Results 111 to 120 of about 1,144,182 (342)

The newfound relationship between extrachromosomal DNAs and excised signal circles

FEBS Letters, EarlyView.
Extrachromosomal DNAs (ecDNAs) contribute to the progression of many human cancers. In addition, circular DNA by‐products of V(D)J recombination, excised signal circles (ESCs), have roles in cancer progression but have largely been overlooked. In this Review, we explore the roles of ecDNAs and ESCs in cancer development, and highlight why these ...
Dylan Casey, Zeqian Gao, Joan Boyes
wiley   +1 more source

Faith-Based and Community Organizations as Human Security Actors: Bridging Governance Gaps in Kwara North

Bulletin of "Carol I" National Defense University
This study investigates the role of faith-based and community organizations in advancing human security through poverty alleviation initiatives in Kwara North, Nigeria. Situated within the broader discourse on non-state actors and governance, it examines
Abdulrauf AMBALI, Alabi ABDULLAHI, Moshood Olayinka SALAHU SALAHU, Ibrahim A. ADEYANJU   +3 more
doaj   +1 more source

Putting inclusion into practice: how urban professionals give shape to participatory governance approaches in marginalized neighborhoods

, 2023
Simone van de Wetering, Martijn Groenleer   +1 more
openalex   +1 more source

Government governance [PDF]

International Journal of Disclosure and Governance, 2010
openaire   +1 more source

Cell wall target fragment discovery using a low‐cost, minimal fragment library

FEBS Letters, EarlyView.
LoCoFrag100 is a fragment library made up of 100 different compounds. Similarity between the fragments is minimized and 10 different fragments are mixed into a single cocktail, which is soaked to protein crystals. These crystals are analysed by X‐ray crystallography, revealing the binding modes of the bound fragment ligands.
Kaizhou Yan, Mathew Stanley, Olawale Raimi, Andrew T. Ferenbach, Helge C Dorfmueller, Daan M. F. van Aalten   +5 more
wiley   +1 more source

Cell density–dependent nuclear‐cytoplasmic shuttling of SETDB1 integrates with Hippo signaling to regulate YAP1‐mediated transcription

FEBS Letters, EarlyView.
At low cell density, SETDB1 and YAP1 accumulate in the nucleus. As cell density increases, the Hippo pathway is gradually activated, and SETDB1 is associated with increased YAP1 phosphorylation. At high cell density, phosphorylated YAP1 is sequestered in the cytoplasm, while SETDB1 becomes polyubiquitinated and degraded by the ubiquitin–proteasome ...
Jaemin Eom, Jaewoong Jang, Jung Sun Park, Yong‐Kook Kang   +3 more
wiley   +1 more source

Pharmaceutical payments to Japanese certified hematologists: a retrospective analysis of personal payments from pharmaceutical companies between 2016 and 2019

Blood Cancer Journal, 2022
Eiji Kusumi, Anju Murayama, Sae Kamamoto, Moe Kawashima, Makoto Yoshida, Hiroaki Saito, Toyoaki Sawano, Erika Yamashita, Tetsuya Tanimoto, Akihiko Ozaki   +9 more
doaj   +1 more source

Security Expenditures and Fiscal Strain: The Impact of the Farmer-Herder Conflict on Public Finance in Northern Nigeria (2015–2024)

Bulletin of "Carol I" National Defense University
Nigeria has been entrapped in a cycle of insecurity which has not only affected the lives and properties of its citizens, but as had a colossal effect on the macro-economy of the state.
Ibrahim O. SALAWU, Moshood Olayinka SALAHU, Emmanuel Oyewole LAMBE, Hassan Seyid ISHOLA   +3 more
doaj   +1 more source

A Survey of Corporate Governance

, 1996
Andrei Shleifer, Robert W. Vishny
semanticscholar   +1 more source

Inhibiting stearoyl‐CoA desaturase suppresses bone metastatic prostate cancer by modulating cellular stress, mTOR signaling, and DNA damage response

FEBS Letters, EarlyView.
Bone metastasis in prostate cancer (PCa) patients is a clinical hurdle due to the poor understanding of the supportive bone microenvironment. Here, we identify stearoyl‐CoA desaturase (SCD) as a tumor‐promoting enzyme and potential therapeutic target in bone metastatic PCa.
Alexis Wilson, Mackenzie K Herroon, Shane Mecca, Laimar C Garmo, Jacob Lindquist, Shrila Rajendran, Steve M. Patrick, Izabela Podgorski   +7 more
wiley   +1 more source