Results 51 to 60 of about 8,536,940 (156)

Development of a nalmefene formulation suitable for a community‐use auto‐injector

British Journal of Clinical Pharmacology, EarlyView.
Aim Time to onset of reversal is critical when treating opioid‐induced respiratory depression and hypoxia. This study aimed to develop a formulation of the opioid antagonist nalmefene with an increased absorption rate and reduced time to onset of reversal following intramuscular administration. Methods Several absorption enhancers were screened in rats,
Alessandra Cipriano, Manjunath S. Shet, Hugh Huang, Ronnie Ortiz, Garth T. Whiteside, Glen Apseloff, Stephen C. Harris   +6 more
wiley   +1 more source

Need for good pharmacy practice compliance in community pharmacies of nepal: its challenges and opportunities

Discover Public Health
Community pharmacies in Nepal serve as vital access points for healthcare services and medication. However, compliance with Good Pharmacy Practice (GPP) standards remains suboptimal despite the existence of national guidelines and regulatory frameworks ...
Sabina Sankhi, Nirmal Raj Marasine
doaj   +1 more source

Driving Circularity Upstream: The Mediating Role of Circular Supply Chain Management in Environmental Performance

Business Strategy and the Environment, EarlyView.
ABSTRACT The transition toward a circular economy has gained growing prominence as a means to reduce supply chain waste and enhance environmental performance, yet its success ultimately depends on effective collaboration among supply chain partners. This study aims to explore the factors that influence the adoption of circular practices in the upstream
Noelia Garcia‐Buendia, José Moyano‐Fuentes, Juan Manuel Maqueira‐Marín, Verónica León‐Bravo, Federico Caniato   +4 more
wiley   +1 more source

Introduction of standards of good pharmacy practice (GPP) in the world [PDF]

, 2017
Останніми роками в міжнародній аптечній практиці проходять активні процеси, що направлені на підвищення якості професійної діяльності, зокрема запроваджуються стандарти Належної аптечної практики (GPP).
Прилипко, Н. А., Prylypko, N. A., Бєляєва, О. І., Vyshnytska, I. V., Вишницька, І. В., Унгурян, Л. М., Unhurian, L. M., Bielyaieva, O. I.   +7 more
core  

Drug dispensing practices in private pharmacies in Goa

National Journal of Physiology, Pharmacy and Pharmacology, 2018
Background: In India, patients self-order both over-the-counter and prescription-only drugs in pharmacies, although the dispensing of the latter without a prescription is unlawful.
Mysia Rachel Paes, Sunita De Sa
doaj   +1 more source

Exposure‐Response Analyses of Datopotamab Deruxtecan (Dato‐DXd), a TROP2‐Directed Antibody‐Drug Conjugate, in Advanced Non‐small Cell Lung Cancer

Clinical Pharmacology &Therapeutics, EarlyView.
Exposure‐response analyses supported a favorable benefit‐risk profile of Dato‐DXd at 6 mg/kg Q3W in patients with advanced nonsquamous NSCLC. Datopotamab deruxtecan (Dato‐DXd) is a trophoblast cell‐surface antigen‐2 (TROP2)‐directed antibody‐drug conjugate (ADC) that has demonstrated clinical activity in patients with NSCLC who have received prior ...
Ying Hong, Anna M. Mc Laughlin, Yuzhuo Pan, Sofia Friberg Hietala, Sophie Peigné, Michael Chargualaf, Zoey Tang, Diansong Zhou, Naoyuki Tajima, Malaz Abutarif, Tushar Garimella   +10 more
wiley   +1 more source

Pharmacy practice in hyperdiverse, urban communities: perspectives of independent community pharmacists in East and South-East London [PDF]

This study considers pharmacy practice in hyperdiverse, urban communities through the eyes of independent community pharmacists, who are underrepresented figures in anthropological research.
Duckett, Kathryn
core   +1 more source

Risk of hostility and aggression with perampanel monotherapy versus combination therapy in pediatric epilepsy: A Japanese post‐marketing database study using a nested case–control design

Epileptic Disorders, EarlyView.
Abstract Objective To compare the incidence of hostility‐ and aggression‐related adverse events in children with focal‐onset seizures (FOS), with or without focal to bilateral tonic–clonic seizures (FBTCS), receiving perampanel as monotherapy or in combination with other antiseizure medications (ASMs).
Yukitoshi Takahashi, Masato Takeuchi, Akiko Yoshimura, Kasumi Daidoji, Kazuhiro Matsutani, Mika Ishii   +5 more
wiley   +1 more source

Prolonged fenfluramine use in open‐label studies of Dravet or Lennox–Gastaut syndromes: Long‐term safety, tolerability, patient global functioning, and considerations for interpreting effectiveness

Epilepsia, EarlyView.
This graphical abstract provides an overview of the content from this open‐label extension study of fenfluramine use in patients with Dravet syndrome or Lennox‐Gastaut syndrome. Abstract Objective Long‐term safety and global functioning are reported in patients with Dravet syndrome (DS) or Lennox–Gastaut syndrome (LGS) treated with fenfluramine in an ...
Antonio Gil‐Nagel, Kelly G. Knupp, Boudewijn Gunning, Domenica Immacolata Battaglia, Elizabeth A. Thiele, Ingrid E. Scheffer, An‐Sofie Schoonjans, Rima Nabbout, Nathalie Villeneuve, Kerstin Alexandra Klotz, Nicola Specchio, Rocio Sanchez‐Carpintero, Marta Zolnowska, Anne‐Liv Schulz, Lily Perrin, Najla Dickson, Mélanie Langlois, Amélie Lothe, Joseph Sullivan   +18 more
wiley   +1 more source

Changes in effectiveness and safety in patients with Lennox–Gastaut syndrome transitioning from the fenfluramine randomized controlled trial to open‐label extension study

Epilepsia Open, EarlyView.
This graphical abstract provides an overview of the content from this post hoc analysis describing the trajectories of fenfluramine effectiveness and safety, along with dose changes over time, in patients with Lennox‐Gastaut syndrome. Abstract In the phase 3 randomized controlled trial (RCT; NCT03355209) of fenfluramine in Lennox–Gastaut syndrome (LGS),
Rima Nabbout, Orrin Devinsky, Lieven Lagae, Ingrid E. Scheffer, Renzo Guerrini, Joseph Sullivan, Antonio Gil‐Nagel, Sameer M. Zuberi, Kate Riney, Patrick Healy, Jayne Abraham, Rebecca Zhang Roper, Mélanie Langlois, Amélie Lothe, Kelly G. Knupp   +14 more
wiley   +1 more source