Results 51 to 60 of about 5,083 (170)

Incidence and Outcome of Infants With Cancer in Canada: A Report From Cancer in Young People in Canada Database

Pediatric Blood &Cancer, Volume 73, Issue 2, February 2026.
ABSTRACT Purpose Infants with cancer are rare and face unique challenges. Our study aims to describe the incidence of infantile cancers in Canada and to compare treatment‐related mortality (TRM) and their outcomes with those of older children. Methods We conducted a retrospective cohort study using the Cancer in Young People in Canada database ...
Samuel Sassine, Hallie Coltin, Maria Kondyli, Monia Marzouki, Nicolas Prud'homme, Nida Usmani, Sylvia Cheng, Lesleigh Abbott, Tony Truong, Sapna Oberoi, Ketan Kulkarni, Josée Brossard, Lynette Bowes, Paul Gibson, Donna L. Johnston, Sarah McKillop, Roona Sinha, Lillian Sung, Catherine Vezina, Laura Wheaton, Alexandra P. Zorzi, Marie‐Claude Pelland‐Marcotte, Thai Hoa Tran   +22 more
wiley   +1 more source

Syndrome in question: Gorlin-Goltz syndrome [PDF]

Anais Brasileiros de Dermatologia, 2016
The Nevoid Basal Cell Carcinoma Syndrome (NBCCS) is an uncommon disorder caused by a mutation in Patched, tumor suppressor gene. It is mainly characterized by numerous early onset basal cell carcinomas, odontogenic cysts of jaw and skeletal abnormalities. Due to the wide clinical spectrum, treatment and management of its modalities are not standardized
Pauline Lyrio Ribeiro, João Basílio de Souza Filho, Karina Demoner de Abreu, Marisa Simon Brezinscki, Christine Chambo Pignaton   +4 more
openaire   +3 more sources

The Metacarpophalangeal Pattern Profile: An Old Method With New Insights Into the Evaluation of Short Stature

American Journal of Human Biology, Volume 38, Issue 2, February 2026.
ABSTRACT Objective To characterize the metacarpophalangeal pattern profile (MCPP) of healthy children and adolescents from São Paulo, Brazil, and to establish percentile curves by chronological age (CA), bone age (BA), and sex using the LMS method. Additionally, to compare these findings with previous population‐based data and to apply the derived ...
Marcelo Damaso Maruichi, Bruno Telma Destailleur, Giulia Maesta Apelbaum, Carlos Alberto Longui, Cristiane Kochi   +4 more
wiley   +1 more source

A rare case report of Gorlin-Goltz’s syndrome: a multisystemic disorder of otolaryngological domain

The Egyptian Journal of Otolaryngology, 2023
Background Gorlin-Goltz’s syndrome (GGS) is an extremely rare autosomal dominant disorder showing a high penetrance and variable expressivity. Gorlin-Goltz’s syndrome is an infrequent multisystemic disease, which is usually characterized by numerous ...
Richa Richa, Vivek Kumar, Ayushree Ayushree   +2 more
doaj   +1 more source

A rare case of Gorlin–Goltz syndrome

The Egyptian Journal of Radiology and Nuclear Medicine
Background The Gorlin–Goltz syndrome (the Nevoid basal cell carcinoma syndrome (NBCCS)) is reviewed as a rare autosomal dominant syndrome caused by gene mutations located on chromosome arm 9 q.
Sara R. Hassan, Ayda A. Youssef, Esraa S. ElMallah   +2 more
doaj   +1 more source

Plaque‐type trichoblastoma and its siblings: A (follicular tumour) family history

JDDG: Journal der Deutschen Dermatologischen Gesellschaft, EarlyView.
Ines Bertlich, Ferdinand Toberer, Tilman Schulz, Dmitry V. Kazakov, Wolfgang Hartschuh   +4 more
wiley   +1 more source

Alcian blue‐positive stromal phenotype in basal cell carcinoma is associated with progression on first‐line hedgehog inhibitors

The Journal of Pathology: Clinical Research, Volume 12, Issue 1, January 2026.
Abstract Basal cell carcinoma (BCC) is the most frequent malignancy in fair‐skinned populations. Although curable in most cases, approximately 4% of patients develop locally advanced or metastatic disease (advBCC) requiring systemic therapy. Hedgehog pathway inhibitors (HHIs; vismodegib/sonidegib) constitute standard first‐line treatment, yet ...
Viola K DeTemple, Rudolf Stadler, Sabine Bredemeier, Sungyoung Chung, Katrin Schaper‐Gerhardt, Mareike Alter, Yenny Angela, Henner Stege, Ulrike Leiter, Jan Ohletz, Elisabeth Livingstone, Imke von Wasielewski, Jessica C Hassel, Julia Huynh, Christoffer Gebhardt, Claudia Pföhler, Ralf Gutzmer, Christina H Scheel   +17 more
wiley   +1 more source

License to Replicate: Mechanisms of Licensing Eukaryotic Origins for DNA Replication

BioEssays, Volume 48, Issue 1, January 2026.
Origin licensing constitutes the first step in initiating eukaryotic genome replication. Licensed origins are marked by an MCM double hexamer complex. This article reviews the molecular mechanisms of MCM double hexamer loading in yeast and higher eukaryotes, based on insights gained from biochemical reconstitution and structural analyses.
Victoria Frisbie, Franziska Bleichert
wiley   +1 more source

Incidental Tentorial Cerebelli Hypoplasia: A Case Report and Comprehensive Literature Review of Its Clinical and Imaging Characteristics

Case Reports in Medicine, Volume 2026, Issue 1, 2026.
Background Tentorial hypoplasia is a rare congenital condition characterized by underdevelopment or absence of the tentorium cerebelli, a dural structure separating the cerebrum from the cerebellum. It is often detected incidentally on computed tomography (CT) or magnetic resonance imaging (MRI) and may be associated with conditions such as Dandy ...
Husam Hamshary, Mosub Qatu, Fathi Milhem, Radi Kukhun, Zaid Sawaftah, Mohammad Bdair, Abdelfattah M. Dahmas, Qutaiba Ja’far A. Mahmoud, Omar Naseef, Mohammed Ibrahim Abu Kamesh, Poulami Jha   +10 more
wiley   +1 more source

Multiple jaw cysts-unveiling the Gorlin-Goltz syndrome

Contemporary Clinical Dentistry, 2015
Gorlin-Goltz syndrome or basal cell nevus syndrome is a comparatively rare syndrome characterized by basal cell nevi, odontogenic keratocysts, and skeletal anomalies. Diagnosis is based on the major and minor clinical and radiographic criteria.
S Manjima, Zameera Naik, Vaishali Keluskar, Anjana Bagewadi   +3 more
doaj   +1 more source