Results 221 to 230 of about 1,043,166 (320)

Pharmacological effects of osimertinib on a chicken chorioallantoic membrane xenograft model with the EGFR exon‐19‐deleted advanced NSCLC mutation

FEBS Open Bio, EarlyView.
Osimertinib reduces angiogenesis and PDL1 expression in in ovo tumors, transforming them into ‘cold tumors’ with lower immune activity. Anatomopathological and transcriptomic analyses highlight its therapeutic impact on tumor biology. This study underscores osimertinib's potential to reshape the tumor microenvironment and provides insights into its ...
David Barthélémy, Arnaud Vigneron, Xavier Rousset, Jérome Guitton, Emmanuel Grolleau, Margaux Raffin, Julie Balandier, Gaëlle Lescuyer, Mathilde Bardou, Florence Geiguer, Sébastien Couraud, Claire Bardel, Jean Viallet, Nazim Benzerdjeb, Léa Payen   +14 more
wiley   +1 more source

US institutional investors look at corporate governance in the 1990s

, 1993
Michael Useem, Edward H. Bowman, Jennifer Myatt, Craig W. Irvine   +3 more
openalex   +1 more source

Fiscal Federalism and Macroeconomic Governance: For Better or For Worse? [PDF]

, 1999
Anwar Shah
openalex   +1 more source

Identification of inhibitors of the Salmonella FraB deglycase, a drug target

FEBS Open Bio, EarlyView.
A high‐throughput screen was used to identify inhibitors of Salmonella FraB, a drug target. Characterization of top hits (identified after an additional counter screen) revealed that some triazolidines, thiadiazolidines, and triazolothiadiazoles are mixed‐type inhibitors of FraB.
Jamison D. Law, Yuan Gao, Sravya Kovvali, Pankajavalli Thirugnanasambantham, Vicki H. Wysocki, Brian M. M. Ahmer, Venkat Gopalan   +6 more
wiley   +1 more source

Good Governance and Trade Policy: Are They the Keys to Africa's Global Integration and Growth? [PDF]

, 1999
Francis Ng, Alexander J. Yeats
openalex   +1 more source

The urgency of centering safety-net organizations in AI governance. [PDF]

NPJ Digit Med
Nong P, Maurer E, Dwivedi R.
europepmc   +1 more source

Beyond digital twins: the role of foundation models in enhancing the interpretability of multiomics modalities in precision medicine

FEBS Open Bio, EarlyView.
This review highlights how foundation models enhance predictive healthcare by integrating advanced digital twin modeling with multiomics and biomedical data. This approach supports disease management, risk assessment, and personalized medicine, with the goal of optimizing health outcomes through adaptive, interpretable digital simulations, accessible ...
Sakhaa Alsaedi, Xin Gao, Takashi Gojobori   +2 more
wiley   +1 more source

English law in the age of the Black Death, 1348-1381: a transformation of governance and law

, 1994

openalex   +2 more sources

Governance in the University of California: the transformation of politics into administration [PDF]

, 1998
Martín Trow
openalex   +1 more source

Regulation and governance for the implementation and management of point-of-care testing in Australia: a scoping review. [PDF]

BMC Public Health
Prestedge J, Kaufman C, Williamson DA.
europepmc   +1 more source