Results 161 to 170 of about 18,243 (254)

Longitudinal circulating tumor DNA profiling in patients with advanced endometrial cancer using an off‐the‐shelf targeted NGS panel

Molecular Oncology, EarlyView.
Intratumour heterogeneity complicates precision management of advanced endometrial cancer. Circulating tumor DNA (ctDNA) offers a minimally invasive strategy to capture tumor evolution and therapeutic resistance. Here, we compare tumor‐agnostic NGS with tumor‐informed ddPCR, outlining their relative sensitivity, concordance, and clinical implications ...
Carlos Casas‐Arozamena, Karin Teien Lande, Eva Diaz, Ana Vilar, Juan Cueva, Efigenia Arias, Victoria Sampayo, Alicia Abalo, Nerea González, Eva Colás, Antonio Gil‐Moreno, Miguel Abal, Gema Moreno‐Bueno, Therese Sørlie, Kristina Lindemann, Laura Muinelo‐Romay   +15 more
wiley   +1 more source

Global Initiative on AI for Health (GI-AI4H): strategic priorities advancing governance across the United Nations. [PDF]

NPJ Digit Med
Muralidharan V, Ng MY, AlSalamah S, Pujari S, Kalra K, Singh R, Schalet D, Olantuji T, Malpani R, Matin RN, Omiye JA, Zhao Y, Sands A, Reis A, Diaz Mendoza JE, Hernandez-Boussard T, Daneshjou R, Labrique AB.   +17 more
europepmc   +1 more source

Interaction of HS1BP3 with cortactin modulates TKS5 localisation, cell secretion and cancer malignancy

Molecular Oncology, EarlyView.
Here, we demonstrate that HS1BP3 interacts with Cortactin through a proline‐rich region (PRR3.1) and show that this interaction, and HS1BP3 itself, promote cancer cell proliferation and invasion. Inhibition of this interaction leads to build‐up of TKS5 in multivesicular endosomes and altered secretion of CD63 and CD9, providing an explanation for the ...
Arja Arnesen Løchen, Kristiane Søreng, Chiara Veroni, Laura Trachsel‐Moncho, Nagham Asp, Robin Gaupset, Lars Gustav Lyckander, Helene Knævelsrud, Lars Eftang, Anne Simonsen   +9 more
wiley   +1 more source

Household Income Diversification and Food Insecurity: A Case Study of Afghanistan. [PDF]

Foods
Niazi R, Liu A, Han J, Hassan S, Elham H, Osewe M.   +5 more
europepmc   +1 more source

Proteasome inhibitor, ixazomib prevents topoisomerase‐I degradation and reverses irinotecan resistance in colorectal cancer

Molecular Oncology, EarlyView.
Ixazomib inhibits proteasome‐mediated degradation of topoisomerase I induced by irinotecan, thereby restoring drug sensitivity and promoting tumor cell death in colorectal cancer. Irinotecan, a topoisomerase I (topoI) inhibitor, is widely used for colorectal cancer, but resistance remains a major clinical challenge.
Yuho Ebata, Koji Ando, Hirofumi Hasuda, Koshi Mimori, Elizabeth C. Unan, Siddhartha Pulukuri, Aahana Tiku, Allison Berger, Eiji Oki, Ajit Bharti, Tomoharu Yoshizumi   +10 more
wiley   +1 more source

Centers for Medicare & Medicaid Services Approval of Cardiac Ablations in Ambulatory Surgery Centers: Challenges and Emerging Models Shaping the Future of Cardiac Electrophysiology. [PDF]

J Innov Card Rhythm Manag
Aryana A, Swarup V.
europepmc   +1 more source

Synthesis of the Commission’s management achievements in 2006. COM (2007) 274 final, 20 May 2007 [PDF]

, 2007

core  

Molecular cancer prevention: Intercepting disease

Molecular Oncology, EarlyView.
Oncological practice must evolve, from treating established tumours to proactive cancer interception before clinical manifestation. This will require mechanistic insight into tumour initiation, validated biomarkers of early disease development and redesigned clinical trials, enabling cancer interception to become a core pillar of oncology with the ...
Charlotte Grieco, Tej Pandya, Charles Swanton   +2 more
wiley   +1 more source

Data science and artificial intelligence for maternal, newborn and child health: scoping review and thematic analysis. [PDF]

BMC Public Health
Akuze J, Otieno GP, Amare SY, Ngatia B, Wanduru P, Kirakoya-Samadoulougou F, Kananura RM, Amouzou A, Estifanos AS, Ohuma EO.   +9 more
europepmc   +1 more source

ITMA - IT Integration in mergers and acquisitions [PDF]

, 2017
Burke, Declan, Kovela, Serhiy
core   +1 more source