Results 61 to 70 of about 102,684 (297)

CCDC80 suppresses high‐grade serous ovarian cancer migration via negative regulation of B7‐H3

Molecular Oncology, EarlyView.
PAX8 is a lineage‐specific master regulator of transcription in high‐grade serous ovarian cancer (HGSC) progression. We show for the first time that PAX8 facilitates proliferation and metastasis by repressing the cell autonomous tumor suppressor CCDC80 and inducing B7‐H3 expression.
Aya Saleh, Nitzan Medina‐Itzhaki, Milena Chekov, Eden Gal‐Swisa, Roba Gabesh‐Wahabi, Inbar Savyon, Inna Naroditsky, Hilary A. Kenny, Basem Fares, Lina Korsensky, Einav Girsh, Liron Berger, Ruth Perets   +12 more
wiley   +1 more source

Appendix C. Goodness-of-fit tests.

, 2016
Goodness-of-fit ...
Alexis Avril (589844), Roger Pradel (111017), Dominique Pontier (163631), Hugues Santin-Janin (516257), Jérôme Letty (822520), Yves Léonard (2924190)   +5 more
core   +1 more source

A best-fit probability distribution for the estimation of rainfall in northern regions of Pakistan

Open Life Sciences, 2016
This study was designed to find the best-fit probability distribution of annual maximum rainfall based on a twenty-four-hour sample in the northern regions of Pakistan using four probability distributions: normal, log-normal, log-Pearson type-III and ...
Amin M. T., Rizwan M., Alazba A. A.
doaj   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Goodness of fit tests and indices.

, 2016
Goodness of fit tests and indices.
Renate L. E. P. Reniers (2622055), Ashleigh Lin (2622058), Laura Murphy (560163), Sandra Para Bartolomé (2622052), Stephen J. Wood (468632)   +4 more
core   +1 more source

Conditional Goodness-of-Fit Tests for Discrete Distributions [PDF]

, 2022
In this paper, we address the problem of testing goodness-of-fit for discrete distributions, where we focus on the geometric distribution. We define new likelihood-based goodness-of-fit tests using the beta-geometric distribution and the type I discrete ...
Lindqvist, Bo Henry, Erlemann, Rasmus
core   +1 more source

The use of Weibull Statistics to Quantify Property Variability in Fe-3Mn-0.8C Sinter-Hardened Structurally Inhomogeneous Steels

Archives of Metallurgy and Materials, 2013
Aby uzyskać trzy warianty spiekanej stali Fe-3Mn-0.8C wytworzono mieszanki proszków: niskowęglowego żelazoman- ganu. grafitu oraz proszków żelaza firmy Hóganiis: gąbczastego - NC100.24 i rozpylanych - ABC 100.30 oraz ASC 100.29.
Cias A., Czarski A.
doaj   +1 more source

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Interpreting the effects of DNA polymerase variants at the structural level

Molecular Oncology, EarlyView.
Using MAVISp and molecular dynamics simulations, we analyzed over 60 000 missense variants in POLE and POLD1 from ClinVar, COSMIC, cBioPortal, and saturation mutagenesis. Identified mechanistic indicators, including stability, binding, and long‐range, enable structural interpretation, providing ACMG‐like evidence for possible reclassification of VUS ...
Matteo Arnaudi, Karolina Krzesińska, Ludovica Beltrame, Pablo Sánchez‐Izquierdo Besora, Matteo Tiberti, Mef Nilbert, Anna Rohlin, Elena Papaleo   +7 more
wiley   +1 more source

Exact goodness-of-fit tests for censored dats [PDF]

, 2009
The statistic introduced in Fortiana and Grané (2003) is modified so that it can be used to test the goodness-of-fit of a censored sample, when the distribution function is fully specified.
Grané, Aurea, Grané Chávez, Aurea
core