Results 111 to 120 of about 173,528,053 (291)

Dose‐dependent hepatotoxicity of hydrogen peroxide in HepG2 cells and its modulation by CYP450 induction

open access: yesFEBS Open Bio, EarlyView.
NMR metabolomics revealed concentration‐dependent metabolic perturbations in HepG2 cells exposed to H2O2. Rifampicin pretreatment enhanced metabolic competence, attenuated toxin‐induced alterations and produced metabolite profiles more consistent with human liver physiology, supporting the use of CYP450‐induced HepG2 models for improved in vitro ...
Maren Jinks   +4 more
wiley   +1 more source

Use of Multivariate Adaptive Regression Splines (MARS) and Classification and Regression Tree (CART) Data Mining Algorithms to Predict Live Body Weight of Tswana Sheep

open access: yesBiology
This study was conducted to (i) determine the association between live body weight (BW) and biometric traits, (ii) examine the effect of biometric traits on BW of Tswana sheep using MARS and CART data mining algorithms, (iii) compare the performance of ...
Monosi Andries Bolowe   +3 more
doaj   +1 more source

In silico and in vitro exploration of a tyrosinase for biocatalytic production of catechols

open access: yesFEBS Open Bio, EarlyView.
Tyrosinase from Ralstonia pseudosolanacearum is a promising biocatalyst for producing valuable catechols from monophenol substrates. This tyrosinase is uniquely suited to this due to its high monophenolase : diphenolase ratio. We combined in silico docking and in vivo kinetic characterisation of this tyrosinase with 11 industrially relevant monophenols,
James Britton   +6 more
wiley   +1 more source

Styrking av helseberedskap og krisehåndtering – «mismatch» mellom samarbeidet i EU og EØS?

open access: yesInternasjonal Politikk
I EU er helsepolitikk, helseberedskap og krisehåndtering primært et nasjonalt anliggende. Over tid har likevel medlemslandene styrket samarbeidet på disse områdene.
Frode Veggeland, Martin Stangborli Time
doaj   +1 more source

Purification and preparation of Marchantia polymorpha Auxin Response Factor 2 for phase separation studies

open access: yesFEBS Open Bio, EarlyView.
We describe detailed protocols for the purification and preparation of Marchantia polymorpha Auxin Response Factor 2 (MpARF2). This protein is fused to an MBP solubility tag and an mNG fluorescent tag and is purified from Escherichia coli. The presented procedures make it possible to study MpARF2 assemblies, which could arise from phase separation ...
Bas Janssen   +5 more
wiley   +1 more source

Goodness of Fit Test and Test of Independence by Entropy

open access: yesJournal of Mathematical Extension, 2009
To test whether a set of data has a specific distribution or not, we can use the goodness of fit test. This test can be done by one of Pearson X 2 -statistic or the likelihood ratio statistic G 2 , which are asymptotically equal, and also by using
M. Sharifdoost, N. Nematollahi, E. Pasha
doaj  

GelMA‐based 3D spheroids recapitulate transcriptomic and functional hallmarks of myeloid sarcoma

open access: yesFEBS Open Bio, EarlyView.
GelMA 5% hydrogels support the formation of myeloid leukemia spheroids that recapitulate MS‐specific features, including G1 arrest, apoptosis, and ECM‐driven transcriptomic reprogramming. The 3D model mimicked soft‐tissue‐like stiffness and oxygen conditions, and transcriptomic convergence with primary MS samples confirmed its utility as a preclinical ...
Nicolas Germain   +11 more
wiley   +1 more source

Goodness-of-fit statistics for 3 to 5 class solutions.

open access: yes, 2017
Goodness-of-fit statistics for 3 to 5 class solutions.
Dorothea Mayer (3617963)   +6 more
core   +1 more source

Goodness of Fit for Multivariate Linear Regression Models [PDF]

open access: yesThe Egyptian Statistical Journal, 1994
Ahmed Haroun
doaj   +1 more source

Goodness-of-Fit Test for the Bivariate Negative Binomial Distribution

open access: yesAxioms
When modeling real-world data, we face the challenge of determining which probability distribution best represents the data. To address this intricate problem, we rely on goodness-of-fit tests.
Francisco Novoa-Muñoz   +1 more
doaj   +1 more source

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