Results 41 to 50 of about 5,083 (170)

Keratocystic odontogenic tumors related to Gorlin–Goltz syndrome: A clinicopathological study

Journal of Oral Biology and Craniofacial Research, 2016
Background: Assess clinicopathological features of patients with keratocystic odontogenic tumor (KCOT) associated with Gorlin–Goltz syndrome in our institution from 2004 to 2015.
Mohammed Israr Ul Khaliq, Ajaz A. Shah, Irshad Ahmad, Shahid Hasan, Sagar S. Jangam, Farah, Anwar   +6 more
doaj   +1 more source

Examining the Role of Artificial Intelligence in Assessment: A Comparative Study of ChatGPT and Educator‐Generated Multiple‐Choice Questions in a Dental Exam

European Journal of Dental Education, EarlyView.
ABSTRACT Aim To compare the item difficulty and discriminative index of multiple‐choice questions (MCQs) generated by ChatGPT with those created by dental educators, based on the performance of dental students in a real exam setting. Materials and Methods A total of 40 MCQs—20 generated by ChatGPT 4.0 and 20 by dental educators—were developed based on ...
Nezaket Ezgi Özer, Yusuf Balcı, Gaye Bölükbaşı, Betul İlhan, Pelin Güneri   +4 more
wiley   +1 more source

Gorlin Syndrome and Cowden Syndrome

The Keio Journal of Medicine
Gorlin syndrome and Cowden syndrome are hereditary diseases that are characterized by multiple malignancies, cutaneous symptoms, and various other abnormalities. Both disorders are caused by a mutation of the gene that regulates cell proliferation and growth, resulting in tumorigenesis. Representative mutations are mutation in the patched 1 gene (PTCH1)
Goto, Hiroyuki, Tateishi, Chiharu, Tsuruta, Daisuke   +2 more
openaire   +2 more sources

Integrated Molecular Profiling Improves Subtype Classification and Reveals Inherited Susceptibility in Medulloblastoma: Insights From a Real‐World Cohort

Cancer Medicine, Volume 15, Issue 5, May 2026.
ABSTRACT Background Medulloblastoma (MB) is a heterogeneous pediatric brain tumor characterized by distinct molecular subtypes. Although genomics and transcriptomics have improved subtype classification and informed targeted therapies, the clinical utility of integrated molecular profiling in real‐world settings remains incompletely defined. Methods We
Jiwei Song, Tiantian Han, Siqi Chen, Dongsheng Chen, Ziying Liu   +4 more
wiley   +1 more source

Nevoid basal cell carcinoma syndrome

Indian Journal of Dental Research, 2006
Binkley and Johnson first reported this syndrome in 1951. But it was in 1960, Gorlin-Goltz established the association of basal cell epithelioma, jaw cyst and bifid ribs, a combination which is now frequently known as Gorlin-Goltz syndrome as well as ...
Kannan Karthiga, Sundharam Sivapatha, Manikandan R   +2 more
doaj  

Gorlin-Goltz Syndrome with Multiple OKC in a 10-Year-Old Child: A Case Report

Journal of Multidisciplinary Dental Research
Gorlin-Goltz syndrome is rare multi-system disease, which is, characterized by neoplasms and other developmental abnormalities. 1 It is a hereditary condition inherited as an autosomal dominant trait and caused by abnormalities in the PTCH1 ...
Devadhakshayani Venkatesan, Nandhini B Selvarajan, Yash Suraj Latkar, D Vinola   +3 more
doaj   +1 more source

Pigmented Basal Cell Carcinoma Mimicking Melanoma in the Anal Area: A Case Report

Clinical Case Reports, Volume 14, Issue 5, May 2026.
ABSTRACT Early evaluation of persistent perianal lesions is essential even when symptoms appear mild or patients feel embarrassed to seek care. Pigmented basal cell carcinoma in this region is rare and may mimic melanoma clinically. Ongoing histopathological and immunohistochemical assessment is crucial to ensure correct diagnosis and timely surgical ...
Farnaz Araghi, Sareh Salarinejad, Azadeh Rakhshan, Hamideh Moravvej Farshi   +3 more
wiley   +1 more source

Gorlin Syndrome

South African Journal of Child Health, 2011
Naevoid basal cell carcinoma syndrome (NBCCS), also known as Gorlin syndrome, is an autosomal dominant syndrome of developmental anomalies associated with an increased risk of malignancies. Patients have multiple lesions, which may be subtle, and the diagnosis can easily be missed, leading to sub-optimal follow-up.
Geel, JA, Bennett, KG, Rigby, JM, Poole, JE   +3 more
  +5 more sources

Knuckle, Knuckle, Dimple, Dimple: Do Not Miss A Diagnostic Opportunity

Clinical Case Reports, Volume 14, Issue 4, April 2026.
Archibald's metacarpal sign is characterized by dimpling over the knuckles when the fist is clenched, resulting from relative shortening of the fourth and fifth metacarpals compared with the third. ABSTRACT Turner syndrome (TS) often presents with subtle or overlooked clinical signs, contributing to frequent diagnostic delays. We describe the case of a
Maria Chiara Pellegrin, Gianluca Tamaro, Alice Fachin, Egidio Barbi, Gianluca Tornese   +4 more
wiley   +1 more source

Coexistence of Medullary Thyroid Carcinoma and Bilateral Pheochromocytoma in MEN2A Syndrome: Atypical Presentation and Clinical Insights From a Case Report

Clinical Case Reports, Volume 14, Issue 4, April 2026.
ABSTRACT MEN2A may present with bilateral pheochromocytoma a decade before medullary thyroid carcinoma. This case highlights that high‐risk RET mutations must dictate surgical management regardless of benign cytology. Furthermore, it underscores the necessity of lifelong surveillance for late adrenal recurrences presenting as hypertensive crises.
Juan Carlos Vallejo‐Soto, Rogers Leonardo Baquero García, Álvaro Eduardo Granados Calixto, Juan Esteban Ortiz Elejalde, Silvana Barrera Rodríguez, Isabella González Guillén   +5 more
wiley   +1 more source