Results 41 to 50 of about 1,702,112 (292)

Deep Sequencing of FLT3‐ITD Enables Response Evaluation and Post‐Treatment Monitoring in Childhood AML: An Exploratory Study

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background An internal tandem duplication in the gene encoding Fms‐like tyrosine kinase 3 (FLT3‐ITD) is associated with high relapse risk and poor prognosis in acute myeloid leukemia (AML) and plays a crucial role in treatment decisions. Measurable residual disease (MRD) analysis of FLT3‐ITD during and after treatment has shown prognostic ...
Sofie Johansson Alm   +11 more
wiley   +1 more source

Aqueous extract of Enantia chlorantha Oliv. demonstrates antimalarial activity and improves redox imbalance and biochemical alterations in mice

open access: yesBMC Complementary Medicine and Therapies
Background Malaria is an infectious disease, which has continued to cause inconceivable loss of lives every year, almost unabatedly. Currently, it has become more difficult to treat the disease due to the emergence and spread of resistance to recommended
Ikponmwosa Owen Evbuomwan   +2 more
doaj   +1 more source

Exploring the Effectiveness of Hydrophobic Glass Surface on Touch-Enabled Digital Device to Reduce Microbial Adhesion and Propagation

open access: yesJournal of Pharmacy and Bioallied Sciences
This study investigates the effectiveness of hydrophobic glass surfaces in reducing microbial populations on touch-enabled digital devices. Hydrophobic coatings have been proposed as a potential solution to minimize microbial adhesion and growth on ...
Premkumar Sowmya Vithya   +1 more
doaj   +1 more source

Claudin‐6 Protein Expression in Atypical Teratoid/Rhabdoid Tumors Is Strongly Enriched in the Molecular Subgroup AT/RT‐TYR

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Claudin‐6 has emerged as a promising immunotherapeutic target, yet protein‐level data in atypical teratoid/rhabdoid tumors (AT/RTs) have been inconsistent. We analyzed 36 well‐characterized AT/RT samples and found membranous claudin‐6 protein expression in 58% of cases, with striking enrichment in the molecular subgroup AT/RT‐TYR (100%) and ...
Victoria E. Fincke   +4 more
wiley   +1 more source

ESKAPE Pathogens in Hospitalized Patients: A Comprehensive Profiling of Infections and Characteristics at Universitas Airlangga Hospital, Surabaya, Indonesia

open access: yesMajalah Biomorfologi
Highlights • This study found that ESKAPE pathogenic infections at Universitas Airlangga Hospital were dominated by Gram-negative bacteria, particularly Klebsiella pneumoniae, with sputum as the most commonly collected specimen providing valuable data ...
Dinda Rachma Harlisa   +3 more
doaj   +1 more source

Attitudes of Indonesian Medical Doctors and Medical Students Toward Genome Editing

open access: yesJournal of Multidisciplinary Healthcare, 2021
Safira Nur Izzah,1 Dimas Setyanto,1 Nurina Hasanatuludhhiyah,2,3 Danti Nur Indiastuti,2,3 Zamal Nasution,4 Annette d’Arqom2,3 1Faculty of Medicine, Universitas Airlangga, Surabaya, Indonesia; 2Division of Pharmacology and Therapy, Department of ...
Izzah SN   +5 more
doaj  

Bibliometric Study of Microwave-Assisted Synthesis of Flavanone Derivatives

open access: yesBorneo Journal of Pharmacy, 2023
This study aims to describe various studies related to synthesizing flavanone derivatives using the microwave-assisted method with a bibliometric approach. Metadata information was collected from Scopus on June 30th, 2023, with three keywords (microwave-
Hadi Poerwono, Marcellino Rudyanto
doaj   +1 more source

Time Toxicity in Wilms Tumor: Quantifying the Burden of Healthcare Interaction in the First Year After Diagnosis

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Background Wilms tumor (WT) treatment imposes a significant time burden on patients and their families. Time toxicity is a patient‐centered metric that quantifies the burden of healthcare interaction. We sought to define time toxicity in the first year after diagnosis of WT and hypothesized that it would increase as tumor stage and treatment ...
Caleb Q. Ashbrook   +6 more
wiley   +1 more source

The Warwick-Edinburgh Mental Well-being Scale (WEMWBS) : development and UK validation [PDF]

open access: yes, 2007
Background There is increasing international interest in the concept of mental well-being and its contribution to all aspects of human life. Demand for instruments to monitor mental well-being at a population level and evaluate mental health promotion ...
Louise Hiller   +45 more
core   +1 more source

Emapalumab for Immune Effector Cell‐Associated Hemophagocytic Lymphohistiocytosis‐Like Syndrome Following CD19‐Directed CAR‐T in Two Patients With B‐ALL: Clinical and Biomarker Correlates

open access: yesPediatric Blood &Cancer, EarlyView.
ABSTRACT Immune effector cell‐associated hemophagocytic lymphohistiocytosis‐like syndrome (IEC‐HS) is a life‐threatening hyperinflammatory toxicity distinct from cytokine release syndrome (CRS) and neurotoxicity following chimeric antigen receptor T‐cell (CAR‐T) therapy. In a single‐institution retrospective cohort of pediatric and young adult patients
Thomas J. Galletta   +6 more
wiley   +1 more source

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