Results 101 to 110 of about 755,302 (276)
Activation of the mitochondrial protein OXR1 increases pSyn129 αSynuclein aggregation by lowering ATP levels and altering mitochondrial membrane potential, particularly in response to MSA‐derived fibrils. In contrast, ablation of the ER protein EMC4 enhances autophagic flux and lysosomal clearance, broadly reducing α‐synuclein aggregates.
Sandesh Neupane +11 more
wiley +1 more source
Neyman smooth-type goodness-of-fit tests in complex surveys
In this study, we extend Neyman smooth-type goodness-of-fit tests to complex survey settings involving categorical data, by incorporating design-consistent estimators under the survey framework.
Yan Lu +3 more
doaj +1 more source
Bioscience students were asked for their opinions on the value and teaching of skills. 204 responded that teamwork, time management and study skills are necessary to reach University, that scientific writing, research, laboratory and presentation skills are taught effectively during their studies, while other skills are gained inherently through study ...
Janella Borrell, Susan Crennell
wiley +1 more source
Goodness-of-Fit Test for the Bivariate Negative Binomial Distribution
When modeling real-world data, we face the challenge of determining which probability distribution best represents the data. To address this intricate problem, we rely on goodness-of-fit tests.
Francisco Novoa-Muñoz +1 more
doaj +1 more source
Goodness-of-fit testing for meta-analysis of rare binary events. [PDF]
Zhang M, Xiao OY, Lim J, Wang X.
europepmc +1 more source
Why human connection is the true metric of research success
Human‐centred mentorship can be shaped by mentor attributes, actions, intrinsic drive and career ambition. Drawing on reflections across Singapore and France, as well as workshop insights from FEBS‐IUBMB ENABLE 2024, this article shows that human‐centred mentorship creates the conditions for sustainable growth, well‐being and retention in research ...
Timothy Lin Yun Tan +3 more
wiley +1 more source
Optimizing photoactivation of PA‐mCherry for optical pooled CRISPR screens
Photoactivatable PA‐mCherry finds widespread use to optically tag individual cells. However, confocal 405 nm UV laser‐scanning (normal scan) is much less efficient than widefield UV illumination, limiting the use of PA‐mCherry on confocal instruments. We remedy this limitation by reporting that rapid and repeated confocal scanning with a low‐intensity,
Sravasti Mukherjee +3 more
wiley +1 more source
Goodness-of-Fit Tests via Entropy-Based Density Estimation Techniques
Goodness-of-fit testing remains a fundamental problem in statistical inference with broad practical importance. In this paper, we introduce two new goodness-of-fit tests grounded in entropy-based density estimation techniques.
Luai Al-Labadi, Ruodie Yu, Kairui Bao
doaj +1 more source
Goodness of fit test for uniform distribution with censored observation. [PDF]
Sreedevi EP, Kattumannil SK.
europepmc +1 more source
THE PROPERTIES OF SOME GOODNESS-OF-FIT TESTS [PDF]
The properties of Pearson’s goodness-of-fit test, as used in density forecast evaluation, income distribution analysis and elsewhere, are analysed. The components-of-chi-squared or “Pearson analog” tests of Anderson (1994) are shown to be less generally ...
Boero, Gianna +2 more
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