Elise Solli, Alessio Bevilacqua, Mathias Wenes, Denis Migliorini, Lars van der Veen, Sigrid S Skånland, Giusy Di Conza, Kjetil Taskén   +7 more
wiley   +1 more source

Not coping with stress and screen-time: mixed methods. [PDF]

Int J Circumpolar Health
Gardarsdottir A, Bender SS.
europepmc   +1 more source

Tumour–host interactions in Drosophila: mechanisms in the tumour micro‐ and macroenvironment

Molecular Oncology, EarlyView.
This review examines how tumour–host crosstalk takes place at multiple levels of biological organisation, from local cell competition and immune crosstalk to organism‐wide metabolic and physiological collapse. Here, we integrate findings from Drosophila melanogaster studies that reveal conserved mechanisms through which tumours hijack host systems to ...
José Teles‐Reis, Tor Erik Rusten
wiley   +1 more source

Remaining caries-free - a personal concern: an interview study to capture the impact of salutogenic influencing factors in caries-free middle-aged adults. [PDF]

BMC Oral Health
Fabricius C, Alvenfors A, Lingström P, Almståhl A, Bernson J.   +4 more
europepmc   +1 more source

Circular RNA expression landscapes in myelodysplastic neoplasms: Associations with mutational signatures and disease progression

Molecular Oncology, EarlyView.
In this explorative study, the abundance of circular RNA molecules in bone marrow stem cells was found to be elevated in patients with high‐risk myelodysplastic neoplasms, and to be associated with an increased risk of progression to acute myeloid leukemia.
Eileen Wedge, Morten Tulstrup, Gabriele Todisco, Pedro Moura, Christophe Côme, Jakob Werner Hansen, Jakob Schmidt Jespersen, Balthasar Schlotmann, Maria Creignou, Mette Dahl, Claudia Schöllkopf, Klas Raaschou‐Jensen, Krister Wennerberg, Bo Porse, Joachim Weischenfeldt, Eva Hellström‐Lindberg, Lasse Sommer Kristensen, Kirsten Grønbæk   +17 more
wiley   +1 more source

Ultra-low-dose cone-beam CT for cleft and craniofacial deformity surgery: radiation reduction and clinical applicability. [PDF]

Maxillofac Plast Reconstr Surg
Mäntynen P, Koivisto J, Leikola J, Kaasalainen T, Sipos N, Heliövaara A, Horelli J, Wolff J, Lusila N, Suojanen J.   +9 more
europepmc   +1 more source

Good publications need good research

Journal of Ayurveda and Integrative Medicine, 2015
openaire   +4 more sources

Colorectal cancer‐derived FGF19 is a metabolically active serum biomarker that exerts enteroendocrine effects on mouse liver

Molecular Oncology, EarlyView.
Meta‐transcriptome analysis identified FGF19 as a peptide enteroendocrine hormone associated with colorectal cancer prognosis. In vivo xenograft models showed release of FGF19 into the blood at levels that correlated with tumor volumes. Tumoral‐FGF19 altered murine liver metabolism through FGFR4, thereby reducing bile acid synthesis and increasing ...
Jordan M. Beardsley, Michael W. Rohr, Joseph A. Goode, Sai Preethi Nakkina, Jignesh G. Parikh, Deborah A. Altomare   +5 more
wiley   +1 more source

A multigene model for response stratification to neoadjuvant chemotherapy in triple negative breast cancer. [PDF]

Breast
van den Ende NS, Smid M, Martens JWM, Debets R, Jager A, van Deurzen CHM.   +5 more
europepmc   +1 more source