Results 151 to 160 of about 18,243 (254)

Who's afraid of synthetic data? Hybrid approaches to deliver medical digital twins. [PDF]

Inform Med Unlocked
Vanin J, Hagar A, Glazier JA.
europepmc   +1 more source

CD47 promotes mitogen‐activated protein kinase and epithelial‐to‐mesenchymal transition molecular programs to drive prometastatic phenotypes in non‐small cell lung cancer

Molecular Oncology, EarlyView.
Beyond its role in immune evasion, this study identified that CD47 drives tumor‐intrinsic signaling in non‐small cell lung cancer (NSCLC). Transcriptomic profiling and functional studies revealed that CD47 regulates cell adhesion, migration, and metastasis through an ERK–EMT signaling axis.
Asa P.Y. Lau, Lilian G. Zhai, Ryunosuke Hoshi, Zackary Rousseau, Abraam Zakhary, Yin Fang Wu, Rola M. Saleeb, Heyu Ni, Kelsie L. Thu   +8 more
wiley   +1 more source

Taiwan's Smart Healthcare Value Chain: AI Innovation from R&D to Industry Deployment. [PDF]

Healthcare (Basel)
Lin TM, Yang HW, Han CC, Lin CS.
europepmc   +1 more source

Cell‐cycle‐specific lesion evolution rather than inhibition of double‐strand‐break repair underpins cisplatin radiosensitization

Molecular Oncology, EarlyView.
We analyze cisplatin–DNA adducts (CDAs) and double‐strand breaks (DSBs) in a cell‐cycle‐dependent manner. We find that CDAs form similarly across all cell cycle phases. DSBs arise only in S‐phase. CDAs might not directly impair DSB repair, but S‐phase DSB lesions evolve in the presence of CDAs and disrupt repair in G2, also causing radiosensitization ...
Ye Qiu, Xixi Lin, Emil Mladenov, Veronika Mladenova, Jürgen Thomale, Ali Sak, Yao Wang, Yunxuan Deng, Eleni Gkika, Martin Stuschke, George Iliakis   +10 more
wiley   +1 more source

HealthData@MAD-R&I: Protocol for Design and Development of a Regional Health Data Infrastructure to Enable Secondary Use of Health Data in Research and Innovation.

JMIR Res Protoc
León-García M, Álvarez-Pérez S, Gesto-Gómez J, Urbano-Molina C, Soto-Díaz S, Cárdenas-Valladolid J, Rodríguez-Rodríguez L, Díaz-Holgado A, Del Cura-González I, De La Cruz-Bertolo J, García-Barrio N, Cruz-Bermúdez JL, García-Fernández C, Rodríguez-Antolín C, García-Aldars L, Moreda-Sánchez EM, Roldán López Á, Veganzones Alonso-Cortés JM, Gonzalez Gonzalez AI, Salinero-Fort MA, HealthData@MAD-R&I Working Group.   +20 more
europepmc   +1 more source

Preparing for the Futures of Health Professions Education in the Philippines. [PDF]

Acta Med Philipp
Parial LLB.
europepmc   +1 more source

Hijacking emergency granulopoiesis: Neutrophil ontogeny and reprogramming in cancer

Molecular Oncology, EarlyView.
Neutrophils are highly plastic innate immune cells; their functions in cancer extend beyond the tumour microenvironment. This Review summarises current understanding of neutrophil maturation and heterogeneity and highlights tumour‐induced granulopoiesis as a systemic programme that expands immature, immunosuppressive neutrophils via tumour‐derived ...
Gabriela Marinescu, Yi Feng
wiley   +1 more source

Study on urban passenger transport carbon reduction pathways based on system dynamics. [PDF]

Sci Rep
Liu R, Liu N.
europepmc   +1 more source

Transcriptional profiling of circulating extracellular vesicles from prebiopsy prostate cancer patients

Molecular Oncology, EarlyView.
RNA profiling of circulating extracellular vesicles (EVs) from blood samples of men undergoing prostate biopsy identifies transcripts associated with clinically significant prostate cancer. Integrative analysis with public tumor datasets links EV‐derived gene signatures to tumor stage and progression‐free survival, highlighting CASP3, XRCC2, and RIT1 ...
Stefan Werner, Pierre Tennstedt, Randi C. Pose, Christian Müller, Katharina Besler, Svenja Schneegans, Malik Alawi, Marie C. Roesch, Sven Peine, Desiree Bonci, Joanna Budna‐Tukan, Evi Lianidou, Catherine Alix‐Panabières, Derya Tilki, Klaus Pantel   +14 more
wiley   +1 more source

Piloting an Interpretive External Quality Assurance Model for Genomic Testing for Childhood Syndromes and Intellectual Disability. [PDF]

J Mol Diagn
Lundie B, Chai SY, Byrne AB, Azmanov D, Christodoulou J, Haas MA, Kassahn KS, Lunke S, Stott A, Thompson BA, Badrick T, Bennetts B.   +11 more
europepmc   +1 more source