Results 21 to 30 of about 697,907 (257)

Prospecting the protein design landscape

open access: yesFEBS Letters, EarlyView.
This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona   +4 more
wiley   +1 more source

Measurement of the Functional Size of Web Analytics Implementation: A COSMIC-Based Case Study Using Machine Learning

open access: yesFuture Internet
To fully leverage Google Analytics and derive actionable insights, web analytics practitioners must go beyond standard implementation and customize the setup for specific functional requirements, which involves additional web development efforts ...
Ammar Abdallah   +4 more
doaj   +1 more source

Utilization of e-book 3-dimensions information systems based on google analytics

open access: yesAl-Ma'mun, 2022
The use of information and communication technology has become a necessity for people to search for information and information published in 3-dimensional e-book media, which has been widely used in information retrieval.
Kamaludin (Mr.) Kamaludin Kamaludin   +3 more
doaj   +1 more source

PAK1 activation drives divergent resistance mechanisms to aromatase inhibition and tamoxifen in a luminal: A breast cancer model

open access: yesMolecular Oncology, EarlyView.
Breast cancer remains a major cause of cancer death in women, frequently developing endocrine therapy resistance. This study demonstrates that upregulated p21‐activated kinase 1 (PAK1) activity drives resistance to tamoxifen and long‐term estrogen deprivation in ER+ breast cancer models.
Luisa Schwarzmüller   +10 more
wiley   +1 more source

Editorial

open access: yesHolos, 2017
A educação, a ciência e a tecnologia brasileira sofre graves cortes em seus orçamentos, bem como desloca os esforços da comunidade acadêmica à luta pela manutenção dos investimentos no presente e no futuro da grande nação brasileira.
José Yvan Pereira Leite
doaj   +1 more source

Challenges of big data adoption in Malaysia SMEs based on Lessig’s modalities: A systematic review

open access: yesCogent Business & Management, 2021
This study aims to review the challenges of implementing big data analytics by Small and Medium Enterprises (SMES) in Malaysia. There is a lack of literature studies examining the relationship between Lessig’s four modalities and the challenges of big ...
Min Hooi Chuah, Ramayah Thurusamry
doaj   +1 more source

Natural Language Processing: Writing Analytics [PDF]

open access: yes, 2022
Writing analytics uses computational techniques to analyse written texts for the purposes of improving learning. This chapter provides an introduction to writing analytics, through the discussion of linguistic and domain orientations to the analysis of
Shibani, A, Gibson, A
core   +1 more source

Hyperosmotic stress‐induced redistribution of pre‐mRNA cleavage factor I subunits is associated with shifts in alternative polyadenylation

open access: yesFEBS Open Bio, EarlyView.
Hyperosmotic stress triggers the relocation of the CFIm complex from the nucleus to the cytoplasm. This shift creates a nuclear ‘stoichiometric bottleneck’, limiting CFIm availability for mRNA processing. Consequently, specific mRNAs like NUDT21 and DICER1 undergo targeted 3′UTR shortening, demonstrating how spatial protein dynamics drive rapid ...
Hitomi Soumiya   +2 more
wiley   +1 more source

Effect of terahertz irradiation on DNA damage repair in living cells

open access: yesFEBS Open Bio, EarlyView.
We investigated the effect of terahertz (THz) wave irradiation on DNA double‐strand break (DSB) repair in living cells. We found that THz irradiation enhanced DSB repair at specific frequencies, whereas heat treatment inhibited it, indicating that this effect is nonthermal and frequency‐specific.
Yuya Ueno   +3 more
wiley   +1 more source

Исследование маркетинговой атрибуции и визуализации данных с помощью google analytics

open access: yesХабаршысы. Экономика сериясы, 2023
Формирование пользовательских путей к совершению конверсии, точек соприкосновения клиентов с брендом, воронка и их оценка являются актуальными вопросами в области маркетинга.
E. L. Khegay   +2 more
doaj  

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