Results 141 to 150 of about 8,009,603 (305)
FEBS Letters, EarlyView.How do genomes gain new functional parts? In eukaryotes, which tend to evolve under weak selection, much of the genome is junk. Palazzo and Qiu borrow the logic of Markov chains to show how non‐functional DNA becomes functional through the appearance of intermediate states, which arise due to epistasis, buffering, and biochemical messiness, allowing ...
Alexander F. Palazzo, Yi Qiu
wiley +1 more source
Cogent Economics & FinanceIn an era of geopolitical volatility and environmental strain, achieving the dual objectives of climate action and sustainable growth requires robust institutions capable of transforming risk into resilience.
Ridwan Lanre Ibrahim +5 more
doaj +1 more source
Governance of a complex system: water [PDF]
, 2014 This paper sets out a complex adaptive systems view of water governance. Overview Fresh water is a life - enabling resource as well as the source of spiritual, social and economic wellbeing and development.
Elizabeth Eppel
core
Prospecting the protein design landscape
FEBS Letters, EarlyView.This review outlines the current state of various protein design approaches. We discuss the current possibilities enabled by recently released tools, highlight future avenues to pursue in protein design, and underscore the crucial role of key databases and resources for successful protein design workflows.
Jakob R. Riccabona +4 more
wiley +1 more source
Income inequality and economic complexity in Africa: the moderating role of governance quality
Cogent Social SciencesThis study examines the relationship between economic complexity and income inequality in 24 selected African countries. Specifically, it investigates the moderating role of governance quality in the link between income inequality and economic complexity.
Amsalu Bedemo Beyene
doaj +1 more source
International review of data quality
, 2011 This international review is the first step in the process of developing standards for data quality which is part of the information governance standards development ...
Health Information and Quality Authority (HIQA)
core
Artificial molecular machines and motors—Design and control of nanoscale motion
FEBS Letters, EarlyView.Molecules are constantly moving because of thermal fluctuations, but random motion alone cannot be exploited to perform directional tasks. Artificial molecular machines use chemical, electrical, or light energy to bias this motion. Molecular shuttles, rotary motors, and supramolecular pumps illustrate how nanoscale movement can be controlled and ...
Leonardo Andreoni, Alberto Credi
wiley +1 more source
Mental health within ESG frameworks: a narrative and descriptive cross-national analysis
Frontiers in Public HealthDespite the growing use of environmental, social, and governance criteria for evaluating sustainability and institutional performance, mental health remains at the periphery of mainstream discourse on the topic.
Emanuela Resta +4 more
doaj +1 more source
A context‐dependent modulatory role for eIF6 in acquired resistance to vemurafenib in melanoma
FEBS Letters, EarlyView.Acquired resistance to vemurafenib upregulates the translation factor eIF6 in melanoma cells. Silencing eIF6 in resistant cells reduces proliferation and partially restores drug sensitivity, whereas its overexpression increases sensitivity across melanoma lines regardless of BRAF status, via modulation of mTOR, S6K, and MAPK signaling.
George Kyriakopoulos +9 more
wiley +1 more source
Governance matters VIII : aggregate and individual governance indicators 1996-2008 [PDF]
This paper reports on the 2009 update of the Worldwide Governance Indicators (WGI) research project, covering 212 countries and territories and measuring six dimensions of governance between 1996 and 2008: Voice and Accountability, Political Stability ...
Kraay, Aart +2 more
core