Results 131 to 140 of about 27,494 (252)

Age‐Dependent Differences in Canakinumab Safety: A Comprehensive Pharmacovigilance Analysis Using the FAERS Database

Pharmacology Research &Perspectives, Volume 14, Issue 3, June 2026.
ABSTRACT While the efficacy of canakinumab, an anti‐interleukin‐1β monoclonal antibody, is well‐established, its safety profile, particularly across different age groups, remains inadequately explored. Using the FDA Adverse Event Reporting System (FAERS) database, this study evaluated postmarketing safety by analyzing adverse event (AE) reports from ...
Youyang Wang, Ngasin Lam, Xiaoming Huang, Yang Jiao   +3 more
wiley   +1 more source

ARTHRITIS : THE PUBLIC HEALTH CHALLENGE FOR STATES [PDF]

The challenge facing our states and communities is how best to address the burden of arthritis and improve the health of entire population groups. By using a population-based approach, building partnerships to implement effective interventions, and ...

core  

HUBUNGAN POLA MAKAN DENGAN PENCEGAHAN GOUT ARTHRITIS DI KELURAHAN AERTEMBAGA DUA KECAMATAN AERTEMBAGA KOTA BITUNG

, 2022
Latar Belakang : Gout arthritis atau asam urat merupakan suatu penyakit yang menyerang sendi yang mengakibatkan nyeri yang amat sakit dan dapat mengakibatkan pembengkakan sampai tidak dapat berjalan.
MALARU, ANJELIA, Budiawan, Helly, Rumampuk, M. Vonny H.   +2 more
core  

Serum Uric acid level during the acute attacks of Gouty arthritis

Majallah-i Dānishgāh-i ̒Ulūm-i Pizishkī-i Bābul, 2003
Background and Objective: Gout is a condition characterized by acute arthritis and hyperuricemia, but the prevalence of hyperuricemia and the level of serum uric acid (SUA) in acute gout is not known exactly.
B Heidari, KH Bijani, SH Savad Koohi, E Shafigh   +3 more
doaj  

A Purified Biflavonoid Extract From Selaginella moellendorffii Alleviates Gout Arthritis via NLRP3/ASC/Caspase-1 Axis Suppression. [PDF]

Front Pharmacol, 2021
Zhang X, Liu Y, Deng G, Huang B, Kai G, Chen K, Li J.   +6 more
europepmc   +1 more source

Benzofuran‐Based Uricosuric Agents: History, Roles, and Challenges

ChemistrySelect, Volume 11, Issue 24, 25 June 2026.
Benzofuran‐based uricosuric agents represent a privileged medicinal chemistry scaffold for gout therapy. Structural optimization of benzbromarone‐related derivatives has improved hURAT1 inhibitory potency, metabolic stability, and urate‐lowering efficacy, while reducing hepatotoxic liability.
Raed M. Al‐Zoubi, Basma Hanbali, Mai Elaarag, Zainab Fares, Enas A. Al‐Hurani, Sally R. Al‐Zoubi, Mohanad Shkoor, Abdelali Agouni   +7 more
wiley   +1 more source

Metabolic dysfunction-associated fatty liver disease and the risk of gout: a UK Biobank prospective cohort study

European Journal of Medical Research
Background Gout, an inflammatory arthritis characterized by monosodium urate crystal deposition, affects 1–4% of the global population and demonstrates strong associations with metabolic syndrome.
Xin Liu, Yi Wang, Hui Song, Zi-bin Tian, Yan-gang Wang, Qian Yu, Chang Li, Qinghui Niu, Xiang-jia Zhu, Ying Chen   +9 more
doaj   +1 more source

Uric Acid, Colchicine and Chronic Inflammatory Diseases: A Cardiovascular Perspective

Metabolites
Based on the notion that inflammation plays a pivotal role in the development and progression of cardiovascular diseases (CV) and that hyperuricaemia is an independent CV risk factor, chronic inflammatory diseases such as gout and rheumatoid arthritis ...
Alessia Alunno, Francesco Carubbi, Claudio Ferri   +2 more
doaj   +1 more source

Coexistent rheumatoid arthritis and gout [PDF]

Arthritis & Rheumatism, 1985
openaire   +2 more sources

Functions of 1,25-dihydroxy vitamin D3, vitamin D3 receptor and interleukin-22 involved in pathogenesis of gout arthritis through altering metabolic pattern and inflammatory responses. [PDF]

PeerJ, 2021
Chen Y, Ma H, Du Y, Dong J, Jin C, Tan L, Wei R.   +6 more
europepmc   +1 more source