Results 281 to 290 of about 2,350,416 (333)
FEBS Open Bio, EarlyView.Metformin mediates mitochondrial quality control in Leber's hereditary optic neuropathy (LHON) fibroblasts carrying mtDNA mutations. At therapeutic levels, metformin activates AMPK signaling to restore mitochondrial dynamics by promoting fusion and restraining fission, while preserving mitochondrial mass, enhancing autophagy/mitophagy and biogenesis ...
Chatnapa Panusatid +3 more
wiley +1 more source
FEBS Open Bio, EarlyView.We investigated the toxicity of 12 active compounds commonly found in herbal weight loss supplements (WLS) using human liver and colon cell models. Epigallocatechin‐3‐gallate was the only compound showing significant toxicity. Metabolic profiling revealed protein degradation, disrupted energy and lipid metabolism suggesting that the inclusion of EGCG ...
Emily C. Davies +3 more
wiley +1 more source
Good Practice Guide for Hospital and Clinical Department of Ophthalmology
, 2016 Maria Rossana Almeida [UNIFESP] Traverso
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Good clinical trials and good clinical practice.
Revista portuguesa de cardiologia : orgao oficial da Sociedade Portuguesa de Cardiologia = Portuguese journal of cardiology : an official journal of the Portuguese Society of Cardiology, 1993 openaire +1 more source
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IS GOOD CLINICAL RESEARCH PRACTICE FOR CLINICAL TRIALS GOOD CLINICAL PRACTICE?
International Journal of Geriatric Psychiatry, 1997This article presents results of monitoring of the recruitment process for a phase III study of a new antidepressant drug in elderly patients with depressive disorders, focusing on the peculiarities of recruitment posed by the presence of comorbidity and coadministration of medications.
O, Yastrubetskaya, E, Chiu, S, O'Connell
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2014
Klinisch geneesmiddelenonderzoek moet uitgevoerd worden volgens het strikte richtsnoer van good clinical practice (GCP). Dit is een internationale ethische en wetenschappelijke kwaliteitsstandaard voor het opzetten, uitvoeren, vastleggen en rapporteren van klinisch geneesmiddelenonderzoek waaraan proefpersonen deelnemen. In dit hoofdstuk beschrijven we
+4 more sources
Klinisch geneesmiddelenonderzoek moet uitgevoerd worden volgens het strikte richtsnoer van good clinical practice (GCP). Dit is een internationale ethische en wetenschappelijke kwaliteitsstandaard voor het opzetten, uitvoeren, vastleggen en rapporteren van klinisch geneesmiddelenonderzoek waaraan proefpersonen deelnemen. In dit hoofdstuk beschrijven we
+4 more sources
Der Urologe A, 2000
The term Good Clinical Practice (GCP) suggests that it relates to a standard of practical clinical medicine; it does not. It is a standard, or more precisely, a set of standards that have been developed for the conduct of clinical trials with investigative new drugs. These standards can actually be applied to any experimentation in humans.
Jean Soul-Lawton, Ria Kroon
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The term Good Clinical Practice (GCP) suggests that it relates to a standard of practical clinical medicine; it does not. It is a standard, or more precisely, a set of standards that have been developed for the conduct of clinical trials with investigative new drugs. These standards can actually be applied to any experimentation in humans.
Jean Soul-Lawton, Ria Kroon
openaire +2 more sources
2010
Good Clinical Practice (GCP) is an internationally recognized standard governing the ethical and scientific quality for the design, conduct, recording and reporting of clinical trials involving human subjects. While full compliance with each of the principles of ICH GCP is not mandatory for the conduct of cosmetic studies, the spirit of GCP should be ...
Mamoru Narukawa, Masahiro Takeuchi
+5 more sources
Good Clinical Practice (GCP) is an internationally recognized standard governing the ethical and scientific quality for the design, conduct, recording and reporting of clinical trials involving human subjects. While full compliance with each of the principles of ICH GCP is not mandatory for the conduct of cosmetic studies, the spirit of GCP should be ...
Mamoru Narukawa, Masahiro Takeuchi
+5 more sources
European Journal of Clinical Microbiology & Infectious Diseases, 1990
Good Clinical Practice (GCP) is a quality assurance system dealing with all stages of clinical trials which is progressively being adopted by European countries. European GCP guidelines are in preparation and will be issued soon. However, implementation of the guidelines poses major and costly problems.
openaire +2 more sources
Good Clinical Practice (GCP) is a quality assurance system dealing with all stages of clinical trials which is progressively being adopted by European countries. European GCP guidelines are in preparation and will be issued soon. However, implementation of the guidelines poses major and costly problems.
openaire +2 more sources