Results 111 to 120 of about 834,173 (313)

Metropolitan-Governance-Roundtable-Sydney.pdf

open access: yes, 2011
A summary paper of the International Roundtable on Metropolitan Governance held in Sydney in December ...
Graham Sansom
core  

Septin 9 PB domains coordinate centrosome positioning and microtubule acetylation to control epithelial polarity

open access: yesFEBS Letters, EarlyView.
Septin 9 polybasic domains couple phosphoinositide‐rich membrane binding to centrosome positioning, Golgi organization, and microtubule acetylation to control epithelial polarity. Their loss disrupts this axis, causing centrosome mispositioning, Golgi fragmentation, reduced microtubule acetylation, and polarity inversion via upregulation of the ...
Ting ting Cai   +4 more
wiley   +1 more source

Towards a conceptual framework for the study of shifts in modes of environmental governance : experiences form the Netherlands

open access: yes, 2012
In the last decade, many authors have observed shifts from government to governance in the environmental policy domain. However, a clear conceptual framework to differentiate between modes of environmental governance is lacking and our understanding of ...
Dieperink, C.   +12 more
core   +1 more source

Rab14 regulates the transport of human papillomavirus to the trans‐Golgi network for infectious cell entry

open access: yesFEBS Letters, EarlyView.
This study reveals that the small GTPase Rab14 is necessary for human papillomavirus (HPV) infection and plays an essential role in the transport of virions to the trans‐Golgi network (TGN). HPV in the early endosome (EE), which harbors GTP‐bound Rab14, is transported to the TGN through the switch of Rab14 from its GTP‐bound to GDP‐bound form.
Yoshiyuki Ishii, Iwao Kukimoto
wiley   +1 more source

Leveraging Resources for Governance Transformation

open access: yesJournal of Awareness-Based Systems Change
Democracies once considered stable are now exhibiting signs of systemic strain long familiar to much of the world, and governance systems everywhere face the challenge of moving from disruption toward reorganization.
Rob Ricigliano, Sid Hargro
doaj   +1 more source

Conclusion: Policy Implications of ESG–Agency Research and Reflections on the Road Ahead: Agency in Earth System Governance

open access: yes, 2020
− The role of the state as an agent of earth system governance has become more complex, contingent, and interdependent. − Although participatory and collaborative processes have contributed to more effective, equitable, and legitimate environmental ...
Gerlak, Andrea K.   +9 more
core   +1 more source

Degradation mechanism of the von Willebrand factor A2 domain by nattokinase

open access: yesFEBS Letters, EarlyView.
Nattokinase, a natto‐derived protease, exhibits potent antithrombotic effects. This study demonstrates that nattokinase directly cleaves the von Willebrand factor (vWF) A2 domain in vitro. Unlike the native regulator ADAMTS13, nattokinase degrades folded vWF independently of shear stress.
Ryuichi Hyakumoto   +3 more
wiley   +1 more source

Introduction 'Governance for Drought Resilience'

open access: yes, 2016
This book is about governance for drought resilience. But that simple sentence alone might rouse several questions. Because what do we mean with drought, and how does that relate to water scarcity?
Bressers, Nanny   +3 more
core   +1 more source

Modulation of Homer1 EVH1 domain internal dynamics by putative autism‐associated mutations

open access: yesFEBS Letters, EarlyView.
The putative autism‐associated M65I and S97L variants of the EVH1 domain of the postsynaptic scaffold protein Homer1 do not exhibit substantial changes in their overall structure or partner binding. Both of them, but especially the M65I variant, show altered internal dynamics relative to the wild‐type domain on the μs‐ms timescale, indicated by the ...
Fanni Farkas   +6 more
wiley   +1 more source

Metropolitan-Governance-Roundtable-Brisbane.pdf

open access: yes, 2011
A summary paper of the Second International Roundtable on Metropolitan Governance held in Brisbane in August ...
Graham Sansom
core  

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