Results 101 to 110 of about 2,297,282 (312)

Optimizing the health workforce for Universal Health Coverage: a framework for analysis and action

Human Resources for Health
Background The health workforce or human resources for health (HRH) is the bedrock of an efficient healthcare system, and the consequences of HRH shortage are evident in poor health service delivery.
Gafar B. Alawode, Abdul-Rahman A. Ajibola, Morohunranti S. Sanusi, Ayomide B. Adewoyin, Kafayat A. Alawode   +4 more
doaj   +1 more source

Organoids in pediatric cancer research

FEBS Letters, EarlyView.
Organoid technology has revolutionized cancer research, yet its application in pediatric oncology remains limited. Recent advances have enabled the development of pediatric tumor organoids, offering new insights into disease biology, treatment response, and interactions with the tumor microenvironment.
Carla Ríos Arceo, Jarno Drost
wiley   +1 more source

Key drivers of 'good' corporate governance and the appropriateness of UK policy responses : final report [PDF]

, 2007
The DTI’s Corporate Law and Governance strategy aims to promote and deliver an effective framework for corporate governance in the UK, giving confidence to investors, business, and other stakeholders to underpin the relationship between an organisation
Allcock, Deborah, Filatotchev, Igor, Gospel, Howard, Jackson, Gregory   +3 more
core  

Disentangling scale approaches in governance research: comparing monocentric, multilevel, and adaptive governance [PDF]

, 2010
The question of how to govern the multiscale problems in today’s network society is an important topic in the fields of public administration, political sciences, and environmental sciences.
Dewulf, A., Lieshout, M., van, Termeer, C.J.A.M.   +2 more
core   +2 more sources

Reciprocal control of viral infection and phosphoinositide dynamics

FEBS Letters, EarlyView.
Phosphoinositides, although scarce, regulate key cellular processes, including membrane dynamics and signaling. Viruses exploit these lipids to support their entry, replication, assembly, and egress. The central role of phosphoinositides in infection highlights phosphoinositide metabolism as a promising antiviral target.
Marie Déborah Bancilhon, Bruno Mesmin
wiley   +1 more source

Phosphatidylinositol 4‐kinase as a target of pathogens—friend or foe?

FEBS Letters, EarlyView.
This graphical summary illustrates the roles of phosphatidylinositol 4‐kinases (PI4Ks). PI4Ks regulate key cellular processes and can be hijacked by pathogens, such as viruses, bacteria and parasites, to support their intracellular replication. Their dual role as essential host enzymes and pathogen cofactors makes them promising drug targets.
Ana C. Mendes, Guilherme M. Azevedo, Amanda P. Barcellos, Diana Bahia   +3 more
wiley   +1 more source

Transformation Across Land-Sea Governance: Future Research Opportunities

Ocean and Society
Transformation is heralded as a solution to the diverse and interconnected crises threatening natural environments and the livelihoods of those who depend on them.
Tegan Evans, Gianluca Ferraro, Pierre Failler   +2 more
doaj   +1 more source

Protein pyrophosphorylation by inositol pyrophosphates — detection, function, and regulation

FEBS Letters, EarlyView.
Protein pyrophosphorylation is an unusual signaling mechanism that was discovered two decades ago. It can be driven by inositol pyrophosphate messengers and influences various cellular processes. Herein, we summarize the research progress and challenges of this field, covering pathways found to be regulated by this posttranslational modification as ...
Sarah Lampe, Tanmay Kumar Mohanty, Rashna Bhandari, Dorothea Fiedler   +3 more
wiley   +1 more source

Maatlat Government-Governance

, 2009
In diverse publicaties wordt aangegeven dat er de laatste decennia in de relatie tussen de centrale overheid en de overige publieke en private actoren een verschuiving is opgetreden van government naar governance. Bij government bepaalt één dominante actor, de rijksoverheid, het beleid, terwijl de inbreng van andere actoren nihil is.
Vreke, J., Gerritsen, A.L., Kranendonk, R.P., Pleijte, M., Kersten, P.H., van den Bosch, F.J.P.   +5 more
openaire   +1 more source

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source