Results 41 to 50 of about 761,301 (258)
A common goodness-of-fit framework for neural population models using marked point process time-rescaling [PDF]
, 2018 A critical component of any statistical modeling procedure is the ability to assess the goodness-of-fit between a model and observed data. For spike train models of individual neurons, many goodness-of-fit measures rely on the time-rescaling theorem and ...
Arai, Kensuke +3 more
core +1 more source
The role and implications of mammalian cellular circadian entrainment
FEBS Letters, EarlyView.At their most fundamental level, mammalian circadian rhythms occur inside every individual cell. To tell the correct time, cells must align (or ‘entrain’) their circadian rhythm to the external environment. In this review, we highlight how cells entrain to the major circadian cues of light, feeding and temperature, and the implications this has for our
Priya Crosby
wiley +1 more source
An Online Test for Goodness-of-Fit in Logistic Regression Model
IEEE Access, 2019 In past decades, the goodness-of-fit test has been widely used to evaluate the calibration of prediction models. The test helps to determine whether poor predictions (lack of fit) are significant, which would indicate that problems exist in the model ...
Yuke Qiu, Liu Liu, Xin Lai, Yuwen Qiu
doaj +1 more source
Real‐time assay of ribonucleotide reductase activity with a fluorescent RNA aptamer
FEBS Letters, EarlyView.Ribonucleotide reductases (RNR) synthesize DNA building blocks de novo, making them crucial in DNA replication and drug targeting. FLARE introduces the first single‐tube real‐time coupled RNR assay, which enables isothermal tracking of RNR activity at nanomolar enzyme levels and allows the reconstruction of allosteric regulatory patterns and rapid ...
Jacopo De Capitani +4 more
wiley +1 more source
Tailor-made tests for goodness of fit to semiparametric hypotheses [PDF]
, 2006 We introduce a new framework for constructing tests of general semiparametric hypotheses which have nontrivial power on the $n^{-1/2}$ scale in every direction, and can be tailored to put substantial power on alternatives of importance.
Bickel, Peter J. +2 more
core +2 more sources
FEBS Letters, EarlyView.Multidrug transporters BpeB and BpeF from the Gram‐negative pathogen Burkholderia pseudomallei have a hydrophilic patch in their substrate‐binding pocket. Drug susceptibility tests and growth curve analyses using an Escherichia coli recombinant expression system revealed that the hydrophilic patches of BpeB and BpeF are involved in the substrate ...
Ui Okada, Satoshi Murakami
wiley +1 more source
Indonesian Journal of Pharmacy, 2021 The population-based approach has been widely applied to describe the pharmacokinetic profile of many drugs. The aim of this current research was to study the implementation of the population-based pharmacokinetics of levofloxacin in rabbits administered
Akhmad Kharis Nugroho +4 more
doaj +1 more source
Mechanisms of parasite‐mediated disruption of brain vessels
FEBS Letters, EarlyView.Parasites can affect the blood vessels of the brain, often causing serious neurological problems. This review explains how different parasites interact with and disrupt these vessels, what this means for brain health, and why these processes matter. Understanding these mechanisms may help us develop better ways to prevent or treat brain infections in ...
Leonor Loira +3 more
wiley +1 more source
On The Pros and Cons of Using Excel for Regression Analysis
Turkish Journal of Agriculture: Food Science and TechnologyExcel is a useful and powerful software for simple regression analysis without any programming skills and that is why, it is widely preferred by the undergraduate students from various areas such as chemistry, biology and agriculture as well as many ...
Sencer Buzrul
doaj +1 more source
Asymptotically distribution-free goodness-of-fit testing for tail copulas [PDF]
, 2014 Let $(X_1,Y_1),\ldots,(X_n,Y_n)$ be an i.i.d. sample from a bivariate distribution function that lies in the max-domain of attraction of an extreme value distribution.
Can, Sami Umut +3 more
core +3 more sources