Results 111 to 120 of about 569,411 (259)
FEBS Open Bio, EarlyView.Enzymes of the 2‐hydroxyacyl‐CoA lyase group catalyze the condensation of formyl‐CoA with aldehydes or ketones. Thus, by structural adaptation of active sites, practically any pharmaceutically and industrially important 2‐hydroxyacid could be biotechnologically synthesized. Combining crystal structure analysis, active site mutations and kinetic assays,
Michael Zahn +4 more
wiley +1 more source
Goodness-of-fit testing for regime-switching models [PDF]
In this paper we propose a novel goodness-of-fit testing scheme for regime-switching models. We consider models with an observable, as well as, a latent state process.
Janczura, Joanna, Weron, Rafal
core +1 more source
Goodness of fit test for uniform distribution with censored observation. [PDF]
J Korean Stat Soc, 2023 Sreedevi EP, Kattumannil SK.
europepmc +1 more source
FEBS Open Bio, EarlyView.Time‐resolved X‐ray solution scattering captures how proteins change shape in real time under near‐native conditions. This article presents a practical workflow for light‐triggered TR‐XSS experiments, from data collection to structural refinement. Using a calcium‐transporting membrane protein as an example, the approach can be broadly applied to study ...
Fatemeh Sabzian‐Molaei +3 more
wiley +1 more source
Goodness-of-Fit Tests via Entropy-Based Density Estimation Techniques
StatsGoodness-of-fit testing remains a fundamental problem in statistical inference with broad practical importance. In this paper, we introduce two new goodness-of-fit tests grounded in entropy-based density estimation techniques.
Luai Al-Labadi, Ruodie Yu, Kairui Bao
doaj +1 more source
FEBS Open Bio, EarlyView.In this study, we developed a deep learning method for mitotic figure counting in H&E‐stained whole‐slide images and evaluated its prognostic impact in 13 external validation cohorts from seven different cancer types. Patients with more mitotic figures per mm2 had significantly worse patient outcome in all the studied cancer types except colorectal ...
Joakim Kalsnes +32 more
wiley +1 more source
THE PROPERTIES OF SOME GOODNESS-OF-FIT TESTS [PDF]
The properties of Pearson’s goodness-of-fit test, as used in density forecast evaluation, income distribution analysis and elsewhere, are analysed. The components-of-chi-squared or “Pearson analog” tests of Anderson (1994) are shown to be less generally ...
Boero, Gianna +2 more
core
Goodness of fit tests for random multigraph models. [PDF]
J Appl Stat, 2023 Shafie T.
europepmc +1 more source
Tracking Motor Progression and Device‐Aided Therapy Eligibility in Parkinson's Disease
Annals of Clinical and Translational Neurology, EarlyView.ABSTRACT Objective To characterise the progression of motor symptoms and identify eligibility for device‐aided therapies in Parkinson's disease, using both the 5‐2‐1 criteria and a refined clinical definition, while examining differences across genetic subgroups.
David Ledingham +7 more
wiley +1 more source
Tangent exponential-G family of distributions with applications in medical and engineering
Alexandria Engineering JournalThis study introduces a novel family of probability distributions called the ”tangent exponential-G family,” which is derived using trigonometric transformations of the exponential distribution.
Eslam Hussam +2 more
doaj +1 more source