Results 61 to 70 of about 375,535 (333)

In situ molecular organization and heterogeneity of the Legionella Dot/Icm T4SS

open access: yesFEBS Letters, EarlyView.
We present a nearly complete in situ model of the Legionella Dot/Icm type IV secretion system, revealing its central secretion channel and identifying new components. Using cryo‐electron tomography with AI‐based modeling, our work highlights the structure, variability, and mechanism of this complex nanomachine, advancing understanding of bacterial ...
Przemysław Dutka   +11 more
wiley   +1 more source

Improved EDF-Based Tests for Weibull Distribution Using Ranked Set Sampling

open access: yesMathematics, 2022
It is well known that ranked set sampling (RSS) is superior to conventional simple random sampling (SRS) in that it frequently results in more effective inference techniques.
Safar M. Alghamdi   +5 more
doaj   +1 more source

Two-dimensional Kolmogorov-type Goodness-of-fit Tests Based on Characterizations and their Asymptotic Efficiencies

open access: yes, 2015
In this paper new two-dimensional goodness of fit tests are proposed. They are of supremum-type and are based on different types of characterizations. For the first time a characterization based on independence of two statistics is used for goodness-of ...
Milošević, Bojana, Obradović, Marko
core   +1 more source

Diversity and complexity in neural organoids

open access: yesFEBS Letters, EarlyView.
Neural organoid research aims to expand genetic diversity on one side and increase tissue complexity on the other. Chimeroids integrate multiple donor genomes within single organoids. Self‐organising multi‐identity organoids, exogenous cell seeding, or enforced assembly of region‐specific organoids contribute to tissue complexity.
Ilaria Chiaradia, Madeline A. Lancaster
wiley   +1 more source

Goodness-of-fit tests in many dimensions

open access: yes, 2004
A method is presented to construct goodness-of-fit statistics in many dimensions for which the distribution of all possible test results in the limit of an infinite number of data becomes Gaussian if also the number of dimensions becomes infinite ...
A. van Hameren   +5 more
core   +1 more source

Degree-based goodness-of-fit tests for heterogeneous random graph models : independent and exchangeable cases [PDF]

open access: yes, 2019
The degrees are a classical and relevant way to study the topology of a network. They can be used to assess the goodness-of-fit for a given random graph model. In this paper we introduce goodness-of-fit tests for two classes of models. First, we consider
Billingsley P.   +9 more
core   +2 more sources

Transcriptional network analysis of PTEN‐protein‐deficient prostate tumors reveals robust stromal reprogramming and signs of senescent paracrine communication

open access: yesMolecular Oncology, EarlyView.
Combining PTEN protein assessment and transcriptomic profiling of prostate tumors, we uncovered a network enriched in senescence and extracellular matrix (ECM) programs associated with PTEN loss and conserved in a mouse model. We show that PTEN‐deficient cells trigger paracrine remodeling of the surrounding stroma and this information could help ...
Ivana Rondon‐Lorefice   +16 more
wiley   +1 more source

Goodness-of-Fit Tests for COM-Poisson Distribution Using Stein's Characterization

open access: yesAustrian Journal of Statistics
A crucial part of data analysis is to assess the adequacy of the fit of the probability models used, and such assessment is generally made using the goodness-of-fit tests.
Traison T, V S Vaidyanathan
doaj   +1 more source

Infrared laser sampling of low volumes combined with shotgun lipidomics reveals lipid markers in palatine tonsil carcinoma

open access: yesMolecular Oncology, EarlyView.
Nanosecond infrared laser (NIRL) low‐volume sampling combined with shotgun lipidomics uncovers distinct lipidome alterations in oropharyngeal squamous cell carcinoma (OPSCC) of the palatine tonsil. Several lipid species consistently differentiate tumor from healthy tissue, highlighting their potential as diagnostic markers.
Leonard Kerkhoff   +11 more
wiley   +1 more source

Goodness-of-fit tests for multi-dimensional copulas: Expanding application to historical drought data

open access: yesWater Science and Engineering, 2013
The question of how to choose a copula model that best fits a given dataset is a predominant limitation of the copula approach, and the present study aims to investigate the techniques of goodness-of-fit tests for multi-dimensional copulas. A goodness-of-
Ming-wei Ma   +4 more
doaj   +1 more source

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